Results 271 to 280 of about 314,387 (344)

Exploring the impact of baseline and on‐treatment variables on durability of responses to fostemsavir through weeks 96 and 192 in the phase 3 BRIGHTE study

HIV Medicine, EarlyView.
Abstract Objectives The gp120‐directed attachment inhibitor fostemsavir was effective in people with multidrug‐resistant (MDR) HIV‐1 in the BRIGHTE study. Understanding factors associated with virologic response can help clinicians optimize treatment and identify individuals for fostemsavir‐based regimens.
M. Gartland, X. Wang, Q. Liao, B. Li, F. Du, M. Krystal, A. R. Tenorio, A. Pierce, J. R. Castillo‐Mancilla   +8 more
wiley   +1 more source

HIV Drug Resistance Profile in Clients Experiencing Treatment Failure After the Transition to a Dolutegravir-Based First-Line Antiretroviral Treatment Regimen in Mozambique. [PDF]

Pathogens
Ismael N, Hussein C, Magul C, Inguane H, Couto A, Nhangave A, Muteerwa A, Bonou M, Ramos A, Young PW, Chilundo S, Machekano R, Greenberg L, da Silva J, Bhatt N.   +14 more
europepmc   +1 more source

HIV PrEP use and unmet need among gay, bisexual and other men who have sex with men in London: An analysis of community cross‐sectional surveys in England 2019–2022

HIV Medicine, EarlyView.
Abstract Objectives In England, HIV pre‐exposure prophylaxis (PrEP) was routinely commissioned at sexual health services from 2020. We compared PrEP use and unmet need among gay, bisexual and other men who have sex with men (GBMSM) in London before (2019) and during (2022) routinely commissioned PrEP and the factors associated with its use.
Flavien Coukan, Dana Ogaz, John Saunders, Gary Murphy, Arham Khawar, Iman Scarlett, Hamish Mohammed, Fiona Burns   +7 more
wiley   +1 more source

HIV drug resistance to integrase inhibitors in low- and middle-income countries. [PDF]

Nat Med
Fokam J, Inzaule S, Colizzi V, Perno CF, Kaseya J, Ndembi N.   +5 more
europepmc   +1 more source

Late diagnosis of paediatric HIV infection in high‐income countries: Lessons from the HIV Perinatal Virtual Clinic

HIV Medicine, EarlyView.
Abstract Introduction Timely diagnosis of HIV in children remains a challenge in all settings including low‐prevalence, high‐income countries (HIC). We aimed to characterize the prevalence of late diagnosis, and prior missed diagnostic opportunities among new presentations of paediatric HIV in HIC referred to an international Perinatal Virtual Clinic ...
Carolina Curto, M. Tritzali, A. Bamford, A. C. Bailey, E. G. H. Lyall, N. E. Mackie, N. Tickner, C. Foster, on behalf of the PVC   +8 more
wiley   +1 more source

Portable Nanopore sequencing solution for next-generation HIV drug resistance testing. [PDF]

J Clin Virol
Park SY, Faraci G, Ganesh K, Dubé MP, Lee HY.   +4 more
europepmc   +1 more source

The utility of integrating nanopore sequencing into routine HIV-1 drug resistance surveillance

Daniel Lule Bugembe, Deogratius Ssemwanga, Pontiano Kaleebu, Damien C. Tully   +3 more
openalex   +1 more source

Towards inclusive HIV cure development: Identifying important and acceptable HIV cure attributes and strategies among people with HIV in the Netherlands

HIV Medicine, EarlyView.
Abstract Objectives Initial HIV cure interventions may not meet expert‐defined target product profiles (TPPs; desired treatment attributes). Understanding how people with HIV perceive ideal and likely HIV cure attributes is essential. This study examined which optimal TPP attributes people with HIV consider important and which minimum attributes and ...
Maaike A. J. Noorman, John B. F. de Wit, Tamika A. Marcos, Sarah E. Stutterheim, Thijs Albers, Kai J. Jonas, Chantal Den Daas   +6 more
wiley   +1 more source

Supporting long‐term engagement in HIV clinical care: Learning from the COVID‐19 pandemic

HIV Medicine, EarlyView.
Abstract Objectives SHIELD is a London‐based study of engagement in HIV clinical care during and after the COVID‐19 pandemic. We document the characteristics of service users who either re‐engaged or disengaged with HIV care, together with reflections of HIV clinical service‐providers to inform recommendations that address care retention for the long ...
R. Dhairyawan, Sara Paparini, M. Smuk, S. Sidat, R. Mbewe, Silvia Petretti, V. Martin, S. Dakshina, H. Alexander, T. D. Appleby, K. Childs, M. Bracchi, B. Dragovic, G. Haidari, N. Mackie, I. Reeves, A. Umaipalan, L. J. Waters, J. Anderson, C. M. Orkin   +19 more
wiley   +1 more source

Phylogenetic Network Analyses Reveal the Influence of Transmission Clustering on the Spread of HIV Drug Resistance in Quebec from 2002 to 2022. [PDF]

Viruses
Brenner BG, Ibanescu RI, Oliveira M, Margaillan G, Lebouché B, Thomas R, Baril JG, Lorgeoux RP, Roger M, Routy JP, The Montreal Primary Hiv Infection Phi Cohort Study Group.   +10 more
europepmc   +1 more source