Results 211 to 220 of about 2,450,636 (325)

Nature Inspired Delivery Vehicles for CRISPR‐Based Genome Editing

Small, EarlyView.
The review highlights nature‐inspired nanocarriers for CRISPR delivery, emphasizing viral vectors, extracellular vesicles, liposomes, and lipid nanoparticles. It discusses their roles in improving specificity, minimizing immunogenicity, and overcoming barriers in genome editing. Recent advancements, challenges, and therapeutic applications are explored,
Elizabeth Maria Clarissa, Mamata Karmacharya, Hyunmin Choi, Sumit Kumar, Yoon‐Kyoung Cho   +4 more
wiley   +1 more source

Brief Report: HIV Antibodies Decline During Antiretroviral Therapy but Remain Correlated With HIV DNA and HIV-Specific T-Cell Responses. [PDF]

J Acquir Immune Defic Syndr, 2019
Keating SM, Jones RB, Lalama CM, Bosch RJ, McMahon D, Hampton D, Cyktor J, Eron JJ, Mellors JW, Busch MP, Gandhi RT, ACTG 5321 Team.   +11 more
europepmc   +1 more source

Polyreactivity increases the apparent affinity of anti-HIV antibodies by heteroligation

Nature, 2010
H. Mouquet, J. Scheid, M. Zoller, M. Krogsgaard, R. G. Ott, S. Shukair, M. Artyomov, J. Pietzsch, M. Connors, F. Pereyra, B. Walker, D. Ho, P. Wilson, M. Seaman, H. Eisen, A. Chakraborty, T. Hope, J. Ravetch, H. Wardemann, M. Nussenzweig   +19 more
semanticscholar   +1 more source

Trajectories of medication for opioid use disorder and their impact on HIV testing among people who inject drugs in India: A longitudinal assessment of clinic‐based data

Addiction, Volume 120, Issue 4, Page 745-755, April 2025.
Abstract Aims The aim of this study was to identify longitudinal trajectories of medication for opioid use disorder (MOUD) use throughout 1 year following MOUD initiation and to examine the association of trajectory membership with HIV testing among people who inject drugs in India.
Allison M. McFall, Lakshmi Ganapathi, Mihili P. Gunaratne, Aylur K. Srikrishnan, Conjeevaram K. Vasudevan, Santhanam Anand, Sunil S. Solomon, Shruti H. Mehta, Gregory M. Lucas   +8 more
wiley   +1 more source

The association of methadone use with physical function and frailty among persons who inject drugs

Addiction, EarlyView.
Abstract Background and Aims Persons who inject drugs (PWID) experience a high burden of early‐onset frailty, primarily due to multifactorial causes such as infections (human immunodeficiency virus [HIV], hepatitis C virus [HCV]), substance use, and polypharmacy.
Grace L. Kulik, Hsing‐Yu Hsu, Jacqueline Rudolph, Yutong Jiang, Kristine M. Erlandson, Damani A. Piggott, Shruti Mehta, Jeremy D. Walston, Gregory Kirk, Todd T. Brown, Jing Sun   +10 more
wiley   +1 more source

MAJOR HISTOCOMPATIBILITY COMPLEX CLASS I-ASSOCIATED VACCINE PROTECTION FROM SIMIAN IMMUNODEFICIENCY VIRUS-INFECTED PERIPHERAL-BLOOD CELLS [PDF]

, 1994
Boes, J, Bontrop, RE, Cranage, M, de Vries, P, Dings, M, Dubbes, R, Heeney, JL, Jonker, M, Koornstra, W, Niphuis, H, Norley, S, Osterhaus, A, Otting, N, ten Haaft, P, van Els, C   +14 more
core   +1 more source

Machine Learning‐Based Prediction of Life‐Threatening Complications During Hemodialysis in Hospitalized Patients With Poor General Conditions

Artificial Organs, EarlyView.
A machine learning model using predialysis data predicted sudden events during or after hemodialysis with high accuracy (auROC: 0.889). The key predictors included emergency hospitalization, recent surgery, high heart rate, low albumin levels, and high CRP.
Naotaka Kato, Takeshi Goto, Tomoyuki Ohira, Hirotaka Kinoshita, Kugo Kurokawa, Kouhei Naganuma, Chikako Ohminato, Junko Ogasawara, Shingo Hatakeyama, Yoshihiro Sasaki, Kazuyoshi Hirota, Chikara Ohyama   +11 more
wiley   +1 more source

The Acceptability of Oral Fluid Testing for HIV Antibodies: A Pilot Study in Gay Bars in a Predominantly Rural State

Sexually Transmitted Diseases, 1998
F. Sy, S. Rhodes, Simon T. Choi, D. Drociuk, Amy A Laurent, L. Kettinger   +5 more
semanticscholar   +1 more source

The Paediatric BCG Vaccine Century: From Historical Success to Future Innovations

Acta Paediatrica, EarlyView.
ABSTRACT Aim The tuberculosis (TB) vaccine, Bacille‐Calmette‐Guérin (BCG), protects infants against severe forms of primary TB. Yet, it does not protect against pulmonary reactivation TB in adults. Methods A literature review was conducted between 1st January and 28th February 2025 using PubMed, Google Scholar and reports of the World Health ...
Stefan H. E. Kaufmann
wiley   +1 more source

Human Milk Practices in Swedish Neonatal Units: Results From a Nationwide Survey

Acta Paediatrica, EarlyView.
ABSTRACT Aim The aim of this study was to describe the routines for handling mother's own milk and donor human milk in Swedish neonatal care units related to national guidelines. Methods A web‐based survey of 24 of 38 neonatal units and 19 of 28 human milk banks in Sweden. Results Despite national guidelines, breast milk handling varied widely.
Ylva Thernström Blomqvist, Anna‐My Lund, Fredrik Ahlsson, Jenny Ericson, Charlotta Karlsson, Josefin Lundström, Ingela Sandström, Anna Gustafsson   +7 more
wiley   +1 more source