Results 261 to 270 of about 308,174 (298)
Some of the next articles are maybe not open access.
Drug resistant tuberculosis and HIV
Nursing Standard, 1990High frequencies of drug resistant tuberculosis in people who are HIV positive are reported from America.
openaire +2 more sources
Reversibility of HIV Drug Resistance
Science, 2000Using a mathematical model, Blower et al . ([1][1]) predicted the impact of antiretroviral therapy (ART) on future trends in the sexual spread of human immunodeficiency virus (HIV). The model employed Latin hypercube sampling to allow for the high degree of uncertainty in the estimation of ...
openaire +2 more sources
Structural Mechanisms of HIV Drug Resistance
Annual Review of Pharmacology and Toxicology, 1996Antiviral therapy for AIDS has focused on the discovery and design of inhibitors for two main enzyme targets of the human immunodeficiency virus type 1 (HIV)--reverse transcriptase (RT) and protease (PR). Despite several classes of promising new anti-HIV agents, the clinical emergence of drug-resistant variants of HIV has severely limited the long-term
J W, Erickson, S K, Burt
openaire +2 more sources
Transmission of HIV-1 drug resistance
Journal of Clinical Virology, 2004The use of highly-active anti-retroviral therapy (HAART) for treating HIV infections is increasing. Recent studies have demonstrated that HAART is improving both the length and quality of life in HIV-infected patients. Resistant strains of HIV arise when drug adherence is poor.
Julian W, Tang, Deenan, Pillay
openaire +2 more sources
2005
These issues also impact the question of postexposure prophylaxis in the occupational setting; resistance considerations in this context should not be ignored. One special subject, widely practiced at this time, is the use of drugs to prevent mother-to-infant transmission of HIV-1.
Mark A. Wainberg, Bluma G. Brenner
openaire +1 more source
These issues also impact the question of postexposure prophylaxis in the occupational setting; resistance considerations in this context should not be ignored. One special subject, widely practiced at this time, is the use of drugs to prevent mother-to-infant transmission of HIV-1.
Mark A. Wainberg, Bluma G. Brenner
openaire +1 more source
HIV antiviral drug resistance: patient comprehension
AIDS Care, 2010A patient's understanding and use of healthcare information can affect their decisions regarding treatment. Better patient understanding about HIV resistance may improve adherence to therapy, decrease population viral load and extend the use of first-line HIV therapies.
C Sarai, Racey +9 more
openaire +2 more sources
Outsmarting HIV Drug Resistance
Science, 1998AIDS RESEARCHMany AIDS drugs act by interfering with a key HIV enzyme called reverse transcriptase (RT), but eventually the replicating virus mutates into strains whose RT is resistant to the drugs, forcing patients to move on to new drugs or drug combinations. Now a team from Harvard University has obtained an atomic portrait of the enzyme that should
openaire +1 more source
Drug combination foils drug-resistant HIV
Chemical & Engineering News Archive, 1995The human immunodeficiency virus (HIV), which causes AIDS, is adept at rapidly developing resistance to drugs created to combat it. Now researchers have devised a strategy that turns HIV's defense mechanism against the virus. At the Wellcome Research Laboratories in Kent, England, Brendan A. Larder, Sharon D. Kemp, and P.
openaire +1 more source
Avoiding Drug Resistance in HIV Reverse Transcriptase
Chemical Reviews, 2021Philip Tedbury +2 more
exaly