ABSTRACT Diabetic foot ulcers (DFUs) are a devastating complication of diabetes that markedly affects quality of life and generates significant socioeconomic and healthcare burdens. When DFUs fail to respond to standard of care (SOC), advanced therapies including Cellular, Acellular and Matrix‐like Products (CAMPs) are often employed. A novel composite
David G. Armstrong +9 more
wiley +1 more source
SARS-CoV-2 Drug-Resistant Mutations in Non-Structural Proteins. [PDF]
Shaw M, Fehr AR.
europepmc +1 more source
Development of a Machine Learning Model to Predict Short Duration HCV Treatment Response
ABSTRACT Standard durations of direct acting antivirals (DAAs; 8–12 weeks) can be a barrier to HCV treatment initiation and completion among marginalized populations. This study developed and internally validated a machine learning model to predict short‐duration (4–6 weeks) DAA response using baseline clinical factors with potential to improve ...
Joanne M. Carson +7 more
wiley +1 more source
Late-stage Diversification of HIV-1 Protease Inhibitor via SuFEx Click Chemistry. [PDF]
Khanal B, Yamanushkin P, Gold B.
europepmc +1 more source
Non-Canonical Binding of Nelfinavir in HIV-1 Protease Variants Reveals Structural Mechanisms of Antiretroviral Resistance. [PDF]
Cadena-Cruz C +11 more
europepmc +1 more source
Novel Bridged Tricyclic Carbamoylpyridone Compounds as HIV Integrase Inhibitors for Treating HIV Infection. [PDF]
Sabnis RW.
europepmc +1 more source
Peptide‐enabled nanoplatforms offer multifunctional strategies for the treatment and diagnosis of malaria and leishmaniasis. Liposomal, polymeric, and metallic nanocarriers, together with cell‐penetrating peptides and parasite‐derived mimotopes, can improve targeted drug delivery, stability, bioavailability, and intracellular localization.
Christian S. Carnero Canales +7 more
wiley +1 more source
Longitudinal Clinical and Molecular Characterization of a Single Pediatric Case of Vertically Acquired HIV-1 Subtype C with Baseline Resistance to Protease Inhibitors. [PDF]
Zaher KA +6 more
europepmc +1 more source
HIV-1 transmitted drug resistance in Shanghai, 2018-2024: population mobility shapes cross-population TDR transmission dynamics. [PDF]
Dong Y +16 more
europepmc +1 more source
The challenge of HTLV-1 therapeutics: lessons from anti-protease approaches. [PDF]
Ahmadi Ghezeldasht S +4 more
europepmc +1 more source

