HIV-1 infection regulates gene expression by altering alternative polyadenylation correlated with CPSF6 and CPSF5 redistribution. [PDF]
Luchsinger C +9 more
europepmc +1 more source
Glycan-reactive antibodies isolated from human HIV-1 vaccine trial participants show broad pathogen cross-reactivity. [PDF]
Jamieson PJ +41 more
europepmc +1 more source
The role of acquired host immunity in periodontal diseases
Abstract The aim of this narrative review is to relate the contribution of European researchers to the complex topic of the host immune system in periodontal disease, focusing on acquired immunity. Other chapters in this volume will address the genetics and autoantibody responses and other forms of immunity to periodontal disease.
Denis F. Kinane +2 more
wiley +1 more source
Mycobacterium tuberculosis PE_PGRS62 Protein Inhibits Type I Interferon Responses to Promote HIV-2 Replication by Directly Interacting With Interferon Regulatory Factor 3. [PDF]
Pan C +7 more
europepmc +1 more source
Pan‐European Fragile Populations Cohort for COVID‐19: What Worked, What Didn't, and Lessons Learned
ABSTRACT The COVID‐19 pandemic exposed the vulnerability of immunocompromised hosts and the scarcity of evidence guiding their management. Within the European Horizon 2020 ORCHESTRA project, a multinational consortium connected existing and new cohorts to harmonize data, laboratory methods, and clinical expertise across fragile populations. The fragile
Beatrice Tazza +11 more
wiley +1 more source
Distinguishing active HIV-1 infection from vaccine-induced seropositivity in HIV vaccine trial participants. [PDF]
Dighe K +10 more
europepmc +1 more source
HHV‐8/KSHV in Solid Organ Transplantation: Current Gaps of Knowledge and Future Directions
Risk mitigation strategies, including donors/recipients screening, DNAemia monitoring in recipients at risk, CNI‐to‐mTOR inhibitors switch, antivirals, and rituximab for KICS, may mitigate the impact of HHV‐8/KSHV infection in SOT. This review provides an update on KICS, identifies research gaps, and summarizes advances in screening and management ...
Alessandra Mularoni +9 more
wiley +1 more source
Challenges in the Vaccination of HIV-Infected Individuals. [PDF]
Sisteré-Oró M +4 more
europepmc +1 more source
Abstract Background and Objective For many blood collection agencies (BCAs), meeting the transfusion needs of people living with sickle cell disease, a genetic condition that causes sickling of red blood cells, is a priority but also a challenge because of a lack of diversity in the donor base.
Jennie Haw +3 more
wiley +1 more source
Toward CAR-B cells for HIV-1 therapy. [PDF]
Yin Y, Farzan M.
europepmc +1 more source

