Results 91 to 100 of about 26,857 (227)

The Chemical Structures, Neuroprotective Effects, Structure–Activity Relationships, and Applications of Flavonoids, Phenolic Acids, Terpenoids, and Sterols in Dandelion: A Review

Food Science &Nutrition, Volume 14, Issue 6, June 2026.
This review systematically summarizes the chemical structures and structure–activity relationships of key bioactive compounds in dandelion, including flavonoids, phenolic acids, terpenoids, and sterols. It highlights their neuroprotective mechanisms against neuroinflammation and oxidative stress, while outlining their promising dual applications in the
Hongye Li, Bingchan Qu, Jiasu Wu, Menghan Sun, Youlin Xue, Tiejing Li, Chang Tan, Shan Wang, Chong Ning, Chongting Guo   +9 more
wiley   +1 more source

Review of the safety, efficacy, and pharmacokinetics of elvitegravir with an emphasis on resource-limited settings

, 2012
Integrase inhibitors represent an important new class of antiretroviral drugs. Elvitegravir, the second available integrase inhibitor to be submitted for regulatory approval appears to be a promising once-daily agent when combined with other ...
Andrieux-Meyer, Isabelle, Lee, Janice Soo Fern, Calmy, Alexandra, Ford, Nathan   +3 more
core   +1 more source

A Fluorescent Assay to Search for Inhibitors of HIV-1 Integrase Interactions with Human Ku70 Protein, and Its Application for Characterization of Oligonucleotide Inhibitors

Biomolecules, 2020
The search for compounds that can inhibit the interaction of certain viral proteins with their cellular partners is a promising trend in the development of antiviral drugs.
Simon Galkin, Anna Rozina, Arthur Zalevsky, Marina Gottikh, Andrey Anisenko   +4 more
doaj   +1 more source

A Global Health Alert on the Re‐Emergence of Mpox a Viral Zoonotic Illness Its Prevention and Management: A Narrative Review

Health Science Reports, Volume 9, Issue 6, June 2026.
ABSTRACT Background and Aims Monkeypox virus (MPXV) is gaining attention in the global health community due to its potential for human transmission and similarities to the well‐known smallpox virus. Mpox was first detected in the 1970s and mostly affects Central and West Africa.
Muslim Bin Aqeel, Asif Hanif, Shahzad Ahmad, Fatima Iftikhar Shah, Benish Javed, Shazia Iqbal   +5 more
wiley   +1 more source

Timely and Efficient Infant Diagnosis Is Required to End AIDS in Children

Journal of the International AIDS Society, Volume 29, Issue S1, June 2026.
ABSTRACT Introduction Though considerable effort and investment has significantly increased the proportion of pregnant women living with HIV accessing lifesaving antiretroviral therapy and lowered the prevalence of vertical HIV transmission, more than 70,000 children die each year due to AIDS‐related deaths, and nearly half of the 1.4 million children ...
Lara Vojnov, Ilesh V. Jani
wiley   +1 more source

Anti-HIV therapy: pipeline approaches and future directions

, 2011
Human immunodeficiency virus (HIV), with about 30 million deaths and double infections (in developing countries), is an open challenge today for global scientists.
Lavkush Dwivedi, Mansi Shrivastava
core   +1 more source

Baseline Data on Viral Suppression, Treatment Adherence and Mental Health in Peripartum Girls and Young Women With HIV in Zimbabwe

Journal of the International AIDS Society, Volume 29, Issue S1, June 2026.
ABSTRACT Introduction Peripartum adolescent girls and young women (AGYW) with HIV have lower viral suppression compared to older women. But the recently introduced dolutegravir‐based regimens and psychosocial peer motivation may improve viral control.
Tariro D. Chawana‐Mutingwende, Bernard Ngara, Leon‐Say Mudadi, Thelma T. Tauya, Marvelous Sibanda, Mercy Mutambanengwe‐Jacob, Precious Andifasi, Bernadette Malunda, Tinashe Chidemo, Annie Mapfunde, Sandra Nyakudya, Anna Z. Mufumisi, Thandiwe H. Chirenda, Tobias Chitambo, Walter T. S. Nderecha, Constance Murandu, Miriam Gwande, Kudakwashe Muringayi, Rhoda Micah Bongo, Hideaki Okochi, Karen Kuncze, Angela Mushavi, Nicola Willis, Karen Webb, Monica Gandhi, Lynda Stranix‐Chibanda   +25 more
wiley   +1 more source

Prevalence of potential drug-drug interactions in patients of the Swiss HIV cohort study in the era of HIV integrase inhibitors

, 2020
Background: Prevalence of potential drug-drug interactions (PDDIs) between antiretroviral drugs (ARVs) and co-medications was high in 2008 in a Swiss HIV Cohort Study (SHCS) survey.
Battegay, Manuel, Berenguer, J, Young, J., Khoo, Saye, Berenguer, Juan, Marzolini, C., Swiss HIV Cohort Study,, Marzolini, C, Cavassini, M, Battegay, M., Lopez-Centeno, B, Berenguer, J., Khoo, S, Bucher, Heiner C, Calmy, Alexandra, Cipriani, Michela, Jaeckel, S, Calmy, A, Braun, Dominique L, Swiss HIV Cohort Study, Elzi, L, Study, Swiss HIV Cohort, Marzolini, Catia, Scherrer, A, Bucher, HC, Moffa, G, Scherrer, Alexandra U, Elzi, Luigia, Jaeckel, S., Jaeckel, Steffen, Lopez-Centeno, Beatriz, Bucher, Heiner C., Hachfeld, A, Gibbons, Sara, Moffa, G., Battegay, M, Calmy, A., Gibbons, S., Lopez-Centeno, B., Deutschmann, E, Scherrer, Alexandra U., Cavassini, M., McAllister, K, Elzi, L., Young, James, Khoo, S., Deutschmann, Elisabeth, Young, J, Gibbons, S, Cipriani, M., Hachfeld, Anna, Braun, Dominique L., Deutschmann, E., McAllister, Katie, Braun, D.L., Moffa, Giusi, Scherrer, A.U., McAllister, K., Bucher, H.C., Hachfeld, A., Braun, D, Cipriani, M, Cavassini, Matthias   +62 more
core   +1 more source

Resistance against Integrase Strand Transfer Inhibitors and Relevance to HIV Persistence

Viruses, 2015
Drug resistance prevents the successful treatment of HIV-positive individuals by decreasing viral sensitivity to a drug or a class of drugs. In addition to transmitted resistant viruses, treatment-naïve individuals can be confronted with the problem of ...
Thibault Mesplède, Mark A. Wainberg
doaj   +1 more source

Cause of Death and Risk of Death for People Living With HIV Admitted to Hospital: A Systematic Review and Meta‐Analysis

Journal of the International AIDS Society, Volume 29, Issue 6, June 2026.
ABSTRACT Introduction Despite increasing access to HIV treatment and care, HIV‐associated deaths remain high. We aimed to summarize global and regional trends in risk and causes of death among people living with HIV (PLHIV) admitted to hospital. Methods We conducted a systematic search across eight databases on 23 April 2023, identifying studies that ...
Rachael M. Burke, Nadia Sabet, Jayne Ellis, Hannah M. Rickman, Ajay Rangaraj, David S. Lawrence, Joseph N. Jarvis, Jane Falconer, Lillian Tugume, Rebecca H. Berhanu, Nathan Ford, Peter MacPherson   +11 more
wiley   +1 more source