Results 191 to 200 of about 17,322 (222)
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2022
HIV infection is incredibly detrimental and fatal to people. Unfortunately, despite recent advancements and medications, it has not yet been completely eradicated. Opportunistic infections are added to the list of disorders in AIDS (Acquired Immune Deficiency Syndrome), an infectious disease that develops as a result of an impaired immune system.
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HIV infection is incredibly detrimental and fatal to people. Unfortunately, despite recent advancements and medications, it has not yet been completely eradicated. Opportunistic infections are added to the list of disorders in AIDS (Acquired Immune Deficiency Syndrome), an infectious disease that develops as a result of an impaired immune system.
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Integrase Inhibitors Against HIV: Efficacy and Resistance
Future Virology, 2016Divisione Clinicizzata di Malattie Infettive, Dipartimento di Scienze Biomediche e Cliniche ‘Luigi Sacco’, Universita degli Studi di Milano, via G.B. Grassi 74, 20157 Milano, Italy *Author for correspondence: Tel.: +39 02 5031 9761; Fax: +39 02 5031 9758; stefano.rusconi@unimi ...
P. Tau, S. Rusconi
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HIV integrase inhibitors in ART-experienced patients
Current Opinion in HIV and AIDS, 2012We review the most recent clinical trials of integrase inhibitors (INIs) in antiretroviral therapy (ART)-experienced patients, including trails of new strategies such as intensification and simplification therapy with this new class of compounds.After the excellent results of the first-generation INIs [raltegravir (RAL) and elvitegravir] in the ...
Jose-Luis, Blanco +1 more
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HIV integrase inhibitors as therapeutic agents in AIDS
Reviews in Medical Virology, 2007AbstractHIV‐1 integrase is a protein of Mr 32 000 encoded at the 3′‐end of the pol gene. Integration of HIV DNA into the host cell chromosomal DNA apparently occurs by a carefully defined sequence of DNA tailoring (3′‐processing (3′P)) and coupling (integration) reactions.
Vasu, Nair, Guochen, Chi
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Recent Advances in Small-Molecule HIV-1 Integrase Inhibitors
Current Medicinal Chemistry, 2021Chao Zhang, Qian Xie, Zhe Jin
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HIV Integrase Inhibitors and Entry Inhibitors
2021Daniel Bradshaw, Ranjababu Kulasegaram
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Advances in the development of HIV integrase strand transfer inhibitors
European Journal of Medicinal Chemistry, 2021Shuang-Xi Gu, Renhua Fan
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Resistance to HIV-1 integrase inhibitors: A structural perspective
Drug Resistance Updates, 2010Jean-François Mouscadet +2 more
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