Results 151 to 160 of about 484,489 (312)

Development of an in situ small intestinal injection technique for targeted macromolecule delivery and in vivo functional studies in mice

Animal Models and Experimental Medicine, EarlyView.
This study developed a minimally invasive, in situ small intestinal injection technique for mice, enabling targeted delivery of bioactive molecules while bypassing gastric degradation. Validation using functional assays and single‐cell RNA sequencing reveals high‐mobility group box 1–mediated epithelial responses, offering a translational tool for gut ...
Yawen Lai, Xintao Zhang, Tingting Luo, Wenhan Chen, Chenyu Ma, Haihua Luo, Jinghua Liu, Jia Xu   +7 more
wiley   +1 more source

Nicotinamide riboside and pterostilbene reduces markers of hepatic inflammation in NAFLD: A double‐blind, placebo‐controlled clinical trial

Hepatology, EarlyView., 2022
NRPT 1X reduces ALT and ceramide 14:0 in 65% of subjects as compared to only 28% in the placebo group. Abstract Background and Aims The prevalence of NAFLD is increasing globally and on a path to becoming the most frequent cause of chronic liver disease. Strategies for the prevention and treatment of NAFLD are urgently needed.
Ryan W. Dellinger, Holly E. Holmes, Tina Hu‐Seliger, Rodney W. Butt, Stephen A. Harrison, Dariush Mozaffarian, Oliver Chen, Leonard Guarente   +7 more
wiley   +1 more source

Geospatial and phylogenetic clustering of acute and recent HIV infections in Lilongwe, Malawi. [PDF]

PLOS Glob Public Health
Bell GJ, Powers KA, Ratmann O, Dennis AM, Mmodzi P, Matoga M, Jere E, Chen JS, Maierhofer CN, Rutstein SE, Lancaster KE, Chagomerana MB, Bonongwe N, Mathiya E, Ndalama B, Bonsall D, Weir SS, Hosseinipour MC, Emch M, Cohen MS, Hoffman IF, Miller WC.   +21 more
europepmc   +1 more source

Epithelial Cells and Fibroblasts from the Human Female Reproductive Tract Accumulate and Release TFV and TAF to Sustain Inhibition of HIV Infection of CD4+ T cells [PDF]

, 2019
Zheng Shen, Marta Rodríguez‐García, Mickey V. Patel, Jack E. Bodwell, Charles R. Wira   +4 more
openalex   +1 more source

Individual and population-level risk factors for new HIV infections among adults in Eastern and Southern Africa. [PDF]

Nat Commun
Slaymaker E, Calvert C, Marston M, Risher K, Imai-Eaton JW, Moorhouse L, Price A, Abdul R, Dube A, Nabukalu D, Obor D, McLean E, Tlhajoane M, Tomlin K, Urassa M, Baisley K, Crampin A, Geubbels E, Gregson S, Herbst K, Kwaro D, Lutalo T, Newton R, Todd J, ALPHA Network.   +24 more
europepmc   +1 more source

A 95% decline in estimated newly acquired HIV infections, Amsterdam, 2010 to 2022. [PDF]

Euro Surveill, 2023
HIV Transmission Elimination AMsterdam (H-TEAM) Initiative.
europepmc   +1 more source

Association of HIV infection with metabolic syndrome among normal or underweight young adults: evidence from the CHART cohort

, 2020
Ruizi Shi, Xiaoxiao Chen, Haijiang Lin, Weiwei Shen, Xiaohui Xu, Bowen Zhu, Xiaoyi Xu, Yingying Ding, Frank Y. Wong, Na He   +9 more
openalex   +2 more sources

Epidemiological and viral characteristics of undiagnosed HIV infections in Botswana [PDF]

BMC Infect Dis, 2022
Bhebhe L, Moyo S, Gaseitsiwe S, Pretorius-Holme M, Yankinda EK, Manyake K, Kgathi C, Mmalane M, Lebelonyane R, Gaolathe T, Bachanas P, Ussery F, Letebele M, Makhema J, Wirth KE, Lockman S, Essex M, Novitsky V, Ragonnet-Cronin M.   +18 more
europepmc   +2 more sources

HIV Infections and Prevention in Women. [PDF]

Clin Obstet Gynecol
Powell AM.
europepmc   +1 more source

Occurrence of Severe Opportunistic Infections in Children Living with HIV Under Regular Follow-Up in Lubumbashi: Associated Factors and Clinical Implications

Astrid, Lokotshe Kanyama, Bijou, Kanku Kazibale, Nathalie, Mbuyamba Mutombo, Jirene, Ndjibu Ebondo, Panshi, Odon Panshi wa, Lukamba, Jerome Nyembo, Dodo, Manda Mukendi, Franck, Kasans Tshinyengo, Emmanuel, Tshibangu Manyonga, Eric, Kasamba Ilunga, Mick, Shongo ya Pongombo, Philomène, Lungu Anzwal   +11 more
openalex   +1 more source