Results 101 to 110 of about 484,489 (312)

Raltegravir 1200 mg once daily versus raltegravir 400 mg twice daily, with tenofovir disoproxil fumarate and emtricitabine, for previously untreated HIV-1 infection: a randomised, double-blind, parallel-group, phase 3, non-inferiority trial [PDF]

, 2017
Pedro Cahn, Richard Kaplan, Paul E. Sax, Kathleen Squires, Jean‐Michel Molina, Anchalee Avihingsanon, Winai Ratanasuwan, Evelin Rojas, Mohammed Rassool, Mark Bloch, Linos Vandekerckhove, Peter Ruane, Yazdan Yazdanpanah, Christine Katlama, Xia Xu, Anthony Rodgers, Lilly East, Larissa Wenning, Sandy Rawlins, Brenda Homony, Peter Sklar, Bach‐Yen Nguyen, Randi Y. Leavitt, Hedy Teppler, PE Cahn, Isabel Cassetti, Marcelo H. Losso, MT Bloch, N Roth, James McMahon, Robert J. Moore, D.P. Smith, Nathan Clumeck, Linos Vanderkerckhove, Bernard E. Van Beers, Michel Moutschen, Jean-Guy Baril, Brian Conway, Fiona Smaill, GHR Smith, Anita Rachlis, Sharon Walmsley, Carlos Enrique Tene Pérez, Marcelo Wolff, M. Lasso, CE Chahin, JD Velez, Otto Sussmann, Jacques Reynes, Christine Katlama, Yazdan Yazdanpanah, Samuel Ferret, J Durant, C Duvivier, Isabelle Poizot‐Martin, F. Ajana, JK Rockstroh, G Faetkanheuer, Stefan Eßer, Hans Jaeger, Olaf Degen, Markus Bickel, J. R. Bogner, Keikawus Arastéh, H Hartl, Albrecht Stoehr, EM Rojas, Eduardo Arathoon, LD Gonzalez, Christian R. Mejía, Eduardo Shahar, Dianna Turner, Idan Levy, Zev Sthoeger, Hila Elinav, Andrea Gori, Antonella d’Arminio Monforte, Giampaolo Perri, Adriano Lazzarin, G Rizzardini, Andrea Antinori, Benedetto Maurizio Celesia, F Maggiolo, TS Chow, CKC Lee, Iskandar Azwa, Mohammad Mustafa, Martin Oyanguren, RA Castillo, L. Hercilla, Carmenchu Echiverri, Fernando Maltêz, JG Saraiva da Cunha, Isabel Neves, Eugénio Teófilo, Rosário Serrão, Ф. И. Нагимова, И. М. Хаертынова, Elena Orlova‐Morozova, Evgeny Voronin   +99 more
openalex   +1 more source

HIV: opportunistic infections.

Clinical evidence, 2003
Clin ...
Ioannidis, J., Wilkinson, D.
openaire   +2 more sources

CD20+FCRL4+ B Cells Activate CD8+ T Cells via MHC‐I Restriction in Nasopharyngeal Carcinoma Anti‐Tumor Immunity

Advanced Science, EarlyView.
CD20⁺FCRL4⁺ B cells in nasopharyngeal carcinoma actively cross‐present exogenous tumor antigens via MHC‐I, enhancing CD8⁺ T‐cell activation, memory formation, and cytotoxicity. IFNγ‐driven WDFY4 upregulation facilitates this process. These findings reveal an unconventional B‐cell–mediated antitumor mechanism and indicate potential relevance to ...
Benjian Zhang, Xiaotian Yuan, Kelei Gao, Bo You, Yaxuan Wang, Lai Meng, Zirong Chen, Shaobing Xie, Yunqing Liu, Zijian Dong, Shumin Xie, Ruohao Fan, Fengjun Wang, Junyi Zhang, Zhihai Xie, Yongzhen Mo, Hua Zhang, Weihong Jiang   +17 more
wiley   +1 more source

SARS-CoV-2 seroprevalence among people living with HIV in the German HIV-1 Seroconverter Cohort, 2020–2022

