Persistent erythrovirus B19 urinary tract infection in an HIV-positive patient [PDF]
, 2001 Laurids Siig Christensen +2 more
openalex +1 more source
GPCRs in CAR‐T Cell Immunotherapy: Expanding the Target Landscape and Enhancing Therapeutic Efficacy
Advanced Science, EarlyView.Chimeric antigen receptor T cell therapy faces dual challenges of target scarcity and an immunosuppressive microenvironment in solid tumors. This review highlights how G protein‐coupled receptors can serve as both novel targets to expand the therapeutic scope and functional modules to enhance CAR‐T cell efficacy.
Zhuoqun Liu +11 more
wiley +1 more source
Droplet Digital CRISPR for Nucleic Acid Detection
Advanced Science, EarlyView.This review outlines recent advances in droplet digital CRISPR technology for nucleic acid detection, combining CRISPR specificity with droplet digital‐based absolute quantification. It summarizes core principles, amplification‐assisted and amplification‐free strategies, and representative DNA and RNA biomarker applications.
Yang Zhang +4 more
wiley +1 more source
Acute Human Immunodeficiency Virus (HIV) Infection Presenting With Bilateral Interstitial Pneumonia: Case Report and Discussion of Potential HIV-Induced Interstitial Pneumonia [PDF]
, 2017 Anna Maria Peri +9 more
openalex +1 more source
Nanoparticle Immunoadjuvant Complexes Augment Germinal Center Responses to Vaccination
Advanced Science, EarlyView.Scaffolding IL‐21 on the surface of a self‐assembling nanoparticle immunogen drives improved germinal center and humoral immune responses. These nanoparticle immunoadjuvant complexes (NICs) functionally modulate the germinal center driving improved somatic hypermutation and antibody maturation, suggesting this platform has potential utility as a ...
Nicholas J. Tursi +21 more
wiley +1 more source
An in-host model of HIV incorporating latent infection and viral mutation [PDF]
, 2015 Deborah Shutt, Stephen Pankavich
openalex +1 more source
Advanced Science, EarlyView.This target trial emulation in solid organ transplant candidates with obesity and type 2 diabetes evaluates whether pre‐transplant dual therapy with GLP‐1 receptor agonists plus SGLT2 inhibitors is associated with post‐transplant mortality and kidney graft outcomes compared with monotherapy or usual care, using multinational electronic health records ...
Yu‐Nan Huang +7 more
wiley +1 more source
Prevalence and risk factors of detectable HIV viral load among pregnant women with HIV infection seeking antenatal care in Southern Malawi [PDF]
Felix A. Mkandawire +7 more
openalex +1 more source
Infection of Fetal Human Astrocytes by M-Tropic HIV Is Not Inhibited by Prostaglandin-Mediated CCR5 Downregulation [PDF]
, 1999 Nahed Abdel‐Haq +2 more
openalex +1 more source