Risky Behaviours Among Young People Living with HIV Attending Care and Treatment Clinics in Dar Es Salaam, Tanzania: Implications for Prevention with a Positive Approach. [PDF]
, 2013 Introduction: Prevention with a positive approach has been advocated as one of the main strategies to reduce new instances of HIV infection. Risky sexual behaviours among people living with HIV/AIDS are the cornerstone for this approach.
Leyna, Germana H +2 more
core +2 more sources
SimpactCyan 1.0 : an open-source simulator for individual-based models in HIV epidemiology with R and Python interfaces [PDF]
, 2019 SimpactCyan is an open-source simulator for individual-based models in HIV epidemiology. Its core algorithm is written in C++ for computational efficiency, while the R and Python interfaces aim to make the tool accessible to the fast-growing community of
Delva, Wim +5 more
core +2 more sources
The impact of COVID-19 pandemic on HIV care continuum in Jiangsu, China
BMC Infectious Diseases, 2021 Background The COVID-19 pandemic seriously threatens general public health services globally. This study aimed to evaluate the impact of the COVID-19 pandemic on the HIV care continuum in Jiangsu province, China.
Lingen Shi +8 more
doaj +1 more source
SHIV remission in macaques with early treatment initiation and ultra long-lasting antiviral activity
Nature CommunicationsStudies in SIV-infected macaques show that the virus reservoir is particularly refractory to conventional suppressive antiretroviral therapy (ART). We posit that optimized ART regimens designed to have robust penetration in tissue reservoirs and long ...
Michele B. Daly +16 more
doaj +1 more source
Smarter Programming of the Female Condom: Increasing Its Impact on HIV Prevention in the Developing World [PDF]
, 2008 The purpose of this study was to investigate the relative value of the female condom for HIV prevention within heterosexual relationships in the developing world.
Elliot Marseille +3 more
core
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
EBioMedicineSummary: Background: Current guidelines for post-exposure prophylaxis (PEP) recommend 28 days of daily oral antiretroviral drugs. However, low adherence and inadequate regimen completion represent important challenges.
Priya Srinivasan +15 more
doaj +1 more source
Designing Primary Prevention for People Living with HIV [PDF]
, 2000 Today, there are new reasons for a sharper focus on prevention for people living with HIV. Growing numbers of people with the disease are living more healthy, sexual lives.
Chris Collins +3 more
core
A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins
FEBS Letters, EarlyView.We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue +6 more
wiley +1 more source
"Condoms Are Reliable but I Am Not": A Qualitative Analysis of AIDS-Related Beliefs and Attitudes of Young Heterosexual Adults in Budapest, Hungary and St. Petersburg, Russia [PDF]
, 2006 HIV and STD prevention is an essential component of public health initiatives in countries throughout Central and Eastern Europe. Liberalization in sexual values, declining age at first sex, higher levels of sexual activity, and inconsistent condom use
+19 more
core +1 more source