Results 71 to 80 of about 3,080,291 (384)

HIV and AIDS

DeckerMed Family Medicine, 2021
In the quarter-century since the first report of AIDS in the United States, HIV infection has spread throughout the population, disproportionately affecting black women, Hispanic women, and men who have sex with men. The prognosis for persons infected with HIV has improved dramatically with the introduction and evolution of highly active antiretroviral
openaire   +1 more source

Adipose Mesenchymal Stem Cell‐Derived Exosomes in Conjunction with Roflumilast Ameliorate Chronic Kidney Disease Through the Modulation of Fibrosis and Inflammation

Advanced Biology, EarlyView.
The novelty of this study showed that the injection of exosomes produced from ADMSCs in combination with Roflumilast poses a more favorable therapeutic outcome for CKD induced by Adriamycin, compared to therapy with exosomes or Roflumilast alone. Roflumilast and exosomes treatment lowered the expression of the apoptotic, fibrotic, and inflammatory ...
Mohamed Ali, Mohamed H. Sherif, Nashwa Barakat, Bassant Yahia, Ahmed A. Shokeir, Basel Sitohy   +5 more
wiley   +1 more source

The art of HIV elimination: past and present science [PDF]

, 2015
Introduction: Remarkable strides have been made in controlling the HIV epidemic, although not enough to achieve epidemic control. More recently, interest in biomedical HIV control approaches has increased, but substantial challenges with the HIV cascade ...
de Oliveira, T., Fisher, M., Lwuji, C.C., McGrath, N., Newell, M.-L., Newport, M., Pillay, D., Porter, K.   +7 more
core   +1 more source

Poxvirus Vectors Activate Human NK and MAIT Cells in a Type I Interferon, IL-18, and Monocyte-Dependent Manner

Journal of Immunology Research
Recombinant poxviruses have been extensively studied as vaccine vectors, yet the specific mechanisms by which they engage the immune system remain incompletely understood.
Kombo F. N’guessan, Zhanna Shubin, Kawthar Machmach, Johan K. Sandberg, Julie A. Ake, Sandhya Vasan, Michael A. Eller, Dominic Paquin-Proulx   +7 more
doaj   +1 more source

Increasing of New CA-MRSA Infections Detected in people living with HIV Who Engage in Chemsex in Barcelona: An Ambispective Study

Infectious Diseases and Therapy, 2023
Introduction There are no data on community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) infections in the context of the chemsex phenomenon.
Lorena De La Mora, Cristina Pitart, Laura Morata, Ainoa Ugarte, María Martinez-Rebollar, Elisa De Lazzari, Andrea Vergara, Jordi Bosch, Ignasi Roca, Maria Piquet, Ana Rodriguez, Montserrat Laguno, Juan Ambrosioni, Berta Torres, Ana González-Cordón, Alexy Inciarte, Alberto Foncillas, Josep Riera, Irene Fuertes, Iván Chivite, Esteban Martinez, José L. Blanco, Alex Soriano, Josep Mallolas   +23 more
doaj   +1 more source

Characteristics, Prevention, and Management of Cardiovascular Disease in People Living With HIV: A Scientific Statement From the American Heart Association.

Circulation, 2019
As early and effective antiretroviral therapy has become more widespread, HIV has transitioned from a progressive, fatal disease to a chronic, manageable disease marked by elevated risk of chronic comorbid diseases, including cardiovascular diseases ...
Matthew J. Feinstein, P. Hsue, L. Benjamin, G. Bloomfield, J. Currier, M. Freiberg, S. Grinspoon, J. Levin, C. Longenecker, W. Post   +9 more
semanticscholar   +1 more source

Consolidate Overview of Ribonucleic Acid Molecular Dynamics: From Molecular Movements to Material Innovations

Advanced Engineering Materials, EarlyView.
Molecular dynamics simulations are advancing the study of ribonucleic acid (RNA) and RNA‐conjugated molecules. These developments include improvements in force fields, long‐timescale dynamics, and coarse‐grained models, addressing limitations and refining methods.
Kanchan Yadav, Iksoo Jang, Jong Bum Lee
wiley   +1 more source

Human Galectin-9 Is a Potent Mediator of HIV Transcription and Reactivation. [PDF]

, 2016
Identifying host immune determinants governing HIV transcription, latency and infectivity in vivo is critical to developing an HIV cure. Based on our recent finding that the host factor p21 regulates HIV transcription during antiretroviral therapy (ART),
Abdel-Mohsen, Mohamed, Chavez, Leonard, Chew, Glen M, Danesh, Ali, Deeks, Steven G, Deng, Xutao, Hirashima, Mitsuomi, Hoh, Rebecca, Keating, Sheila, Lanteri, Marion, Ndhlovu, Lishomwa C, Niki, Toshiro, Norris, Philip J, Pillai, Satish K, Sacha, Jonah B, Samuels, Michael L, Shikuma, Cecilia M, Tandon, Ravi   +17 more
core   +7 more sources

Estimating the Prevalence of HIV and Sexual Behaviors Among the US Transgender Population: A Systematic Review and Meta-Analysis, 2006-2017.

American Journal of Public Health, 2019
BACKGROUND Transgender women (transwomen) in the United States have been shown to have high HIV risk with Black and Hispanic transwomen being particularly vulnerable. Growing research on transgender men (transmen) also shows increased HIV risk and burden,
Jeffrey S. Becasen, Christa L Denard, Mary M. Mullins, Darrel H. Higa, T. Sipe   +4 more
semanticscholar   +1 more source

Synergistic Osteogenesis After Co‐Administration of cmRNAs Encoding BMP‐2 and BMP‐7 Utilizing a Transcript‐Activated Matrix

Advanced Functional Materials, EarlyView.
This study demonstrates that the dual delivery of BMP‐2/‐7 coding cmRNAs for bone healing is demonstrated as feasible, safe, and highly osteogenic. Compared to single BMP‐2 or BMP‐7 cmRNAs, the combination enhances the production of both mineral and organic components of the extracellular matrix when delivered using a collagen‐HA scaffold, supporting ...
Claudia Del Toro Runzer, Joanna M. Sadowska, Nadia Roumans, Christian Plank, Christopher H. Evans, Fergal J. O'Brien, Martijn van Griensven, Elizabeth R. Balmayor   +7 more
wiley   +1 more source