Results 21 to 30 of about 696,413 (247)

The impact of lookback windows on the prevalence and incidence of chronic diseases among people living with HIV: an exploration in administrative health data in Canada

BMC Medical Research Methodology, 2022
Background We described the impact of different lengths of lookback window (LW), a retrospective time period to observe diagnoses in administrative data, on the prevalence and incidence of eight chronic diseases.
Ni Gusti Ayu Nanditha, Xinzhe Dong, Taylor McLinden, Paul Sereda, Jacek Kopec, Robert S. Hogg, Julio S. G. Montaner, Viviane D. Lima   +7 more
doaj   +1 more source

HIV Superinfection [PDF]

The Journal of Infectious Diseases, 2005
Worldwide, 16 cases of HIV-1 superinfection in humans have been reported since 2002. Superinfection is defined as the reinfection of an individual who already has an established infection with a heterologous HIV strain. Controversy exists surrounding superinfection, because it has implications concerning our understanding of worldwide HIV diversity ...
Davey M, Smith, Douglas D, Richman, Susan J, Little   +2 more
openaire   +2 more sources

Positivity rate, trend and associated risk factors of mother-to-child transmission of HIV among HIV-exposed infants

BMC Pediatrics, 2023
Background Mother-To-Child-Transmission (MTCT) of Human Immunodeficiency Virus (HIV) occurs during pregnancy, delivery and breastfeeding, and cause infection among several new-borns.
Gadissa Gutema, Habteyes Hailu Tola, Dinka Fikadu, Dereje Leta, Birra Bejiga, Jaleta Bulti Tura, Saro Abdella, Hassen Mamo   +7 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Poor post‐exposure prophylaxis completion despite improvements in post‐violence service delivery in 14 PEPFAR‐supported sub‐Saharan African countries, 2018–2023

Journal of the International AIDS Society
Introduction Sexual violence (SV) affects millions globally and has a well‐documented bidirectional association with HIV. Post‐exposure prophylaxis (PEP) is a critical, yet often underutilized, HIV prevention tool in post‐SV care.
Udhayashankar Kanagasabai, Stephanie M. Davis, Viva Thorsen, Emily Rowlinson, Anne Laterra, Jennifer Hegle, Carrine Angumua, Alexandre Ekra, Minlangu Mpingulu, Meklit Getahun, Fikirte Sida, Phumzile Mndzebele, Caroline Kambona, Puleng Ramphalla, Eunice Mtingwi, Wezi Msungama, Meghan Duffy, Bukola Adewumi, Ezeomu Olotu, Jackson Sebeza, Jane Kitalile, Rose Apondi, Carlos Muleya, Meagan Cain   +23 more
doaj   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Nutrition Guidelines for HIV-infected Adults and Children in Southern Africa

Southern African Journal of HIV Medicine, 2007
No abstract available.
D. C. Spencer, C. Harman, T. Naicker, S. Gohre   +3 more
doaj   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Retention in primary care among unstably housed residents of a low-income, inner-city neighborhood with a high prevalence of substance use and related disorders

International Journal for Equity in Health
Introduction Access to and engagement with primary healthcare can be difficult for marginalized low-income populations residing in inner cities in high-income countries.
M. Gumprich, W. Zhang, J. Li, K. Salters, R. Barrios, P. Sereda, C. Stanley, R. Joe, D. Hall, V. Lima, G. Sincraian, A. Marante Changir, R. Parry, C. Fulton, T. Wesseling, J. Montaner, S. Parashar, David M. Moore   +17 more
doaj   +1 more source