Results 91 to 100 of about 22,886 (216)

Inhibition of Adipose Tissue Beiging by HIV Integrase Inhibitors, Dolutegravir and Bictegravir, Is Associated with Adipocyte Hypertrophy, Hypoxia, Elevated Fibrosis, and Insulin Resistance in Simian Adipose Tissue and Human Adipocytes. [PDF]

Cells, 2022
Ngono Ayissi K, Gorwood J, Le Pelletier L, Bourgeois C, Beaupère C, Auclair M, Foresti R, Motterlini R, Atlan M, Barrail-Tran A, Le Grand R, Desjardins D, Fève B, Lambotte O, Capeau J, Béréziat V, Lagathu C.   +16 more
europepmc   +1 more source

HIV-1 integrase inhibitors that compete with the target DNA substrate define a unique strand transfer conformation for integrase [PDF]

, 2000
Amy S. Espeseth, Peter J. Felock, Abigail Wolfe, Marc Witmer, Jay A. Grobler, Neville J. Anthony, Melissa S. Egbertson, Jeffrey Y. Melamed, Steve Young, Terence G. Hamill, James L. Cole, Daria J. Hazuda   +11 more
openalex   +1 more source

Assessment of Integration-defective HIV-1 and EIAV Vectors In Vitro and In Vivo

Molecular Therapy: Nucleic Acids, 2012
The interest in integrase-defective lentiviral vectors (IDLVs) stems from their potential advantage of large cloning capacity and broad cell tropism while avoiding the possibility of insertional mutagenesis.
Scott Ellis, Liang Fong-Wong, Sharifah Iqball, Vinay Thoree, Kyriacos A Mitrophanous, Katie Binley   +5 more
doaj   +1 more source

Degradation of HIV-1 Integrase by the N-end Rule Pathway [PDF]

, 2000
Lubbertus C. F. Mulder, Mark A. Muesing
openalex   +1 more source

Allosteric HIV Integrase Inhibitors Promote Formation of Inactive Branched Polymers via Homomeric Carboxy-Terminal Domain Interactions. [PDF]

Structure, 2021
Gupta K, Allen A, Giraldo C, Eilers G, Sharp R, Hwang Y, Murali H, Cruz K, Janmey P, Bushman F, Van Duyne GD.   +10 more
europepmc   +1 more source

Inhibition of HIV‐1 integrase by modified oligonucleotides derived from U5′ LTR [PDF]

, 2001
Václav Snåšel, Dominik Rejman, Radek Liboska, Z. Točík, Tomáš Ruml, Ivan Rosenberg, Iva Pichová   +6 more
openalex   +1 more source

Potential benefit of dolutegravir once daily: efficacy and safety

HIV/AIDS: Research and Palliative Care, 2013
Alessandra Fantauzzi,1 Ombretta Turriziani,2 Ivano Mezzaroma11Department of Clinical Medicine, 2Department of Molecular Medicine, Sapienza, University of Rome, Rome, ItalyAbstract: The viral integrase enzyme has recently emerged as a primary alternative ...
Fantauzzi A, Turriziani O, Mezzaroma I
doaj  

Structural Biology of HIV Integrase Strand Transfer Inhibitors. [PDF]

Trends Pharmacol Sci, 2020
Jóźwik IK, Passos DO, Lyumkis D.
europepmc   +1 more source

HIV-1 Infection Requires a Functional Integrase NLS [PDF]

, 2001
M. Bouyac-Bertoia, Jeffrey D. Dvorin, Ron A. M. Fouchier, Yonchu Jenkins, Barbara E. Meyer, Lily I. Wu, Michael Emerman, Michael H. Malim   +7 more
openalex   +1 more source

Influence of the amino-terminal sequence on the structure and function of HIV integrase. [PDF]

Retrovirology, 2020
Eilers G, Gupta K, Allen A, Zhou J, Hwang Y, Cory MB, Bushman FD, Van Duyne G.   +7 more
europepmc   +1 more source