Results 131 to 140 of about 651,532 (328)

Testing trends and co-testing patterns for HIV, hepatitis C and sexually transmitted infections (STIs) in Emergency departments

open access: yesPreventive Medicine Reports
Background: Many underserved populations use Emergency Department (EDs) as primary sources of care, representing an important opportunity to provide infectious disease testing and linkage to care.
Hasan Symum   +10 more
doaj   +1 more source

Effectiveness of Pre‐Transplant Dual GLP‐1 Receptor Agonist and SGLT2 Inhibitor Therapy on All‐Cause Mortality in Organ Transplantation Candidates with Obesity and Type 2 Diabetes: a Target‐Trial Emulation

open access: yesAdvanced Science, EarlyView.
This target trial emulation in solid organ transplant candidates with obesity and type 2 diabetes evaluates whether pre‐transplant dual therapy with GLP‐1 receptor agonists plus SGLT2 inhibitors is associated with post‐transplant mortality and kidney graft outcomes compared with monotherapy or usual care, using multinational electronic health records ...
Yu‐Nan Huang   +7 more
wiley   +1 more source

Analysis of Factors Influencing the Acceptance of Voluntary Counseling and Testing Among Sexually Active College Students in Zhejiang Province, China

open access: yesHIV/AIDS: Research and Palliative Care
Jiajin He,1,* Xin Zhou,2,* Lingjuan Chen,3 Qiaoqin Ma,2 Liebo Zhu,1 Junfang Lou,1 Lianqi Zha,1 Jieyun Lou,1 Nan Zheng,1 Weiyong Chen2,4 1Yiwu Center for Disease Control and Prevention, Yiwu, Zhejiang, People’s Republic of China ...
He J   +9 more
doaj  

Empowerment-based intervention and immigrant awareness of biomedical HIV prevention tools in France [PDF]

open access: gold, 2023
Karna Coulibaly   +9 more
openalex   +1 more source

CD147/Basigin: From Integrative Molecular Hub to Translational Therapeutic Target

open access: yesAdvanced Science, EarlyView.
This review conceptualizes CD147 as a fundamental “Energy‐Structure Coupler,” physically bridging metabolic flux (via MCTs) with morphogenetic plasticity (via integrins/MMPs) to drive cancer, infection, and autoimmunity. Addressing the “specificity paradox” that limits current translation, the authors chart a strategic roadmap—spanning logic‐gated ...
Xiang‐Min Yang   +2 more
wiley   +1 more source

Membralin Assembles a MAN1B1–VCP Complex to Target Foreign Glycoproteins from the Endoplasmic Reticulum to Lysosomes for Degradation

open access: yesAdvanced Science, EarlyView.
This study identifies Membralin as an ER‐phagy receptor that recruits MAN1B1 and VCP to form a selective ERLAD complex. By sensing dense N‐glycan clusters on viral fusion glycoproteins, this ubiquitin‐independent pathway directs SARS‐CoV‐2 spike, Ebola GP, influenza HA, and HIV‐1 Env to lysosomal degradation, thereby limiting viral infectivity ...
Jing Zhang   +5 more
wiley   +1 more source

Disrupting Lipid Raft Microdomains to Block Polyploid Giant Cancer Cell Budding and Enhance Radiotherapy Response

open access: yesAdvanced Science, EarlyView.
Radiation induces polyploid giant cancer cells (PGCCs) that regenerate tumors through virus‐like budding. This process depends on a SNCG–FLOT2–CHMP4B signaling axis functioning in lipid raft microdomains. Disrupting these domains using statins or anti‐PCSK9 antibodies blocks PGCC budding, suppresses tumor repopulation, and enhances radiotherapy ...
Zheng Deng   +20 more
wiley   +1 more source

The costs of HIV prevention for different target populations in Mumbai, Thane and Banglalore [PDF]

open access: gold, 2011
Sudha Chandrashekar   +5 more
openalex   +1 more source

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