Results 91 to 100 of about 2,335,760 (337)

Cellulose acetate phthalate, a common pharmaceutical excipient, inactivates HIV-1 and blocks the coreceptor binding site on the virus envelope glycoprotein gp120 [PDF]

, 2001
BACKGROUND: Cellulose acetate phthalate (CAP), a pharmaceutical excipient used for enteric film coating of capsules and tablets, was shown to inhibit infection by the human immunodeficiency virus type 1 (HIV-1) and several herpesviruses. CAP formulations
A Boyum, A Robert Neurath, A Trkola, A Trkola, AR Neurath, AR Neurath, AR Neurath, AR Neurath, AR Neurath, AR Neurath, AR Neurath, Asim K Debnath, CD Rizzuto, CK Lapham, CM Javan, DR Burton, DR Littman, EA Berger, F Cocchi, G Alkhatib, H Choe, H Deng, J Bilello, JA Este, JC Lee, K Javaherian, KH Manson, L Wu, L Xiao, M Baba, M Baba, M Moulard, M Thali, MA Skinner, MC Peitsch, Nathan Strick, P Greenhead, PD Kwong, RA Anderson, RA Maguire, RF Speck, RJ Shattock, S Harada, S Laal, S Matsushita, S Rusconi, S Shaunak, T Dragic, T Gyotoku, T Kawamura, T Muster, TN Hart, WR Melander, Y Feng, YI Rumyantseva, Yun-Yao Li   +55 more
core   +3 more sources

Leveraging Design of Experiments to Unravel the Amplification Mechanism of Single‐Molecule Wide‐Field Biosensors

Advanced Materials Interfaces, EarlyView.
Detecting single molecules on large interfaces is challenging due to minimal perturbations on the sensing surface. Some biological systems achieve this feat using amplification mechanisms, but their molecular foundations remain unclear. To investigate, a Design of Experiments (DoE) approach examines how pH and ionic strength in conditioning solutions ...
Michele Catacchio, Mariapia Caputo, Lucia Sarcina, Cinzia Di Franco, Matteo Piscitelli, Erika Castrignanò, Paolo Bollella, Gaetano Scamarcio, Eleonora Macchia, Luisa Torsi   +9 more
wiley   +1 more source

Characterization of the longitudinal HIV-1 quasispecies evolution in HIV-1 infected individuals co-infected with Mycobacterium tuberculosis [PDF]

, 2010
One of the earliest and most striking observations made about HIV is the extensive genetic variation that the virus has within individual hosts, particularly in the hypervariable regions of the env gene which is divided into 5 variable regions (V1-V5 ...
Leulebirhan, Tsigereda Biru
core  

Implantable Microarray Patch: Engineering at the Nano and Macro Scale for Sustained Therapeutic Release via Synthetic Biodegradable Polymers

Advanced Materials Technologies, Volume 10, Issue 6, March 18, 2025.
This review focuses on the application of synthetic biodegradable microarray patches (MAPs) in sustained drug delivery. Compared to conventional MAPs which release drugs into the skin in an immediate manner, these implantable MAPs release drugs into skin microcirculation gradually as the biodegradable polymers degrade, thus offering sustained release ...
Li Zhao, Akmal Hidayat Bin Sabri, Mary B. McGuckin, Linlin Li, Zihao Wang, Eneko Larrañeta, Ryan F. Donnelly   +6 more
wiley   +1 more source

Trafficking and Human Rights in Nepal: Community Perceptions and Policy and Program Responses [PDF]

, 2001
This report from the Population Council's Horizons program summarizes the policy analysis, documentation of current intervention models, and community-based study of trafficking in the context of an emerging HIV/AIDS epidemic in ...
Catrin Evans, Celine Costello Daly, Dill R. Dahal, Jyoti Sanghera, Nick Langton, Pankaja Bhattarai, Ratna Kapur, Siobhan Crowley, Vaishali Sharma Mahendra   +8 more
core   +1 more source

Direct Access to α,β‐Unsaturated γ‐Lactams via Palladium‐Catalysed Carbonylation of Propargylic Ureas.

Advanced Synthesis &Catalysis, Volume 367, Issue 5, March 4, 2025.
Abstract Additive carbonylations typically necessitate strong nucleophiles, such as alcohols or amines. In this study, we carbonylated a poorly nucleophilic urea, under oxidant‐free conditions. Our straightforward carbonylative strategy enables access to versatile α,β‐unsaturated γ‐lactams featuring an aminocarbonyl fragment, utilizing readily ...
Debora Schiroli, Aleksandr Voronov, Francesco Pancrazzi, Nunzio Iraci, Salvatore Vincenzo Giofrè, Beatrice Macchi, Valeria Stefanizzi, Raffaella Mancuso, Bartolo Gabriele, Paolo Pio Mazzeo, Luca Capaldo, Nicola Della Ca'   +11 more
wiley   +1 more source

Sex differences in HIV effects on visual memory among substance-dependent individuals [PDF]

, 2016
HIV’s effects on episodic memory have not been compared systematically between male and female substance-dependent individuals. We administered the Brief Visuospatial Memory Test–Revised (BVMT–R) to 280 substance-dependent HIV+ and HIV– men and women ...
Gonzalez, Raul, Keutmann, Michael K., Maki, Pauline M., Martin, Eileen M., Rubin, Leah H., Vassileva, Jasmin   +5 more
core   +2 more sources

Digital Bioassays on the Slipchip Microfluidic Devices

Advanced Sensor Research, EarlyView.
This review summarizes recent advances in SlipChip‐based digital bioassays, highlighting their simple “load and slip” operation for fluid partitioning which eliminate the need for sophisticated fluidic systems. Applications include digital nucleic acid analysis, digital protein analysis and single‐cell analysis, demonstrating the platform‘s potential ...
Qingqing Luo, Ziqing Yu, Weiyuan Lyu, Yang Luo, Lei Xu, Feng Shen   +5 more
wiley   +1 more source

Identifying HIV infection in South African women: How does a fourth generation HIV rapid test perform?

African Journal of Laboratory Medicine, 2011
Background: HIV rapid tests (RT) play an important role in tackling the HIV pandemic in South Africa. Third generation RT that detect HIV antibodies are currently used to diagnose HIV infection at the point of care.
Kapila Bhowan, Emma Kalk, Sonjiha Khan, Gayle Sherman   +3 more
doaj   +1 more source

Concealment, communication and stigma: The perspectives of HIV-positive immigrant Black African men and their partners living in the United Kingdom [PDF]

, 2015
This study explored the perspectives of Black men, originally from East Africa, living in the United Kingdom and their families on what it means to live with diagnosed HIV.
Abigail Locke, Andrew Clifton, Bob Heyman, Glaser BG, John OA Owuor, Public Health England, Strauss AL, Van Wyk B   +7 more
core   +1 more source