Results 141 to 150 of about 314,387 (344)

Infection Risk From Humans and Animals in the Anatomy Laboratory: A Scoping Review

Clinical Anatomy, EarlyView.
ABSTRACT Whole‐body dissection is a cornerstone of anatomy education. During and following the COVID‐19 pandemic, exposure to infectious agents and other risks of dissection were highlighted. To identify potential risks, one must have the data outlining these risks in specific situations.
Margaret A. McNulty, Elizabeth R. Agosto
wiley   +1 more source

Population genetic approaches to estimating the size of the HIV reservoir

Journal of Virus Eradication, 2015
J. Hattori, V. Boltz, W. Shao, M. Kearney, F. Maldarelli   +4 more
doaj   +1 more source

Estimating prevalence of accumulated HIV-1 drug resistance in a cohort of patients on antiretroviral therapy [PDF]

, 2011
WP Bannister, Alessandro Cozzi‐Lepri, Jesper Kjær, B Clotet, Adriano Lazzarin, J.-P. Viard, Gitte Kronborg, Dan Duiculescu, Marek Beniowski, Ladislav Machala, Andrew Phillips, M Losso, Christelle Elias, N Vetter, Robert Zangerle, Igor Karpov, Anna Vassilenko, В. М. Мицура, O. Suetnov, Nathan Clumeck, S. De Wit, M Delforge, Robert Colebunders, Linos Vandekerckhove, Vesna Hadžiosmanović, Kosta Kostov, Josip Begovać, Ladislav Machala, H Rozsypal, Dalibor Sedláček, Jens Nielsen, Gitte Kronborg, Thomas Benfield, MV Larsen, J Gerstoft, Terese L. Katzenstein, BR Hansen, Peter Skinhøj, C. Pedersen, Lars Oestergaard, Kai Zilmer, Jelena Šmidt, Matti Ristola, Christine Katlama, Jean‐Paul Viard, Pierre Marie Girard, J. M. Livrozet, Philippe Vanhems, Christian Pradier, François Dabis, D. Neau, Jürgen K. Rockstroh, Robert L. Schmidt, Jan van Lunzen, Olaf Degen, HJ Stellbrink, S Staszewski, John W. Goethe, J. R. Bogner, G Fätkenheuer, J. Kosmidis, Panagiotis Gargalianos, G. Xylomenos, J. Perdios, George Panos, A. Filandras, E. Karabatsaki, Dénes Bánhegyi, F Mulcahy, Israel Yust, Dianna Turner, Michael Burke, S Pollack, Gamal Hassoun, Shlomo Maayan, Antonio Chiesi, Roberto Esposito, I. Mazeu, Cristina Mussini, Claudio Arici, R. Pristerà, Francesco Mazzotta, Andrea Gabbuti, Vincenzo Vullo, Miriam Lichtner, Antonio Chirianni, E. Montesarchio, Miriam Gargiulo, G. Antonucci, Fabio Iacomi, Pasquale Narciso, Chrysoula Vlassi, Maria Carla Re, Adriano Lazzarin, Renato Finazzi, Massimo Galli, Anna Lisa Ridolfo, Antonella d’Arminio Monforte, Baiba Rozentāle, Indra Zeltiņa   +99 more
openalex   +1 more source

Relationship Between Drug Resistance and Death in HIV-Infected Patients Receiving Antiretroviral Therapy — 7 PLADs, China, 2010−2019 [PDF]

, 2021
Tianhao Zhang, Lingjie Liao, Yiming Shao, Yi Feng, Yuhua Ruan, Hui Xing   +5 more
openalex   +1 more source

CuH‐Catalyzed Asymmetric Desymmetrization of Cyclobutenes via Stereodivergent Hydroamination

ChemistryEurope, EarlyView.
The CuH‐catalyzed stereodivergent hydroamination through asymmetric desymmetrization of cyclobutenes has been achieved, yielding a range of trisubstituted aminocyclobutanes with excellent results. A series of subsequent transformations, including the first asymmetric synthesis of two pharmaceutically active molecules, have been realized, and density ...
Xiang Lei, Peng Luo, Shouang Lan, Wennan Dong, Chao Xu, Jinggong Liu, Shuang Yang, Qi Zhang, Xinqiang Fang   +8 more
wiley   +1 more source

HIV-1 Disease Progression and Drug Resistance Mutations among Children on First-Line Antiretroviral Therapy in Ethiopia [PDF]

, 2023
Yimam Getaneh, Fentabil Getnet, Ning Feng, Abdur Rashid, Lingjie Liao, Yi Feng, Yiming Shao   +6 more
openalex   +1 more source

Cardiovascular‐Kidney‐Metabolic Syndrome in People With HIV: An Emerging Frontier for Clinical Pharmacology

Clinical Pharmacology &Therapeutics, EarlyView.
As antiretroviral therapy (ART) prolongs lifespans, people with HIV (PWH) face a new syndemic: Cardiovascular‐Kidney‐Metabolic (CKM) syndrome. Yet CKM in PWH is poorly characterized. Inflammation, complex pharmacokinetic (PK) alterations, ART‐associated metabolic effects, and gut dysbiosis amplify risk. Managing CKM increases medication burden, thereby
Aaron S. Devanathan, Thomas D. Nolin
wiley   +1 more source

Countering Drug Resistance in the Developing World: An Assessment of Incentives across the Value Chain and Recommendations for Policy Interventions [PDF]

The emergence and spread of drug resistance is draining available resources and threatening our ability to treat infectious diseases in developing countries.
Prashant Yadav
core   +1 more source

Advancing Maternal Health with Long‐Acting Therapeutics: Priorities, Efficacy and Safety Considerations, and Emerging Technologies

Clinical Pharmacology &Therapeutics, EarlyView.
Maternal health remains a critical global concern, particularly in underserved populations and in low‐ and middle‐income countries where access to safe and effective therapeutics is limited. Despite the use of medications by most women during pregnancy, the exclusion of pregnant and lactating women from clinical trials has resulted in significant data ...
Rachel K. Scott, Sharon Nachman, Ethel D. Weld, Rachel Daley, Shakir Atoyebi, Robert Bies, Catriona Waitt, Adeniyi Olagunju   +7 more
wiley   +1 more source

Severity of effect considerations regarding the use of mutation as a toxicological endpoint for risk assessment: A report from the 8th International Workshop on Genotoxicity Testing (IWGT)

Environmental and Molecular Mutagenesis, EarlyView.
Abstract Exposure levels without appreciable human health risk may be determined by dividing a point of departure on a dose–response curve (e.g., benchmark dose) by a composite adjustment factor (AF). An “effect severity” AF (ESAF) is employed in some regulatory contexts.
Barbara L. Parsons, Marc A. Beal, Kerry L. Dearfield, George R. Douglas, Min Gi, B. Bhaskar Gollapudi, Robert H. Heflich, Katsuyoshi Horibata, Michelle Kenyon, Alexandra S. Long, David P. Lovell, Anthony M. Lynch, Meagan B. Myers, Stefan Pfuhler, Alisa Vespa, Andreas Zeller, George E. Johnson, Paul A. White   +17 more
wiley   +1 more source