Results 91 to 100 of about 2,248,861 (362)

Nuclear Translocation of S100A9 Triggers Senescence of Human Amnion Fibroblasts by De‐Repressing LINE1 Via Heterochromatin Erosion at Parturition

Advanced Science, EarlyView.
This study shows that the classical secretory protein S100 calcium‐binding protein A9 (S100A9) can translocate to the nucleus upon de‐phosphorylation at Thr 113 in human amnion fibroblasts at parturition, where S100A9 induces heterochromatin erosion through segregation of the heterochromatin maintenance protein, resulting inLong Interspersed Nuclear ...
Fan Zhang, Meng‐Die Li, Fan Pan, Wen‐Jia Lei, Yang Xi, Li‐Jun Ling, Leslie Myatt, Kang Sun, Wang‐Sheng Wang   +8 more
wiley   +1 more source

Chemsex, sexualized drug use and emotional vulnerability among men who have sex with men (MSM): a one-month survey in a STI/HIV center

BMC Public Health
Background Chemsex, characterized by the intentional use of specific drugs to enhance sexual experiences during group sessions, represents a challenge for the health of some sexually active communities, such as men who have sex with men (MSM).
Stella Capodieci, Mauro Zaccarelli, Christof Stingone, Eugenia Giuliani, Valentina Cafaro, Laura Gianserra, Maria Gabriella Donà, Alessandra Latini, Massimo Giuliani   +8 more
doaj   +1 more source

Diagnostic performance of APRI and FIB-4 for confirming cirrhosis in Indonesian HIV/HCV co-infected patients

BMC Infectious Diseases, 2020
Background After successful of antiretroviral therapy, highly effective direct acting antiviral (DAA) make HCV elimination reasonable in HIV/HCV co-infected patients.
Evy Yunihastuti, Bramantya Wicaksana, Andrian Wiraguna, Ainum Jhariah Hidayah, Fhadilla Amelia, Veritea Natali, Alvina Widhani, Andri Sanityoso Sulaiman, Juferdy Kurniawan   +8 more
doaj   +1 more source

HIV, TB and ART: the CD4 enigma [PDF]

arXiv, 2012
The concentration of CD4 T-lymphocytes (CD4 count), in a person's plasma is widely used to decide when to start HIV-positive people on anti-retroviral therapy (ART) and to predict the impact of ART on the future course of HIV and tuberculosis (TB). However, CD4 cell-counts vary widely within and among populations and depend on many factors besides HIV ...
arxiv  

A Joint Spatial Conditional Auto-Regressive Model for Estimating HIV Prevalence Rates Among Key Populations [PDF]

arXiv, 2020
Ending the HIV/AIDS pandemic is among the Sustainable Development Goals for the next decade. In order to overcome the gap between the need for care and the available resources, better understanding of HIV epidemics is needed to guide policy decisions, especially for key populations that are at higher risk for HIV infection.
arxiv  

Getting to Zero HIV Cases in San Francisco: Reconceptualizing Housing as Public Health Infrastructure in the Framework of HIV Prevention and Treatment [PDF]

, 2019
The City and County of San Francisco, originally ground zero for the HIV epidemic in the United States, is redefining public health HIV interventions, potentially positioning San Francisco as one of the first major metropolitan cities in the world to ...
Zaragoza, Gaspar
core  

A Versatile High‐Throughput Single‐Cell Screening Platform for Profiling Antigen‐Specific Long‐Lived B Cells in Blood and Bone Marrow

Advanced Science, EarlyView.
The MoSMAR‐chip platform provides a high‐throughput and cost‐effective tool for identifying and characterizing antigen‐specific antibody‐secreting cells (ASCs) and memory B cells (MBCs) at the single‐cell level. The ASCs from coronavirus disease 2019 (COVID‐19) vaccine‐immunized mice were successfully analyzed, revealing diverse neutralizing antibodies
Tian Zhao, Yuqing Lei, Chang Liu, Dong Zhang, Kaiyi Li, Sisi Shan, Chenyu Li, Zimeng Wei, Yuhan Yang, Ting Zhang, Kai Sun, Haoran Sun, Linqi Zhang, Peng Liu   +13 more
wiley   +1 more source

Low-level genital HIV shedding in Thai HIV-infected women with suppressed plasma viral load after menopause: a longitudinal study

Journal of Virus Eradication, 2017
Objectives: First, to evaluate the longitudinal changes of HIV RNA in genital secretions in HIV-positive women with plasma HIV RNA 50 copies/mL in 27% of the participants, and in 40% after menopause. The GVL was
Nadia Kancheva Landolt, Tanya Do, Naruporn Kasipong, Rosalin Kriengsinyot, Sasiwimol Ubolyam, Apicha Mahanontharit, Tippawan Pankam, Tanakorn Apornpong, Anchalee Avihingsanon, Jintanat Ananworanich, Nittaya Phanuphak, Surasith Chaithongwongwatthana   +11 more
doaj  

Complications of high volume circumcision: glans amputation in adolescents; a case report

BMC Urology, 2019
Background The past four years has seen a rapid roll-out of male medical circumcision services in South Africa in response to clinical trials showing circumcision prevents HIV acquisition in heterosexual men.
Mmatsie Manentsa, Hilary Mukudu, Nthabiseng Koloane, Ashley Ringane, Eleanor Matta, Neil A. Martinson, Limakatso Lebina   +6 more
doaj   +1 more source

Antiretroviral therapy to prevent HIV acquisition in serodiscordant couples in a hyperendemic community in rural South Africa [PDF]

, 2016
Background. Antiretroviral therapy (ART) was highly efficacious in preventing human immunodeficiency virus (HIV) transmission in stable serodiscordant couples in the HPTN-052 study, a resource-intensive randomized controlled trial with near-perfect ART ...
Bärnighausen, Till, De Gruttola, Victor, Harling, Guy, Iwuji, Collins C, Mayer, Kenneth H, Mimiaga, Matthew J, Oldenburg, Catherine E, Pillay, Deenan, Seage III, George R, Tanser, Frank   +9 more
core   +3 more sources