Results 171 to 180 of about 314,387 (344)

Artificial intelligence strategies for predicting kinase inhibitor resistance: A comprehensive review of methods, challenges, and future perspectives

Journal of Intelligent Medicine, EarlyView.
Abstract Kinase inhibitors are essential in targeted cancer therapy, yet resistance often emerges through secondary mutations, activation of compensatory signaling pathways, or drug‐efflux mechanisms. Artificial intelligence (AI) provides a workflow‐based strategy rather than a list of unrelated tools for predicting and addressing kinase‐inhibitor ...
Faris Hassan, Mohanad Ali Deifallah, Alaa Zaghloul, Rania Elgohary   +3 more
wiley   +1 more source

Isolated anal tuberculosis presenting as an anal fistula in an immunocompetent child

JPGN Reports, EarlyView.
Abstract Extra‐pulmonary tuberculosis accounts for less than 15% of all tuberculosis cases, while intestinal tuberculosis accounts for less than 1% of extra‐pulmonary forms of the disease. Abdominal organ involvement is more common, but extension to the ano‐perineal region is extremely rare.
Mariam Lagrine, Rabiy Elqadiry, Houda Nassih, Aicha Bourrahouat, Imane Ait Sab   +4 more
wiley   +1 more source

Surveys of Transmitted HIV Drug Resistance in 7 Geographic Regions in China, 2008–2009 [PDF]

, 2012
Lingjie Liao, Hui Xing, Yonghui Dong, Guangming Qin, Yanling Ma, Hongyan Lu, Lin Chen, Lan Zhang, Connie Osborne, Nicole Seguy, Daying Wei, Feng Sun, Juan Yang, Yuhua Ruan, Yiming Shao   +14 more
openalex   +1 more source

Review 2: "Population Dynamics of HIV Drug Resistance among Pre-treatment and Treatment-experienced Persons with HIV during Treatment Scale-up in Uganda: A Population-based Longitudinal Study" [PDF]

, 2023
Michael Pickles
openalex   +1 more source

Data‐Independent Acquisition Mass Spectrometry in Tumor Classification and Cancer Biomarker Research

Mass Spectrometry Reviews, EarlyView.
Abstract Cancer treatment is far from optimal also because current classification systems do not reflect the complex molecular status of the tumor and its phenotype in sufficient detail. To construct molecular tumor classifiers, omics tools provide complex molecular data reflecting many aspects from genotype to phenotype.
Jan Simonik, Petr Lapcik, Pavla Bouchalova, Pavel Bouchal   +3 more
wiley   +1 more source

Programme quality indicators of HIV drug resistance among adolescents in urban versus rural settings of the centre region of Cameroon [PDF]

, 2020
Joseph Fokam, Armanda Nangmo, Carlson Wandum, Désiré Takou, Maria Mercedes Santoro, Anne Esther Njom Nlend, Francis Ndongo Ateba, Paul Koki Ndombo, Nelly Kamgaing, Cedric Kamta, André Essiane, Virginie Lambo, Charles Fokunang, Dora Mbanya, Vittorio Colizzi, Carlo Federico Perno, Alexis Ndjolo   +16 more
openalex   +1 more source

Ocular Motor Abnormalities in Functional Neurological Disorder: A Video‐Oculography Study

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Functional neurological disorders (FND) can include various sensory, motor or cognitive symptoms. Eye movement recordings, measured through video‐oculography, could serve as biomarkers for characterizing these dysfunctions in FND.
Aude Sangare, Astrid de Liège, Bertrand Gaymard, Sophie Rivaud‐Péchoux, Cécilia Bonnet, Evžen Růžička, Jaromír May, Tereza Serranová, Francine Mesrati, Emmanuel Roze, Marie Vidailhet, Céline Louapre, Lionel Naccache, Béatrice Garcin   +13 more
wiley   +1 more source

The Spectrum of Abnormal Tongue Movements: Review of Phenomenology, Etiology, and Differential Diagnosis

Movement Disorders Clinical Practice, EarlyView.
ABSTRACT Background Classifying abnormal tongue movements is challenging due to their varied presentations and limited visibility compared to other body parts. Accurate identification of the phenomenology guides physical examination and can point to specific diagnoses.
Nathaniel Bendahan, Seyed‐Mohammad Fereshtehnejad, Christos Ganos, Emily Swinkin, Anthony E. Lang   +4 more
wiley   +1 more source

Prediction of High Level of Multiple Drug Resistance Mutations in HIV-1 Subtype C Reverse Transcriptase Gene among First Line Antiretroviral-Experienced Virological Failure Patients from North India Using Genotypic and Docking Analysis

, 2013
Jaideep S. Toor
openalex   +1 more source

How conformational changes can affect catalysis, inhibition and drug resistance of enzymes with induced-fit binding mechanism such as the HIV-1 protease [PDF]

, 2013
Thomas R. Weikl, Bahram Hemmateenejad
openalex   +1 more source