Results 111 to 120 of about 651,532 (328)

The effect of sexual orientation, gender identity, and marital intention on HIV prevention outcomes among MSM students in Southeast China

open access: yesScientific Reports
Yet studies fail to consider how a lack of concordance among sexual orientation, gender identity, and intent to marry or date a woman hinders the improvement of HIV prevention outcomes.
Lin Chen   +7 more
doaj   +1 more source

Female-initiated prevention: Integrating female condoms into HIV risk-reduction activities in Kenya [PDF]

open access: yes, 2009
The Female Condom (FC) is the only female-initiated prevention product on the market today that provides simultaneous protection against STIs, including HIV, and unintended pregnancy. Despite this unique dual protection benefit, the female condom remains

core  

Flipping the Switch: MeCP2‐Mediated Lactylation Rewires Microglial Metabolism and Inflammation via the HK2/mTOR Axis in Poststroke Neuroinflammation

open access: yesAdvanced Science, EarlyView.
Stroke‐induced lactate accumulation promotes p300‐mediated lactylation of methyl‐CpG binding protein 2 (MeCP2) at lysine 210, which reprograms microglial metabolism toward glycolysis and activates the hexokinase 2 (HK2)/mTOR axis. This cascade promotes proinflammatory responses and impairs neurofunctional outcomes.
Zengyu Zhang   +12 more
wiley   +1 more source

Assessing the Efficiency of Mother-to-Child HIV Prevention in Low- and Middle-Income Countries using Data Envelopment Analysis [PDF]

open access: yes
AIDS is one of the most significant health care problems worldwide. Due to the difficulty and costs involved in treating HIV, preventing infection is of paramount importance in controlling the AIDS epidemic.
Carla A.E. Amado   +2 more
core  

Identification and Characterization of an In Silico Designed Membrane‐Active Peptide with Antiviral Properties

open access: yesAdvanced Science, EarlyView.
An evolutionary molecular dynamics platform is used to design P1.6, a membrane‐active peptide that senses lipid packing defects in viral envelopes. P1.6 adopts a stabilized α‐helical structure upon membrane contact, disrupts virus‐like liposomes, and damages HIV‐1 particles.
Pascal von Maltitz   +10 more
wiley   +1 more source

The determinants of HIV infection and related sexual behaviors : evidence from Lesotho [PDF]

open access: yes
This paper analyzes the socioeconomic determinants of HIV infection and related sexual behaviors using the 2004Lesotho Demographic and Health Survey.
Corno, Lucia, de Walque, Damien
core  

Getting to Zero HIV Cases in San Francisco: Reconceptualizing Housing as Public Health Infrastructure in the Framework of HIV Prevention and Treatment [PDF]

open access: yes, 2019
The City and County of San Francisco, originally ground zero for the HIV epidemic in the United States, is redefining public health HIV interventions, potentially positioning San Francisco as one of the first major metropolitan cities in the world to ...
Zaragoza, Gaspar
core  

Crossing the Blood–Brain Barrier with Molecularly Imprinted Polymeric Nanocarriers: An Emerging Frontier in Brain Disease Therapy

open access: yesAdvanced Science, EarlyView.
Molecularly imprinted polymeric nanocarriers (nanoMIPs) offer robust, antibody‐mimetic platforms to overcome the blood‐brain barrier. The article surveys nanoMIP design and ligand‐directed surface engineering that harness receptor‐mediated transcytosis, and highlights therapeutic and diagnostic applications in neurodegeneration, brain tumors and ...
Ranjit De, Shuliang Shi, Kyong‐Tai Kim
wiley   +1 more source

Poor post‐exposure prophylaxis completion despite improvements in post‐violence service delivery in 14 PEPFAR‐supported sub‐Saharan African countries, 2018–2023

open access: yesJournal of the International AIDS Society
Introduction Sexual violence (SV) affects millions globally and has a well‐documented bidirectional association with HIV. Post‐exposure prophylaxis (PEP) is a critical, yet often underutilized, HIV prevention tool in post‐SV care.
Udhayashankar Kanagasabai   +23 more
doaj   +1 more source

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