Results 61 to 70 of about 4,398,324 (402)

HIV infection in the elderly

Clinical Interventions in Aging, 2008
In the US, an estimated 1 million people are infected with HIV, although one-third of this population are unaware of their diagnosis. While HIV infection is commonly thought to affect younger adults, there are an increasing number of patients over 50 years of age living with the condition.
Nancy N. Nguyen, Mark Holodniy
openaire   +4 more sources

Mitochondria‐associated membranes (MAMs): molecular organization, cellular functions, and their role in health and disease

FEBS Open Bio, EarlyView.
Mitochondria‐associated membranes (MAMs) are contact sites between the endoplasmic reticulum and mitochondria that regulate calcium signaling, lipid metabolism, autophagy, and stress responses. This review outlines their molecular organization, roles in cellular homeostasis, and how dysfunction drives neurodegeneration, metabolic disease, cancer, and ...
Viet Bui, Maryline Santerre, Natalia Shcherbik, Bassel E Sawaya   +3 more
wiley   +1 more source

Rush to Judgment: The STI-Treatment Trials and HIV in Sub-Saharan Africa

, 2015
Introduction: The extraordinarily high incidence of HIV in sub-Saharan Africa led to the search for cofactor infections that could explain the high rates of transmission in the region.
Akobeng, Anzala, Auvert, Boily, Cartwright, Celum, Celum, Cohen, Deaton, Downs, Eileen Stillwaggon, Estellat, Feldmeier, Fleming, Ghys, Ghys, Ghys, Glynn, Grabowski, Gray, Gray, Gregson, Grosskurth, Grosskurth, Habicht, Harms, Hayes, Hayes, Hayes, Hotez, Hugonnet, Kamali, Kaul, Kaul, Kinzig, Kjetland, Kjetland, Korenromp, Larry Sawers, Larson, Leutscher, Looker, Martin, Modjarrad, Ng, Orroth, Orroth, Orroth, Padian, Pickering, Poggensee, Poggensee, Quigley, R ttingen, Rotchford, Rothman, Rothman, Rothman, Sangani, Schwartz, Schwebke, Sewankambo, Sexton, Stillwaggon, Stillwaggon, Taha, Todd, Victora, Watson-Jones, Watson-Jones, Wawer, WHO, Department of Measurement and Health Information, Wijgert, Wijgert, Wolday, World Health Organization, Worrall   +76 more
core   +2 more sources

Localized spatial clustering of HIV infections in a widely disseminated rural South African epidemic.

International Journal of Epidemiology, 2009
BACKGROUND South Africa contains more than one in seven of the world's HIV-positive population. Knowledge of local variation in levels of HIV infection is important for prioritization of areas for intervention.
F. Tanser, T. Bärnighausen, G. Cooke, M. Newell   +3 more
semanticscholar   +1 more source

Interleukin‐6 as a Key Biomarker in Facioscapulohumeral Dystrophy: Evidence From Longitudinal Analyses

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy type 1 (FSHD1) is a progressive neuromuscular disorder with no approved treatments. Identifying reliable biomarkers is critical to monitor disease severity, activity, and progression. Interleukin‐6 (IL‐6) has been proposed as a candidate biomarker, but longitudinal validation is limited ...
Jonathan Pini, Emanuela Martinuzzi, Sandra Dhifallah, Abderhmane Slioui, Angela Puma, Luisa Villa, Michele Cavalli, Andra Ezaru, Jérémy Garcia, Manuela Gambella, Federico Torre, Luca Jacopo Pavan, Nicolas Glaichenhaus, Sabrina Sacconi   +13 more
wiley   +1 more source

Strategies Used in the Detection of Acute/Early HIV Infections. The NIMH Multisite Acute HIV Infection Study: I

Aids and Behavior, 2009
Acute/early HIV infection plays a critical role in onward HIV transmission. Detection of HIV infections during this period provides an important early opportunity to offer interventions which may prevent further transmission.
P. Kerndt, R. Dubrow, G. Aynalem, K. Mayer, C. Beckwith, R. Remien, Hong M Truong, A. Uniyal, M. Chien, R. Brooks, Ofilio R. Vigil, Wayne T. Steward, M. Merson, M. Rotheram-Borus, S. Morin   +14 more
semanticscholar   +1 more source

Prevalence of HIV, HBV and Chlamydia infections in Cameroonian University context: case of the University of Dschang, in the Western Region [PDF]

, 2015
Introduction: In sub-Saharan Africa HIV infection remains largely epidemic, whereas HBV infection is highly endemic (>8%). In Cameroon, HIV prevalence is 4.3%. Concerning HBV and chlamydia infections, their prevalence are both ≥10%.
Colizzi, V., Djeunang Dongho, G. B., Donfack, J. H., Fokam, J., Mbongue, G., Mpoame, M., Nkamedjie, P. P. M., Onohiol, J. F., Russo, G., Sanou Sobze, M., Watcho, P.   +10 more
core  

Filarial/Human Immunodeficiency Virus Coinfection in Urban Southern India [PDF]

, 2008
The disease course of human immunodeficiency virus (HIV) is often altered by existing or newly acquired coinfections. Treatment or prevention of these concomitant infections often improves the quality and duration of life of HIV-infected persons.
Gopinath, R, Kumaraswamy, N, Nutman, T B, Swaminathan, Soumya, Talaat, KR   +4 more
core   +1 more source

Where, how, and how much? A multicenter cohort study of the relationship between lupus decision aid modality, place of administration, interruption and viewing completeness and patient‐reported outcomes

Arthritis Care &Research, Accepted Article.
Objective We assessed whether shared decision‐making (SDM), and patient acceptability, feasibility, and overall satisfaction with a computerized patient decision aid (PtDA) for patients with systemic lupus erythematosus (SLE), differs by PtDA setting, modality, and the viewing experience.
Jasvinder A. Singh, Mark Beasley, Larry R. Hearld, for the Implementing DEcision‐Aid for Lupus in clinics (IDEAL) Consortium   +3 more
wiley   +1 more source

The Prevalence of HIV by Ethnic Group Is Correlated with HSV-2 and Syphilis Prevalence in Kenya, South Africa, the United Kingdom, and the United States

Interdisciplinary Perspectives on Infectious Diseases, 2014
Background. This paper investigates two issues: do ethnic/racial groups with high HIV prevalences also have higher prevalences of other STIs? and is HIV prevalence by ethnic group correlated with the prevalence of circumcision, concurrency, or having ...
Chris Richard Kenyon, Kara Osbak, Jozefien Buyze   +2 more
doaj   +1 more source