Opportunistic infection as a cause of transient viremia in chronically infected HIV patients under treatment with HAART [PDF]
When highly active antiretroviral therapy is administered for long periods of time to HIV-1 infected patients, most patients achieve viral loads that are ``undetectable'' by standard assay (i.e., HIV-1 RNA $ < 50$ copies/ml). Yet despite exhibiting sustained viral loads below the level of detection, a number of these patients experience unexplained ...
arxiv +1 more source
Incidence of Opportunistic Infections Among Adult HIV Positive People Receiving Co-trimoxazole Prophylaxis [PDF]
In Ethiopia, Co-trimoxazole prophylaxis therapy (CPT) used to prevent opportunistic infections among people living with HIV is the standard of practice; however incidence of opportunistic infection and their predictors are rarely documented in the ...
G, Y. T. (Yihun)+3 more
core +2 more sources
Background Detailed knowledge of the evolutionary potential of polymorphic sites in a viral protein is important for understanding the development of drug resistance in the presence of an inhibitor. We therefore set out to analyse the molecular evolution
Karolin Meixenberger+9 more
doaj +1 more source
A Likelihood Approach to Incorporating Self-Report Data in HIV Recency Classification [PDF]
Estimating new HIV infections is significant yet challenging due to the difficulty in distinguishing between recent and long-term infections. We demonstrate that HIV recency status (recent v.s. long-term) could be determined from the combination of self-report testing history and biomarkers, which are increasingly available in bio-behavioral surveys ...
arxiv
Turing patterns from dynamics of early HIV infection over a two-dimensional surface [PDF]
We have developed a mathematical model for in-host virus dynamics that includes spatial chemotaxis and diffusion across a two dimensional surface representing the vaginal or rectal epithelium at primary HIV infection. A linear stability analysis of the steady state solutions identified conditions for Turing instability pattern formation. We have solved
arxiv +1 more source
Pathophysiology of CD4+ T-Cell Depletion in HIV-1 and HIV-2 Infections
The hall mark of human immunodeficiency virus (HIV) infection is a gradual loss of CD4+ T-cells and imbalance in CD4+ T-cell homeostasis, with progressive impairment of immunity that leads ultimately to death.
K. K. Vidya Vijayan+3 more
semanticscholar +1 more source
A tale of three cities: persisting high HIV prevalence, risk behaviour and undiagnosed infection in community samples of men who have sex with men [PDF]
Objectives: To examine the geographical variations in HIV prevalence (diagnosed and undiagnosed), use of sexual health services, sexually transmitted infections and sexual behaviour in a community sample of men who have sex with men in three cities in ...
Dodds, JP+3 more
core +1 more source
Modeling the dynamics of biomarkers during primary HIV infection taking into account the uncertainty of infection date [PDF]
During primary HIV infection, the kinetics of plasma virus concentrations and CD4+ cell counts is very complex. Parametric and nonparametric models have been suggested for fitting repeated measurements of these markers. Alternatively, mechanistic approaches based on ordinary differential equations have also been proposed.
arxiv +1 more source
Background If national peak Human Immunodeficiency Virus (HIV) prevalence is positively associated with the prevalence of other sexually transmitted infections (STIs) from before or early on in the HIV epidemics this would suggest common underlying ...
Chris Kenyon
doaj +1 more source
Microalbuminuria in HIV infection
Microalbuminuria is associated with increased risk of cardiovascular disease and mortality. The objective of the study was to evaluate if HIV infection was an independent risk factor for microalbuminuria.
Rebecca Scherzer+10 more
openaire +4 more sources