Results 51 to 60 of about 484,489 (312)

Cost-effectiveness of dual maternal HIV and syphilis testing strategies in high and low HIV prevalence countries: a modelling study

The Lancet Global Health, 2021
Summary: Background: Dual HIV and syphilis testing might help to prevent mother-to-child transmission (MTCT) of HIV and syphilis through increased case detection and treatment.
Patricia J Rodriguez, MPH, D Allen Roberts, MPH, Julianne Meisner, BVM&S, Monisha Sharma, PhD, Morkor Newman Owiredu, MBChB, Bertha Gomez, MD, Maeve B Mello, PhD, Alexey Bobrik, MD, Arkadii Vodianyk, MD, Andrew Storey, MBA, George Githuka, MBChB, Thato Chidarikire, PhD, Ruanne Barnabas, DPhil, Magdalena Barr-Dichiara, MPH, Muhammad S Jamil, PhD, Rachel Baggaley, MBBS, Cheryl Johnson, MA, Melanie M Taylor, MD, Alison L Drake, PhD   +18 more
doaj   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

FEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

The Prevalence of HIV by Ethnic Group Is Correlated with HSV-2 and Syphilis Prevalence in Kenya, South Africa, the United Kingdom, and the United States

Interdisciplinary Perspectives on Infectious Diseases, 2014
Background. This paper investigates two issues: do ethnic/racial groups with high HIV prevalences also have higher prevalences of other STIs? and is HIV prevalence by ethnic group correlated with the prevalence of circumcision, concurrency, or having ...
Chris Richard Kenyon, Kara Osbak, Jozefien Buyze   +2 more
doaj   +1 more source

Interleukin‐6 as a Key Biomarker in Facioscapulohumeral Dystrophy: Evidence From Longitudinal Analyses

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy type 1 (FSHD1) is a progressive neuromuscular disorder with no approved treatments. Identifying reliable biomarkers is critical to monitor disease severity, activity, and progression. Interleukin‐6 (IL‐6) has been proposed as a candidate biomarker, but longitudinal validation is limited ...
Jonathan Pini, Emanuela Martinuzzi, Sandra Dhifallah, Abderhmane Slioui, Angela Puma, Luisa Villa, Michele Cavalli, Andra Ezaru, Jérémy Garcia, Manuela Gambella, Federico Torre, Luca Jacopo Pavan, Nicolas Glaichenhaus, Sabrina Sacconi   +13 more
wiley   +1 more source

The Relationship Between Inflammation and Central Nervous System in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Aim Multiple sclerosis is an autoimmune demyelination disease that is seen especially in the young population and has a progressive course, causing motor, sensory, and cognitive deficits. In the literature, the pathogenesis of MS disease and the interconnection between the immune and central nervous system in the disease have not been fully ...
Gamze Ansen, Ali Behram Salar, Abdulkadir Ermis, Erkingul Birday, Lutfu Hanoglu, Bayram Ufuk Sakul   +5 more
wiley   +1 more source

Syphilis in pregnant women living with HIV/AIDS in Brazil and the relationship between coinfection and mother-to-child transmission of HIV

BMC Public Health
Background HIV and syphilis are sexually transmitted infections of concern during pregnancy that affect women and children globally. However, limited data is available regarding the prevalence of syphilis infection among pregnant women living with HIV ...
Mayra Gonçalves Aragón, Leonor Henriette de Lannoy, Pâmela Cristina Gaspar, Ana Paula Betaressi da Silva, Ronaldo de Almeida Coelho, Draurio Barreira, Angélica Espinosa Miranda   +6 more
doaj   +1 more source

A scoping review of media campaign strategies used to reach populations living with or at high risk for Hepatitis C in high income countries to inform future national campaigns in the United Kingdom

BMC Infectious Diseases, 2023
Background With the advent of direct acting antivirals, the World Health Organisation proposed eliminating Hepatitis C as a public health threat by 2030. To achieve this, countries need to diagnose, engage in care and treat their undiagnosed populations.
David Etoori, Monica Desai, Sema Mandal, William Rosenberg, Caroline A Sabin   +4 more
doaj   +1 more source

Portable Low‐Field Magnetic Resonance Imaging in People With Human Immunodeficiency Virus

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The aging population of people with HIV (PWH) raises heightened concerns regarding accelerated aging and dementia. Portable, low‐field MRI (LF‐MRI) is an innovative technology that could enhance access and facilitate routine monitoring of PWH.
Annabel Sorby‐Adams, Malachi Keo, Jennifer Guo, Daire Daly, Richard Ahern, Kimon Zachary, Gregory Robbins, Rajesh T. Gandhi, Bragi Sveinsson, Adam de Havenon, Kevin N. Sheth, Otto Rapalino, Juan Eugenio Iglesias Gonzales, W. Taylor Kimberly, Shibani S. Mukerji   +14 more
wiley   +1 more source

Acceptability and performance of dual HIV/syphilis testing in male circumcision clients, 2021

Southern African Journal of HIV Medicine
Background: Dual HIV/syphilis testing may be an acceptable intervention to identify men with sexually transmitted infections (STIs) and at risk of HIV acquisition.
Tendesayi Kufa, Ocean Tobaiwa, Ewaldé Cutler, Beverley Singh, Zinhle Brukwe, Venessa Maseko, Erushka Pillay, Philip Dorrell, Khumbulani Moyo, Lindokuhle Zondi, Yogan Pillay, Sean Patrick, Adrian Puren   +12 more
doaj   +1 more source