Results 61 to 70 of about 356,037 (312)

Delivery of Islatravir via High Drug‐Load, Long‐acting Microarray Patches for the Prevention or Treatment of Human Immunodeficiency Virus

Advanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.
Islatravir‐loaded dissolving microarray patches (MAPs) provide a minimally invasive, long‐acting solution for HIV‐1 prevention and treatment. In rats, sustained islatravir delivery lasts up to three months, while in minipigs, efficacious plasma levels are detected for six days.
Qonita Kurnia Anjani, Ashley R. Johnson, Akmal H. Sabri, Ryan Lutz, Steven Tignor, Jeanine Ballard, Nathan Rudd, Li Zhao, Lalitkumar K. Vora, Stephanie E. Barrett, Angela Wagner, Ryan F. Donnelly   +11 more
wiley   +1 more source

The Prevalence of HIV by Ethnic Group Is Correlated with HSV-2 and Syphilis Prevalence in Kenya, South Africa, the United Kingdom, and the United States

Interdisciplinary Perspectives on Infectious Diseases, 2014
Background. This paper investigates two issues: do ethnic/racial groups with high HIV prevalences also have higher prevalences of other STIs? and is HIV prevalence by ethnic group correlated with the prevalence of circumcision, concurrency, or having ...
Chris Richard Kenyon, Kara Osbak, Jozefien Buyze   +2 more
doaj   +1 more source

HIV-Infected Patients

Biology of Blood and Marrow Transplantation, 2009
High-dose chemotherapy and autologous stem cell transplantation (SCT) or allogeneic SCT can lead to durable remissions in patients with hematologic malignancies. In the mid-1980s the first studies demonstrating the use of peripheral blood stem cells (PBSC) for autologous transplantation instead of bone marrow (BM) were performed.
openaire   +3 more sources

Engineering CAR‐T Therapeutics for Enhanced Solid Tumor Targeting

Advanced Materials, EarlyView.
CART cell therapy has proven effective for blood cancers but struggles with solid tumors due to diverse antigens and complex environments. Recent efforts focus on improving CAR design and validation platforms. Advances in protein engineering, machine learning, and organoid systems aim to enhance CAR‐T therapy against solid tumors.
Danqing Zhu, Won Joon Kim, Hyunjin Lee, Xiaoping Bao, Pilnam Kim   +4 more
wiley   +1 more source

Prevalence of HIV, HBV and Chlamydia infections in Cameroonian University context: case of the University of Dschang, in the Western Region [PDF]

, 2015
Introduction: In sub-Saharan Africa HIV infection remains largely epidemic, whereas HBV infection is highly endemic (>8%). In Cameroon, HIV prevalence is 4.3%. Concerning HBV and chlamydia infections, their prevalence are both ≥10%.
Colizzi, V., Djeunang Dongho, G. B., Donfack, J. H., Fokam, J., Mbongue, G., Mpoame, M., Nkamedjie, P. P. M., Onohiol, J. F., Russo, G., Sanou Sobze, M., Watcho, P.   +10 more
core  

Is the HCV-HIV co-infection prevalence amongst injecting drug users a marker for the level of sexual and injection related HIV transmission?

, 2013
BACKGROUND: Amongst injecting drug users (IDUs), HIV is transmitted sexually and parenterally, but HCV is transmitted primarily parenterally. We assess and model the antibody prevalence of HCV amongst HIV-infected IDUs (denoted as HCV-HIV co-infection ...
Beattie, Tara, EMCDDA Collaborative Group, Hickman, Matthew, Jarlais, Don Des, Martin, Natasha K, Roy, Anuradha, Strathdee, Steffanie, Vickerman, Peter, Wiessing, Lucas   +8 more
core   +1 more source

HIV-positive nigerian adults harbor significantly higher serum lumefantrine levels than HIV-negative individuals seven days after treatment for Plasmodium falciparum infection. [PDF]

, 2013
Management of coinfection with malaria and HIV is a major challenge to public health in developing countries, and yet potential drug-drug interactions between antimalarial and antiviral regimens have not been adequately investigated in people with both ...
Albert van Wyk, Back, Beshir, Blessborn, Bousema, Byakika-Kibwika, Chijioke Nwauche, Colin J. Sutherland, Dinko, Djimde, Djimdé, Dlamini, Ezzet, Ezzet, Federal Ministry of Health Nigeria, Gerber, Harparkash Kaur, Havlir, Humphreys, Ifeyinwa Chijioke-Nwauche, Khalid B. Beshir, Khoo, Korenromp, Kredo, Lefèvre, McGready, Nwauche, Salman, Sutherland, van Vugt, Whitworth   +30 more
core   +1 more source

The enigma of HIV infection

Cell, 1995
The three reviews that follow this introduction reflect contemporary knowledge of human immunodeficiency virus (HIV) infection and disease induction. Let us take a step back and reflect on why this virus infection, against which 10% of the budget of the National Institutes of Health is deployed, remains so enigmatic. ; © 1995 by Cell Press.
openaire   +4 more sources

Implantable Microarray Patch: Engineering at the Nano and Macro Scale for Sustained Therapeutic Release via Synthetic Biodegradable Polymers

Advanced Materials Technologies, Volume 10, Issue 6, March 18, 2025.
This review focuses on the application of synthetic biodegradable microarray patches (MAPs) in sustained drug delivery. Compared to conventional MAPs which release drugs into the skin in an immediate manner, these implantable MAPs release drugs into skin microcirculation gradually as the biodegradable polymers degrade, thus offering sustained release ...
Li Zhao, Akmal Hidayat Bin Sabri, Mary B. McGuckin, Linlin Li, Zihao Wang, Eneko Larrañeta, Ryan F. Donnelly   +6 more
wiley   +1 more source

Rush to Judgment: The STI-Treatment Trials and HIV in Sub-Saharan Africa

, 2015
Introduction: The extraordinarily high incidence of HIV in sub-Saharan Africa led to the search for cofactor infections that could explain the high rates of transmission in the region.
Akobeng, Anzala, Auvert, Boily, Cartwright, Celum, Celum, Cohen, Deaton, Downs, Eileen Stillwaggon, Estellat, Feldmeier, Fleming, Ghys, Ghys, Ghys, Glynn, Grabowski, Gray, Gray, Gregson, Grosskurth, Grosskurth, Habicht, Harms, Hayes, Hayes, Hayes, Hotez, Hugonnet, Kamali, Kaul, Kaul, Kinzig, Kjetland, Kjetland, Korenromp, Larry Sawers, Larson, Leutscher, Looker, Martin, Modjarrad, Ng, Orroth, Orroth, Orroth, Padian, Pickering, Poggensee, Poggensee, Quigley, R ttingen, Rotchford, Rothman, Rothman, Rothman, Sangani, Schwartz, Schwebke, Sewankambo, Sexton, Stillwaggon, Stillwaggon, Taha, Todd, Victora, Watson-Jones, Watson-Jones, Wawer, WHO, Department of Measurement and Health Information, Wijgert, Wijgert, Wolday, World Health Organization, Worrall   +76 more
core   +2 more sources