Results 251 to 260 of about 1,459,292 (318)
HIV-1 Drug Resistance Mutations in Children: A Systematic Review of Global Genotypic Evidence (2014-2026). [PDF]
PathogensJouf G +10 more
europepmc +1 more source
Targeting the AKT pathway: Repositioning HIV protease inhibitors as radiosensitizers.
Indian J Med Res, 2016 Goda JS +4 more
europepmc +1 more source
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New England Journal of Medicine, 1998
Inhibitors of human immunodeficiency virus (HIV)–encoded protease, combined with nucleoside analogues with antiretroviral activity, cause profound and sustained suppression of viral replication, reduce morbidity, and prolong life in patients with HIV infection.1–3 Recent guidelines recommend that initial treatment of all HIV-infected patients include ...
Charles Flexner
exaly +19 more sources
Inhibitors of human immunodeficiency virus (HIV)–encoded protease, combined with nucleoside analogues with antiretroviral activity, cause profound and sustained suppression of viral replication, reduce morbidity, and prolong life in patients with HIV infection.1–3 Recent guidelines recommend that initial treatment of all HIV-infected patients include ...
Charles Flexner
exaly +19 more sources
Current Pharmaceutical Design, 1996
The protease encoded by the human immunodeficiency virus (HIV protease) mediates the maturation of newly formed HIV particles through proteolytic processing of the gag and gag-pol gene products. Because of its essential role in the HIV replication cycle, this enzyme represents a logical target for the treatment of HIV infection.
Hing L Sham, D J Kempf
exaly +14 more sources
The protease encoded by the human immunodeficiency virus (HIV protease) mediates the maturation of newly formed HIV particles through proteolytic processing of the gag and gag-pol gene products. Because of its essential role in the HIV replication cycle, this enzyme represents a logical target for the treatment of HIV infection.
Hing L Sham, D J Kempf
exaly +14 more sources
Fifteen years of HIV Protease Inhibitors: raising the barrier to resistance
Antiviral Research, 2010Monique Nijhuis +2 more
exaly +2 more sources
Hyperlipidemia and inhibitors of HIV protease
Current Opinion in Clinical Nutrition and Metabolic Care, 2001HIV protease inhibitors have been successfully incorporated into therapy for patients with HIV. These otherwise efficacious treatments present with multiple metabolic side-effects and body habitus changes known as the lipodystrophy syndrome. Direct associations of the lipid abnormalities with protease inhibitor use have been described, and ongoing ...
O, Distler +3 more
openaire +2 more sources