Results 141 to 150 of about 3,080,291 (384)
Characterization of the longitudinal HIV-1 quasispecies evolution in HIV-1 infected individuals co-infected with Mycobacterium tuberculosis [PDF]
One of the earliest and most striking observations made about HIV is the extensive genetic variation that the virus has within individual hosts, particularly in the hypervariable regions of the env gene which is divided into 5 variable regions (V1-V5 ...
Leulebirhan, Tsigereda Biru
core
An unusual IRED platform is reported, enabling efficient DKR via reductive amination without any evolutionary engineering. The system accommodates extremely sterically demanding substrates, including naphthyl and quinoline derivatives, delivering naphthyl‐aryl and quinoline‐aryl amine atropisomers with excellent efficiency and stereocontrol (over 80 ...
Zhichao Ni +7 more
wiley +1 more source
Identification of TPRA1 as a Novel Receptor and Predictive Biomarker for Oncolytic Virus M1
This study identifies transmembrane protein adipocyte‐associated 1 (TPRA1) as a novel receptor for oncolytic virus M1 (OVM). TPRA1's ectodomain binds OVM particles, while its intracellular domain facilitates virus internalization, promoting efficient viral entry.
Linyi Hu +20 more
wiley +1 more source
Punicalagin, a pomegranate molecule, helps the body fight Mycobacterium abscessus. It preferentially boosts interstitial macrophages in the lung, stabilizing mitochondria and switching on the autophagy via SIRT1/FoxO3a, which lowers bacterial load without directly killing bacteria.
Kefan Bi +4 more
wiley +1 more source
A deep learning framework called MolVisGNN is proposed to fuse 3D molecular visual information of drugs with multi‐source features, which proves the importance of 3D molecular visual information of drugs and the advancedness of this model in the field of drug discovery, and provides a reference for how to more comprehensively express small molecule ...
Zimai Zhang +9 more
wiley +1 more source
DPOAE in HIV infected adults [PDF]
HIV infection is associated with impairment of hearing function, at any stage of disease causing complication to the external, middle, inner ear and CNS.
Bhat, Jayashree S, Ranjan, Rajesh
core
Prevention of HIV-1 infection with early antiretroviral therapy
Michael Rayment
semanticscholar +1 more source
A wireless skin‐wound care platform for photothermal‐stem cell‐light (PTSCL) therapy, introduced here, leverages a fully wireless and battery‐free optoelectronic module, gold nanoturf‐mediated photothermal interface, and human adipose‐derived stem cell (hADSC) spheroids to synergistically enhance wound healing.
Jong Uk Kim +17 more
wiley +1 more source

