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'It is scary to pause treatment': perspectives on HIV cure-related research and analytical treatment interruptions from women diagnosed during acute HIV in Durban, South Africa. [PDF]

open access: yesHIV Res Clin Pract
Mthimkhulu D   +17 more
europepmc   +1 more source

Immunological approaches to HIV cure

open access: yesSeminars in Immunology, 2021
Combination antiretroviral therapy (ART) to treat human immunodeficiency virus (HIV) infection has proven remarkably successful - for those who can access and afford it - yet HIV infection persists indefinitely in a reservoir of cells, despite effective ART and despite host antiviral immune responses. An HIV cure is therefore the next aspirational goal
Adam R Ward, R Brad Jones
exaly   +3 more sources
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Barriers to HIV Cure

HLA, 2016
AbstractSince the beginning of the epidemic, more than 70 million people have been infected with human immunodeficiency virus (HIV) and about 38 million have died from acquired immune deficiency syndrome (AIDS)‐related illnesses. While the discovery of highly active antiretroviral therapy (HAART) in the mid 90's has saved millions of lives, a complete ...
Stein, J   +2 more
openaire   +2 more sources

An HIV Cure

JAMA, 2014
The discovery and deployment of antiretroviral therapy (ART) for human immunodeficiency virus (HIV) infection is one of the most extraordinary achievements in recent biomedical history. Between 1996 and 2012, ART averted an estimated 6.6 million AIDS-related deaths worldwide.1 For HIV-infected individuals with access to ART, life expectancy at ...
Anthony S, Fauci   +2 more
openaire   +2 more sources

Strategies for the cure of HIV infection

Enfermedades infecciosas y microbiologia clinica (English ed.), 2019
The disadvantages of the long-term administration of antiretroviral therapy as well as the huge number of affected persons have placed the cure of HIV as a primary goal of Public Health. HIV may persist in the organism by at least four mechanisms: a latently infected cellular reservoir, the persistent replication of HIV in spite of ART, anatomic ...
Jesús, Rodríguez-Muñoz   +1 more
openaire   +2 more sources

Can HIV Be Cured?

Scientific American, 2008
The article discusses the development of a cure for HIV. Drug therapies for HIV are discussed, noting the success of highly active antiretroviral therapy (HAART) in fighting the symptoms of the virus. The therapy's inability to cure HIV is also discussed, mentioning that the virus is able to return in full strength if HAART treatment is interrupted or ...
openaire   +2 more sources

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