Results 161 to 170 of about 308,174 (298)

Boron‐10 carriers and their applications in boron neutron capture therapy

Precision Radiation Oncology, EarlyView.
Summary of different types of boron drugs. Abstract Boron neutron capture therapy (BNCT) has emerged as a promising therapeutic modality in cancer treatment, demonstrating the ability to selectively eliminate cancer cells through the 10B(n,α)7Li nuclear reaction with minimal side effects on normal tissues.
Dachao Tang, Mengqi Shi, Zhichen Mao, Weiya Chen, Xiaoling Li, Xiao Yan Zhao, Zhigang Liu, Xiao Xu   +7 more
wiley   +1 more source

Notable transmitted HIV drug resistance among people who inject drugs in Pakistan. [PDF]

J Antimicrob Chemother
Melnychuk S, Thompson LH, Archibald C, Blanchard JF, Emmanuel F, Reza T, Dar N, Sandstrom P, Shaw SY, Becker ML, Cholette F.   +10 more
europepmc   +1 more source

Countering Drug Resistance in the Developing World: An Assessment of Incentives across the Value Chain and Recommendations for Policy Interventions [PDF]

The emergence and spread of drug resistance is draining available resources and threatening our ability to treat infectious diseases in developing countries.
Prashant Yadav
core   +1 more source

AlphaFold2‐Guided Cyclic Peptide Stabilizer Design to Target Protein–Protein Interactions

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT The control and modulation of protein–protein interactions (PPIs) is of central importance for the majority of biological processes and most biomedical applications. Stabilization of PPIs, besides inhibition, is of growing pharmaceutical interest.
Niklas Halbwedl, Martin Zacharias
wiley   +1 more source

Utilizing HIV Proviral DNA to Assess for the Presence of HIV Drug Resistance. [PDF]

Clin Infect Dis
Wensing AM, Charpentier C, Calvez V, Ceccherini-Silberstein F, Günthard HF, Jacobsen DM, Paredes R, Shafer RW, Richman DD.   +8 more
europepmc   +1 more source

Disease Progression Mathematical Modeling With a Case Study on Hepatitis B Virus Infection

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 420-434, March 2025.
ABSTRACT Chronic Hepatitis B presents a significant health and socioeconomic burden. The risk of hepatocellular carcinoma remains elevated although treatments are available. Achieving an optimal treatment regimen necessitates a deep comprehension of the dynamic relationship between the virus and its host across disease states.
Clémence Boivin‐Champeaux, Nieves Velez de Mendizabal, Aksana Jones, Scott Balsitis, Stephan Schmidt, Justin S. Feigelman, Francine Johansson Azeredo   +6 more
wiley   +1 more source

HIV drug resistance amongst children and adolescents with viraemia in Lesotho and Tanzania: a nested analysis in the GIVE MOVE trial. [PDF]

J Antimicrob Chemother
Schönenberger CM, Haenggi K, Ringera IK, Luoga E, Bresser M, Mothobi B, Mokhele K, Sando D, Molatelle M, Thahane L, Mnzava D, Ndege R, Hlasoa MM, Kayembe BP, Muhairwe J, Glass TR, Klimkait T, Weisser M, Labhardt ND, Tschumi N, Brown JA.   +20 more
europepmc   +1 more source

Universal Barriers and Facilitators to Systemic Hepatitis C Care: A Systems‐Informed Qualitative Process Evaluation

Systems Research and Behavioral Science, EarlyView.
ABSTRACT Scaling up hepatitis C virus (HCV) testing and treatment for people who inject drugs (PWID) is essential to achieve HCV elimination. We report a retrospective systems‐informed qualitative process evaluation of HCV care across multiple community‐based settings in a region in Scotland, UK.
Gabriele Vojt, Lawrie Elliott, Hannah E. Family, Sharon J. Hutchinson, Matthew Hickman, John F. Dillon, Paul Flowers   +6 more
wiley   +1 more source

Two cases of possible transmitted HIV drug resistance to all currently available integrase inhibitors, the Netherlands, 2025. [PDF]

Euro Surveill
van Kampen J, Voermans J, Soochit W, Mesplède T, van de Laar T, van der Reijden W, Burger D, Shalev N, van Sighem A, Bezemer D, Jurriaans S, van der Vaart T, de Jong H, van der Valk M.   +13 more
europepmc   +1 more source

Unraveling the Physicochemical Landscape of Organoselenium Compounds in Nanocarrier Systems

The Chemical Record, EarlyView.
Main nanocarriers employed to enhance the bioavailability and transport of organoselenium compounds. The image illustrates the key interaction forces that stabilize these organoselenium species in solution, enabling their application in drug delivery systems, catalysis, photoelectronic devices, and sensing technologies. In recent years, publications on
Romelly Eugenia Rojas Ramírez, Tielle Moraes de Almeida, Daiani Canabarro Leite, Gilson Zeni   +3 more
wiley   +1 more source