Results 91 to 100 of about 246,153 (308)
Generation of Mouse iNKT Cell Lines
Bio-Protocol, 2013 Natural killer T (NKT) cells bridge the innate and adaptive arms of the immune system, and manipulating their effector functions can have therapeutic significances in the treatment of autoimmunity, transplant biology, infectious disease and cancer. This
Xiangming Li +3 more
doaj +1 more source
Dynamic pH profiles drive higher cell‐specific and volumetric productivity
Biotechnology Progress, EarlyView.Implementation of dyamic pH profiles for increased CHO cell culture productivity. Abstract Mammalian cell cultures in bioreactors rely heavily on critical process parameter control to ensure optimal growth, productivity, and reproducibility to produce recombinant therapeutic proteins. Culture pH has been shown to be a critical parameter that influences
Stephanie R. Klaubert +6 more
wiley +1 more source
Heterologous prime-boost-boost immunisation of Chinese cynomolgus macaques using DNA and recombinant poxvirus vectors expressing HIV-1 virus-like particles [PDF]
, 2011 Background: There is renewed interest in the development of poxvirus vector-based HIV vaccines due to the protective effect observed with repeated recombinant canarypox priming with gp120 boosting in the recent Thai placebo-controlled trial.
Anson, Donald S. +9 more
core +4 more sources
Infection Risk From Humans and Animals in the Anatomy Laboratory: A Scoping Review
Clinical Anatomy, EarlyView.ABSTRACT Whole‐body dissection is a cornerstone of anatomy education. During and following the COVID‐19 pandemic, exposure to infectious agents and other risks of dissection were highlighted. To identify potential risks, one must have the data outlining these risks in specific situations.
Margaret A. McNulty, Elizabeth R. Agosto
wiley +1 more source
Priming antibody responses to the fusion peptide in rhesus macaques
npj VaccinesImmunodominance of antibodies targeting non-neutralizing epitopes and the high level of somatic hypermutation within germinal centers (GCs) required for most HIV broadly neutralizing antibodies (bnAbs) are major impediments to the development of an ...
Christopher A. Cottrell +20 more
doaj +1 more source
The potential demand for an HIV/AIDS vaccine in Brazil [PDF]
This study assesses the potential demand by the public sector for a preventive HIV/AIDS vaccine in Brazil and the costs of alternative strategies for a vaccination program.
de la Roca Carvalheiro, Jose +5 more
core
ChemistryEurope, EarlyView.Cathepsin B‐sensitive peptide–adjuvant conjugates are designed, synthesized, and evaluated to deliver an antigenic peptid and an adjuvant targeting Toll‐like receptors 7 and 8 (TLR7/8) to antigen presenting cells. The adjuvant is released by cathepsin B resulting in antigen presentation and TLR mediated T cell activation.
Marjolein M. E. Isendoorn +6 more
wiley +1 more source
Therapeutic vaccination against HIV
Expert Review of Vaccines, 2004 The challenge for an immunotherapeutic vaccine is to increase antiviral responses in an increasingly immunocompromised host and to provide immunity to epitopes that have been neglected by the infected host. Therapeutic vaccination with structural and regulatory genes and proteins of HIV are reviewed. The most promising clinical results consist of short-
Britta, Wahren, Margaret, Liu
openaire +2 more sources
The potential demand for and strategic use of an HIV-1 vaccine in Southern India [PDF]
Even a modestly effective HIV-1 vaccine would be highly useful in India and could avoid millions of deaths. How should such a vaccine be introduced? Based on evidence of adoption of other vaccines in India, current levels of spending on them and coverage
Jha, Prabhat +2 more
core
Expression, intracellular targeting and purification of HIV Nef variants in tobacco cells [PDF]
, 2007 Background Plants may represent excellent alternatives to classical heterologous protein expression systems, especially for the production of biopharmaceuticals and vaccine components.
Baschieri , Selene +7 more
core +3 more sources