Results 131 to 140 of about 3,080,291 (384)

HIV Infection and AIDS in Sub-Saharan Africa: Current Status, Challenges and Opportunities

Open AIDS Journal, 2016
Global trends in HIV infection demonstrate an overall increase in HIV prevalence and substantial declines in AIDS related deaths largely attributable to the survival benefits of antiretroviral treatment.
A. Kharsany, Q. Karim
semanticscholar   +1 more source

NamiRNA‐Enhancer Network: The Changing Era Challenge and Chance of miRNA

Advanced Science, EarlyView.
MiRNAs (miRNAs) regulate diverse biological processes across species. Unlike canonical miRNA‐mediated gene repression, Nuclear Activating miRNAs (NamiRNAs) can efficiently upregulate gene expression by targeting enhancers. This review systematically summarizes recent advances in NamiRNA research, elucidates the theory of NamiRNA‐Enhancer‐mediated Gene ...
Lu Chen, Ying Liang, Hongyan Wei, Mengxing Liu, Jin Wu, Wei Li, Wenxuan Li, Yuxiao Jin, Yinshan Li, Wei Zhao, Min Xiao, Kaicheng Zhou, Shuai Yang, Wenqiang Yu   +13 more
wiley   +1 more source

Scaling up hepatitis C testing and linkage-to-care among people who use drugs: lessons learned from a pilot project implemented at a supervised consumption site

BMC Health Services Research
Background Despite rolling out publicly-funded hepatitis C virus (HCV) treatment across the province of British Columbia (BC), Canada, 35% of people returning positive HCV RNA results in 2020 did not initiate treatment.
Alannah Hannigan, Nandini Krishnan, Kirti Singh, Shannon Bytelaar, Deb Schmitz, Sofia Bartlett, David Hall, Rolando Barrios, Julio S. G. Montaner, Marianne Harris, Mark W. Hull, Kate A. Salters   +11 more
doaj   +1 more source

Carbohydrate, lipid, bone and inflammatory markers in HIV-positive adolescents on antiretroviral therapy and hormonal contraception

Journal of Virus Eradication, 2017
Background: Little is known about the cumulative effect of HIV antiretroviral therapy (ART) and hormonal contraception (HC) on metabolism and inflammation in HIV-positive women.
Nadia Kancheva Landolt, Torsak Bunupuradah, Jullapong Achalapong, Pope Kosalaraksa, Witaya Petdachai, Chaiwat Ngampiyaskul, Sasiwimol Ubolyam, Narukjaporn Thammajaruk, Stephen Kerr, Jintanat Ananworanich   +9 more
doaj   +1 more source

HIV testing and HIV prevention in Sweden [PDF]

BMJ, 1998
HIV testing is central to Sweden's programme of preventing the spread of HIV infection. It has been widely promoted and encouraged on the grounds that once HIV infected people are aware of their serostatus and receive appropriate counselling, they will take the necessary steps to protect their partners.1 This faith in the inclination of citizens to ...
openaire   +2 more sources

Discovery of a Baloxavir‐Inspired Endonuclease Inhibitor That Prevents Herpes Simplex Virus 1 Replication in Cell Culture and In Vivo

Advanced Science, EarlyView.
Current herpesvirus treatments targeting the viral DNA polymerase are limited by toxicities and drug resistance. Novel compounds inhibiting the nuclease activity of the herpes simplex virus 1 (HSV‐1) terminase complex, required for viral genome packaging, have been identified.
Sabina Andreu, Kai Tang, Jiahui Zhou, Gabriel Pino‐Peco, Nerea López‐Carrobles, Raquel Bello‐Morales, Daniel Galdo‐Torres, Lina Zhang, Federico Gago, José Antonio López‐Guerrero, Xinyong Liu, Peng Zhan, Luis Menéndez‐Arias   +12 more
wiley   +1 more source

Trends in HIV prevalence and risk behaviours among men who have sex with men from 2013 to 2017 in Nanjing, China: a consecutive cross-sectional survey. [PDF]

, 2019
OBJECTIVE:To examine the trends of HIV prevalence, risk behaviours and HIV testing among men who have sex with men (MSM) in Nanjing. DESIGN:Five consecutive cross-sectional surveys. SETTING:Nanjing, China.
Detels, Roger, Li, Xin, Liu, Li, Wu, Sushu, Xu, Fei, Xu, Wenjiong, Xu, Yuanyuan, Yan, Hongjing, Zhu, Zhengping   +8 more
core   +1 more source

Identifying HIV infection in South African women: How does a fourth generation HIV rapid test perform?

African Journal of Laboratory Medicine, 2011
Background: HIV rapid tests (RT) play an important role in tackling the HIV pandemic in South Africa. Third generation RT that detect HIV antibodies are currently used to diagnose HIV infection at the point of care.
Kapila Bhowan, Emma Kalk, Sonjiha Khan, Gayle Sherman   +3 more
doaj   +1 more source

Highly Efficient Air Sterilization via Low‐Temperature Interfacial Evaporation in Inductively Heated Superhydrophilic Ferromagnetic Filters

Advanced Science, EarlyView.
The first low‐temperature interfacial evaporation air sterilization technology is presented. It is based on a superhydrophilic ferromagnetic micro/nano‐structured stainless‐steel filter, showing ultra‐efficient inductive heating. This technology has demonstrated over 99.6% of SARS‐CoV‐2 and RSV elimination at temperatures in the 60–80 °C range.
Arnau Fons, Cristina Vaca, Eloi Franco‐Trepat, Aritz Lafuente, José Luis Tajada, Albert Serrà, Jorge Diaz Pedroza, Sandra Franco, Rytis Boreika, Itziar Erkizia, Nuria Izquierdo‐Useros, Alberto López‐Ortega, Eneko Garaio, Maria Jose Esplandiu, Josep Nogues, Borja Sepúlveda   +15 more
wiley   +1 more source

Refractory Status Epilepticus and Therapeutic Uncertainties: a Comprehensive Review on Targeting Neuroinflammation and Rationale for Developing a Platform Trial

Advanced Science, EarlyView.
Refractory status epilepticus (RSE) is a life‐threatening neurological emergency with high rates of death and long‐term disability, but treatments for it are often based on limited evidence. RSE is now understood to involve neuroinflammation, which has led to the exploration of anti‐inflammatory and immunomodulatory agents like Tocilizumab. Traditional
Shanika Samarasekera, Suneesh Thilak, Asha Patel, Prashant Nasa, Zubair Ahmed, Lorraine Jacques, William J. Scotton, Cyril Chacko, Randeep Mullhi, Ruoling Chen, Vikram Patil, Suresh Renukappa, Tonny Veenith   +12 more
wiley   +1 more source