Results 101 to 110 of about 2,187,766 (310)

Population pharmacokinetics of levofloxacin in breastmilk in patients with rifampicin‐resistant tuberculosis

British Journal of Clinical Pharmacology, EarlyView.
Levofloxacin is a widely used antibiotic included in rifampicin‐resistant tuberculosis (RR‐TB) treatment. Data describing levofloxacin concentrations in breastmilk and infant exposure are limited. We analysed data from two South African studies of breastfeeding women receiving levofloxacin (750–1000 mg daily) for RR‐TB.
Sharon Sawe, Lufina Tsirizani, Buyisile Mkhize, Lubbe Wiesner, Gary Maartens, Francesca Conradie, Richard Court, Marian Loveday, Catriona Waitt, Paolo Denti   +9 more
wiley   +1 more source

AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury

, 2022
Hepatology, EarlyView.
Robert J. Fontana, Iris Liou, Adrian Reuben, Ayako Suzuki, M. Isabel Fiel, William Lee, Victor Navarro   +6 more
wiley   +1 more source

Zuranolone: A case study in (regulatory) rush to judgement?

British Journal of Clinical Pharmacology, EarlyView.
Abstract Sage, in collaboration with Biogen, submitted a new drug approval for zuranolone for postpartum depression (PPD) and major depressive disorder (MDD) in December 2022. In August 2023, the US Food and Drug Administration granted approval for PPD but denied approval for MDD.
Lisa Cosgrove, Milutin Kostic, Barbara Mintzes, Gianna D'Ambrozio, Allen Shaughnessy   +4 more
wiley   +1 more source

HIV/AIDS in Conflict-Affected Countries, 2024–2025

Journal of Epidemiology and Global Health
Background Conflict reverses development gains and can intensify HIV challenges by driving displacement, poverty, sexual violence, and the collapse of health systems. These conditions may disrupt HIV testing, treatment initiation, and continuity of care.
Shahul H. Ebrahim, Udhayashankar Kanagasabai, Laura N. Broyles, Chantelle Owens, Stephanie Behel   +4 more
doaj   +1 more source

CDC HIV Prevention Progress Report, 2019 [PDF]

cdc-hiv-preventionprogressreport.pdfFrom the Director, Division of HIV/AIDS Prevention -- Report Overview -- Indicator Summaries -- Indicator Data Tables -- Technical Notes -- Selected References ...

core  

HIV prevention while bulldozers roll: developing evidence based HIV prevention intervention for female sex workers following the demolition of Goa’s redlight area [PDF]

, 2010
Background: Interventions targeting female sex workers (FSWs) are pivotal to HIV prevention in India. Societal factors and legislation around sex-work are potential barriers to achieving this. In recent years several high profile closures of red-light
Shahmanesh, M.
core  

Do drugs approved via expedited approval pathways have therapeutic advantages? A systematic review and meta‐analysis

British Journal of Clinical Pharmacology, EarlyView.
Regulators use expedited approval pathways to speed market approval and patient access to promising new drugs. However, there is uncertainty about whether these pathways are successful in approving drugs with significant therapeutic advantages. This systematic review aims to examine the safety, effectiveness and cost‐effectiveness of drugs approved via
Ashleigh Hooimeyer, Eliza J. McEwin, Zhicheng Wang, Joel Lexchin, Barbara Mintzes   +4 more
wiley   +1 more source

Impact of detection rate and preventive treatment of latent tuberculosis infection on the future burden of tuberculosis among students in shanghai: a predictive study using Markov modeling

BMC Public Health
Background Students represent a key demographic for tuberculosis (TB) control in China. This study utilizes a dynamic Markov model to forecast the epidemiological trends of active tuberculosis (ATB) among students in Shanghai through 2035 and evaluate ...
Xiao Xiao, Zhipeng Li, Jing Chen, Xin Shen   +3 more
doaj   +1 more source

Precision medicine in paediatrics: Progress and priorities

British Journal of Clinical Pharmacology, EarlyView.
Precision medicine is revolutionizing personalized healthcare, advancing both diagnostics and therapeutics at an unprecedented pace. Reviewing the paediatric applications of pharmacometrics, pharmacogenomics and advanced therapy medicinal products highlights not only the relevance of these exciting innovations to frontline care but also the significant
Nicola Husain, Claire Booth, Joseph F. Standing, Charlotte I. S. Barker   +3 more
wiley   +1 more source

Analysis of Factors Influencing the Acceptance of Voluntary Counseling and Testing Among Sexually Active College Students in Zhejiang Province, China

HIV/AIDS: Research and Palliative Care
Jiajin He,1,* Xin Zhou,2,* Lingjuan Chen,3 Qiaoqin Ma,2 Liebo Zhu,1 Junfang Lou,1 Lianqi Zha,1 Jieyun Lou,1 Nan Zheng,1 Weiyong Chen2,4 1Yiwu Center for Disease Control and Prevention, Yiwu, Zhejiang, People’s Republic of China ...
He J, Zhou X, Chen L, Ma Q, Zhu L, Lou J, Zha L, Lou J, Zheng N, Chen W   +9 more
doaj