BMC Infectious Diseases
Objectives People living with HIV (PLWH) are a risk group for severe symptoms and higher mortality during COVID-19. We analyzed the dynamic rise of SARS-CoV-2 seroprevalence induced by coinfections and vaccinations in PLWH in the first three years of the
Oliver Hohn, Karolin Meixenberger, Alexander Volkwein, Kyra Körner, Suheda Icli, Uwe Koppe, Martin Hower, Viviane Bremer, Barbara Gunsenheimer-Bartmeyer, Norbert Bannert, the German HIV-1 Seroconverter Study Group   +10 more
doaj   +1 more source

A Deep Representation Learning Method for Quantitative Immune Defense Function Evaluation and Its Clinical Applications

Advanced Science, EarlyView.
ImmuDef, a novel algorithm to quantitatively evaluate the anti‐infection immune defense function of an individual based on RNA‐seq data via a variational autoencoder (VAE) model. It is validated on 3200+ samples across four immune states with high accuracy. It can serve as a metric for disease severity and prognosis across pathogenic cohorts.
Zhen‐Lin Tan, Tao Luo, Yu Lin, Xiao‐Jun Wu, Wen‐Kang Shen, Jie Chen, Qian Lei, An‐Yuan Guo   +7 more
wiley   +1 more source

Developing a next level integrated genomic surveillance: Advances in the molecular epidemiology of HIV in Germany

International Journal of Medical Microbiology
Advances in the molecular epidemiological studies of the Human Immunodeficiency Virus (HIV) at the Robert Koch Institute (RKI) by laboratory and bioinformatic automation should allow the processing of larger numbers of samples and more comprehensive and ...
Kirsten Hanke, Vera Rykalina, Uwe Koppe, Barbara Gunsenheimer-Bartmeyer, Dagmar Heuer, Karolin Meixenberger   +5 more
doaj   +1 more source

Gut Microbiota Dysbiosis Contributes to the Development of the Constitutional Symptoms in Non-HIV Infected Patients with Mycobacterium Tuberculosis Infection [PDF]

, 2020
Wei‐Juin Su, Shiang‐Fen Huang, Ying‐Ying Yang, F.-D. Wang, Chang‐Phone Fung   +4 more
openalex   +1 more source

Boron Nitride Nanomaterials Trigger Immunomodulatory Effects in Human Broncho‐Epithelial Cells by Modulating Eicosanoid Lipid Signaling

Advanced Science, EarlyView.
This study demonstrates that BNNT exposure disrupts lipid homeostasis in bronchial epithelial cell cultures and activates eicosanoid lipid biosynthesis, producing inflammatory lipid mediators like leukotrienes. These effects are more pronounced in asthmatic cell cultures compared to healthy ones.
Govind Gupta, Jonas Bossart, Sènan Mickael D'Almeida, Luis Augusto Visani de Luna, Christoph Schwärzler, Tingting Fu, Vanesa Ayala‐Nunez, Alexander Gogos, Marija Buljan, Vera M Kissling, Emmanuel Flahaut, Miguel Garcia, Cyrill Bussy, Peter Wick, Tina Buerki‐Thurnherr   +14 more
wiley   +1 more source

Progressive loss of IL-2-expandable HIV-1-specific cytotoxic T lymphocytes during asymptomatic HIV infection [PDF]

, 1998
Xia Jin, Mark R. Wills, J. G. P. Sissons, Andrew Carmichael   +3 more
openalex   +1 more source

Alphaviral Capsid Proteins Inhibit Stress Granule Assembly via Competitive RNA Binding With G3BP1

Advanced Science, EarlyView.
Stress granules exert antiviral functions. This study illustrates a conserved function of alphaviral capsid proteins in modulating stress granules. Oligomerization mediated by a helical motif coupled with a positively charged intrinsically disordered region (IDR) directly competes with G3BP1 for RNA binding, thereby disrupting G3BP1‐RNA liquid–liquid ...
Yun Zhang, Yi Liu, Zhiying Yao, Haolong Lai, Xiaoxin Chen, Ziqiu Wang, Yiqiong Bao, Tingting Li, Xiaoming Zhou, Xiabin Chen, Peiguo Yang   +10 more
wiley   +1 more source