Results 101 to 110 of about 651,532 (328)
Advanced Science, EarlyView.This study finds that CD8⁺ TSCM cells exhibit superior self‐renewal, differentiation, and antiviral activity. Transcriptome and epigenome analyses highlight MAPK cascade regulation in TSCM cells. In vivo, virus‐specific TSCM cells show enhanced persistence and tumor protection.
Xun‐Hong Cao +13 more
wiley +1 more source
Virology Journal, 2019 Background Heterosexual transmission has contributed greatly to the current HIV-1 epidemic in China. However, the HIV-1 genetic characteristics in the heterosexually transmitted population in Jiangsu province remained unclear.
Peipei Xiao +11 more
doaj +1 more source
Family Planning and HIV Prevention: Creating Synergies [PDF]
, 2007 Both family planning (FP) and its integration with HIV programs have been overshadowed by donor emphasis on other urgent health issues, namely HIV, malaria and tuberculosis.
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HIV testing and HIV prevention in Sweden [PDF]
BMJ, 1998 HIV testing is central to Sweden's programme of preventing the spread of HIV infection. It has been widely promoted and encouraged on the grounds that once HIV infected people are aware of their serostatus and receive appropriate counselling, they will take the necessary steps to protect their partners.1 This faith in the inclination of citizens to ...
openaire +2 more sources
Astrocytic PERK Deficiency Drives Prefrontal Circuit Dysfunction and Depressive‐Like Behaviors
Advanced Science, EarlyView.Chen et al. show that the endoplasmic reticulum (ER) stress sensor PERK is downregulated in prefrontal cortex (PFC) astrocytes in major depressive disorder and in chronic‐stress mouse models. In young mice, astrocyte‐specific PERK loss reduces the synaptogenic cue thrombospondin‐1 (TSP1), leading to synaptic and circuit deficits and depressive‐like ...
Kai Chen +8 more
wiley +1 more source
The Role of Prevention in Bending the Cost Curve [PDF]
, 2011 Examines how much disease prevention, including those funded in the 2010 healthcare reform law such as diabetes and HIV prevention, smoking cessation, community interventions, and reducing racial/ethnic disparities, can help slow health spending ...
Barbara A. Ormond +2 more
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Advanced Science, EarlyView.Current SARS‐CoV‐2 vaccines generate short‐lived, strain‐specific immunity. A polymeric TLR7 agonist nanoparticle (TLR7‐NP) adjuvant enhances lymph node targeting and promotes early and sustained germinal center responses toward conserved S2 epitopes of the spike protein.
Sijin Huang +12 more
wiley +1 more source
Journal of the International Association of Providers of AIDS Care, 2017 The significance of a gap in HIV care depends, at least partially, on whether patients continue to fill prescriptions for antiretroviral (ARV) drugs during the gap in care.
Kathy K. Byrd MD, MPH +2 more
doaj +1 more source
Health insurance for HIV prevention & treatment: predictors of health insurance enrollment among HIV+ women in Kenya [PDF]
, 2019 Background: The global push to achieve the 90-90-90 targets designed to end the HIV epidemic has called for the removing of policy barriers to prevention and treatment, and ensuring financial sustainability of HIV programs.
Galarraga, Omar +3 more
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Advanced Science, EarlyView.This study identifies a new viral mechanism by a viral protein σ3 that functions as a vTR to suppress NF‐κB gene expression via its direct interaction with the host helicase DHX9. Through their interaction, σ3 not only impairs the initial recruitment of Pol II but also affects Pol II pause‐release and ultimately suppresses NF‐κB gene expression ...
Xueyang Pang +12 more
wiley +1 more source