Results 121 to 130 of about 3,080,291 (384)

Thioether Synthesis via the Nickel‐Catalyzed Electrochemical Cross Electrophile Coupling of Aryl/Alkyl Disulfides and Aryl/Alkyl Halides

Advanced Synthesis &Catalysis, EarlyView.
A nickel catalyzed electrochemical cross‐electrophile coupling approach for the base‐free synthesis of (un)symmetric (hetero)aryl and alkyl sulfides from organic halides and disulfides is described. The reaction is broadly applicable and tolerates water and air atmosphere. A formal cross‐electrophile coupling approach enables the base‐free synthesis of
Jona Queder, Gerhard Hilt
wiley   +1 more source

Subclinical myocardial disease by cardiac magnetic resonance imaging and spectroscopy in healthy HIV/Hepatitis C virus-coinfected persons. [PDF]

, 2017
Objective The contribution of hepatitis C virus (HCV) infection to the risk of heart failure in human immunodeficiency virus (HIV)-coinfected persons is unknown.
Ambale-Venkatesh, Bharath, Bluemke, David A, Butt, Adeel A, Chew, Kara W, Currier, Judith S, Horwich, Tamara B, Liao, Diana, Lima, João AC, Liu, Chia-Ying, Paul Finn, J   +9 more
core   +2 more sources

HERV‐K TM Subunit Elicits CD8+ T Cell Anergy and Tumor Immune Evasion via Targeting CD3 Coreceptor ε in AML and PDAC

Advanced Science, EarlyView.
Novel viral immune checkpoint K‐TM subunit is aberrantly expressed in CD8+ T cells and enriched in sera of cancer patients, inducing CD8+ T cell anergy and eliciting potent tumor immune escape in mouse model. Mechanistically, K‐TM directly targets and induces the phosphorylation of CD3ε receptor.
Mengyuan Li, Shuwen Zheng, Qinyuan Gong, Zhaoxing Wu, Wen Lei, Wanyue Cao, Ping Wang, Xuzhao Zhang, Wenbin Qian, Yun Liang, Ying Lu, Fenglin Li, Qi Zhang, Rongzhen Xu   +13 more
wiley   +1 more source

Community attitudes on tuberculosis in Botswana: an opportunity for improving the National Tuberculosis Programme outcomes, 2011

BMC Research Notes, 2018
Objectives The Botswana tuberculosis HIV Knowledge Attitude and Practice study sought to assess knowledge, attitudes and practices of communities on TB and identify sources of their information on this disease and HIV.
Godfrey Musuka, Vonai Teveredzi, Lesego Busang, Innocent Chingombe, Panganai Makadzange, Setshwano Mokgweetsinyana, Ronald Ncube, Julita Maradzika, Carmillo Fungai Chinamasa, Themba Moeti   +9 more
doaj   +1 more source

From Bench to Bedside: Emerging Paradigms in CAR‐T Cell Therapy for Solid Malignancies

Advanced Science, EarlyView.
This review discusses emerging paradigms in CAR‐T cell therapy for solid tumors, emphasizing strategies to overcome therapeutic barriers through synthetic biology, immune engineering, and combinatorial approaches. It highlights advancements in logic gating, modulation of the immune microenvironment, and innovative cell designs, providing valuable ...
Yang Chen, Ran Ren, Lirong Yan, Yu Zhou, Ruokai Sun, Huicong Song, Hongfei Yan, Yongsheng Li   +7 more
wiley   +1 more source

Syphilis serology in HIV-positive and HIV-negative Nigerians: The public health significance [PDF]

, 2006
Syphilis has acquired new potential for morbidity and mortality through association with increased risk for HIV infection. Case-control survey was conducted using Rapid Plasma Reagin test and confirmatory Immunochromatographic test among HIV-positive ...
Alo, Moses, Ariom, Thaddeus, Ogbu, Ogbonnaya, Uneke Jesse, Chigozie   +3 more
core   +1 more source

Prevalence and risk factors of HIV in Faisalabad, Pakistan- A retrospective study [PDF]

, 1969
Muhhamad Arif Mann, Fatma Hussain, Muhhamad Jamil   +2 more
openalex   +1 more source

Variations in Innate Immune Cell Subtypes Correlate with Epigenetic Clocks, Inflammaging and Health Outcomes

Advanced Science, EarlyView.
This study uses a high‐resolution DNA methylation reference panel for 19 immune cell‐types, as well as transcriptomic, metabolomic, and large population cohort data to show that age‐related epigenetic heterogeneity within monocytes correlates with inflammaging, biological age, and all‐causemortality, and does so more strongly than existing monocyte ...
Xiaolong Guo, Josephine A. Robertson, Andrea Aparicio, Kirsten Seale, Qingwen Chen, Anne Richmond, Zhaozhen Du, Mahnoor Sulaiman, Shijie C Zheng, Esteban Ballestar, Charlotte AM Cecil, Bastiaan T Heijmans, Steve Horvath, Varun B. Dwaraka, Jessica Lasky‐Su, Ryan Smith, Riccardo E. Marioni, Andrew E Teschendorff   +17 more
wiley   +1 more source

CLAE: A High‐Fidelity Nanopore Sequencing Strategy for Read‐Level Viral Variant Detection and Environmental RNA Virus Discovery

Advanced Science, EarlyView.
High‐fidelity Nanopore sequencing offers a cost‐effective, portable path to uncovering viral dark matter in complex environments—but suffers from severe read‐length bias, low throughput, and limited accuracy. This study traces these limitations to core biochemical barriers and introduces CLAE, a foundational high‐fidelity platform that enables accurate,
Hannah Yu, Sarah Golconda, Ga‐Eun Lee, Dantong Xue, Guillermo Domínguez‐Huerta, James M. Wainaina, Benjamin Bolduc, Shashanka Murthy, Shihyoung Kim, Seth Faith, Shan‐Lu Liu, Jiyoung Lee, Michael Oglesbee, Matthew B Sullivan, Sanggu Kim   +14 more
wiley   +1 more source

Prevalence and incidence of anal high‐grade squamous intraepithelial lesions in a cohort of cisgender men and transgender women who have sex with men diagnosed and treated during acute HIV acquisition in Bangkok, Thailand

Journal of the International AIDS Society
Introduction Men who have sex with men (MSM), especially those living with HIV, are at an increased risk of anal cancer. The prevalence and incidence of its precursor, anal high‐grade squamous intraepithelial lesions (HSILs), among MSM who started ...
Supanat Thitipatarakorn, Nipat Teeratakulpisarn, Siriporn Nonenoy, Aphakan Klinsukontakul, Sujittra Suriwong, Jirat Makphol, Piranun Hongchookiat, Thanyapat Chaya‐ananchot, Napasawan Chinlaertworasiri, Pravit Mingkwanrungruang, Carlo Sacdalan, Kultida Poltavee, Tippawan Pankam, Stephen J. Kerr, Reshmie Ramautarsing, Donn Colby, Nittaya Phanuphak   +16 more
doaj   +1 more source