Results 241 to 250 of about 2,450,636 (325)

SUBDUE‐3: SUB‐urothelial DUrvalumab‐89zirconium injEction; a phase 0 biodistribution study protocol

BJU International, EarlyView.
Kevin G. Keane, Richard Gauci, Roslyn J. Francis, Andrew M. Scott, Cynthia Hawks, Andrisha‐Jade Inderjeeth, Ian D. Davis, Jayne Lim, Andrew Redfern, Dickon Hayne   +9 more
wiley   +1 more source

Artificial lipidation of proteins and peptides: from mechanism to clinical applications

The FEBS Journal, EarlyView.
Artificial lipidation transforms protein and peptide therapeutics by attaching fatty acid chains through reversible or permanent chemical strategies. This biomimetic approach delivers four key therapeutic advantages: extended circulation times (enabling weekly instead of daily dosing), alternative administration routes including oral delivery, precise ...
Jiaming Mu, Emily Vong, Sheiliza Carmali
wiley   +1 more source

Understanding the performance of HIV-1 viral vector vaccines: adenovirus and poxvirus case studies. [PDF]

Front Immunol
Manafi MM, Farzani T, Espinoza N, Ozonoff A, Sabeti PC.   +4 more
europepmc   +1 more source

Behind the scenes: how the EMILIN/Multimerin family shapes the cancer landscape

The FEBS Journal, EarlyView.
The EMILIN/Multimerin family members regulate key hallmarks of cancer—including apoptosis, angiogenesis, metastasis, and tumor microenvironment remodeling. As indicated, their function in immune evasion, drug resistance, and metabolic reprogramming remains largely unexplored.
Evelina Poletto, Naike Casagrande, Emanuele Di Siena, Greta Carobolante, Lucrezia Camicia, Giorgia Schinello, Samanta Muzzin, Enrica Timis, Paola Spessotto, Maurizio Mongiat   +9 more
wiley   +1 more source

Comparison of Immune Responses Elicited by Ad5F35-AEgp145 Alone or in Combination with rMVA-AEgp145. [PDF]

Viruses
Yang J, Ma Q, He X, Li H, Zhang X, Hao Y, Feng X.   +6 more
europepmc   +1 more source

HIV-2 Antibody Measurement [PDF]

, 2020
openaire   +1 more source

HIV PrEP use and unmet need among gay, bisexual and other men who have sex with men in London: An analysis of community cross‐sectional surveys in England 2019–2022

HIV Medicine, EarlyView.
Abstract Objectives In England, HIV pre‐exposure prophylaxis (PrEP) was routinely commissioned at sexual health services from 2020. We compared PrEP use and unmet need among gay, bisexual and other men who have sex with men (GBMSM) in London before (2019) and during (2022) routinely commissioned PrEP and the factors associated with its use.
Flavien Coukan, Dana Ogaz, John Saunders, Gary Murphy, Arham Khawar, Iman Scarlett, Hamish Mohammed, Fiona Burns   +7 more
wiley   +1 more source

Development of an Ultrasensitive ELISA Assay for Evaluating HIV-1 Envelope Glycoprotein as a Marker for Targeted Activator of Cell Kill. [PDF]

Viruses
Wu G, Sardo L, Li Y, Heron SD, Shyong B, Mazur M, Gorman DM, Balibar CJ, Magliaro BC, Leach C, Rush T, Howell BJ.   +11 more
europepmc   +1 more source

Immune non‐response despite effective antiretroviral therapy in people living with HIV: A review of potential mechanisms, biomarkers and therapeutic approaches

HIV Medicine, EarlyView.
Abstract Introduction A proportion of people living with HIV (PLWH) fail to restore their CD4 count or their CD4/CD8 ratio despite effective antiretroviral therapy (ART). PLWH with immune non‐response (INR) are at a higher risk of both AIDS and non‐AIDS events. The underlying mechanisms of INR remain unclear.
Charlotte Silvestre, Antoine Gross, Alain Makinson   +2 more
wiley   +1 more source

Enhanced Clearance of HIV-1 Broadly Neutralizing Antibody VRC07-523-LS During Viremia: Influences on Trial Design and Analysis. [PDF]

Clin Transl Sci
Smith NM, Ho BM, Bar KJ, Gama L, Dziubla G, Koup RA, Pensiero M, Serebryannyy L, Caskey M, Wilkin TJ, Wood TD, Morse GD, Venuto CS, Cha R, Ma Q.   +14 more
europepmc   +1 more source