Results 141 to 150 of about 246,153 (308)

The Two-sample Problem for Failure Rates Depending on a Continuous Mark: An Application to Vaccine Efficacy [PDF]

open access: yes, 2006
The efficacy of an HIV vaccine to prevent infection is likely to depend on the genetic variation of the exposing virus. This paper addresses the problem of using data on the HIV sequences that infect vaccine efficacy trial participants to 1) test for ...
Gilbert, Peter B.   +2 more
core   +1 more source

Leishmania donovani's protein tyrosine phosphatases interact with DUF21 and respond to environmental magnesium

open access: yesThe FEBS Journal, EarlyView.
The Leishmania phosphatase PTP1, and possibly the genetically similar PTP2, interacts with the Leishmania transmembrane protein DUF21. When both ptp1 and ptp2 are knocked out of Leishmania (LdΔPTP1/2), the parasite can no longer survive without magnesium in vitro and has reduced viability in the host macrophage. Conversely, in duf21 knockout (LdΔDUF21),
Kayla Paulini   +6 more
wiley   +1 more source

Protein nanoparticles assemble in plants, display antigenic viral peptides, and produce an epitope‐specific immune response

open access: yesThe FEBS Journal, EarlyView.
Current methods to control porcine reproductive and respiratory syndrome, a disease affecting pigs, are insufficient and a safer, more effective vaccine is needed. This study describes the design and plant production of a self‐assembling protein nanoparticle vaccine candidate against this disease.
Jordan T. VanderBurgt   +5 more
wiley   +1 more source

Programming cytomegalovirus as an HIV vaccine. [PDF]

open access: yesTrends Immunol, 2023
Picker LJ   +4 more
europepmc   +1 more source

Mass‐Standardised Differential Antibody Binding to a Spectrum of SARS‐CoV‐2 Variant Spike Proteins: Wuhan, Alpha, Beta, Gamma, Delta, Omicron BA.1, BA.4/5, BA.2.75 and BA.2.12.1 Variants—Antibody Immunity Endotypes

open access: yesImmunology, EarlyView.
Fully quantitative, mass‐standardised, antibody responses to ten SARS‐CoV‐2 variants show significant variation in immunity profiles or endotypes. The incidence of the complete response to all variants is significantly improved after three vaccinations.
Philip H. James‐Pemberton   +6 more
wiley   +1 more source

SUBDUE‐3: SUB‐urothelial DUrvalumab‐89zirconium injEction; a phase 0 biodistribution study protocol

open access: yes
BJU International, EarlyView.
Kevin G. Keane   +9 more
wiley   +1 more source

Maternity Care Providers Perspectives and Experiences of Obstetric Violence in Low‐, Middle‐ and High‐Income Countries: An Integrative Review

open access: yesJournal of Advanced Nursing, EarlyView.
ABSTRACT Aim To explore the perspectives and experiences of maternity care providers regarding obstetric violence across low‐, middle‐, and high‐income countries. Design An integrative review of the literature. Methods A systematic literature search in CINAHL, Medline (via Ovid), SCOPUS, and the Cochrane Library was conducted from 2014 to 2024. Further
Emma C. Collins   +3 more
wiley   +1 more source

The epidemiological impact of an HIV vaccine on the HIV/AIDS epidemic in Southern India [PDF]

open access: yes
The potential epidemiological impact of preventive HIV vaccines on the HIV epidemic in Southern India is examined using a mathematical deterministic dynamic compartmental model. Various assumptions about the degree of protection offered by such a vaccine,
De Vlas, Sake J., Nagelkerke, Nico J.D.
core  

Time to Hang Up the Gloves: A Scoping Review of Evidence on Non‐Sterile Glove Use During Intravenous Antimicrobial Preparation and Administration

open access: yesJournal of Advanced Nursing, EarlyView.
ABSTRACT Aims To systematically summarise evidence related to the use of non‐sterile gloves when preparing and administering intravenous antimicrobials. Design Scoping review. Methods A rigorous scoping review was undertaken following Arksey and O'Malley's (2005) framework and the modified Preferred Reporting Items for Systematic Reviews and Meta ...
Natasya Raja Azlan   +10 more
wiley   +1 more source

Scoping Review of Sexual and Gender Minority Health Research in Ireland

open access: yesJournal of Advanced Nursing, EarlyView.
ABSTRACT Aim To map existing sexual and gender minority (SGM) health research in Ireland, identify gaps in literature and outline priorities for future research and healthcare. SGM is an umbrella term that includes people who identify as lesbian, gay, bisexual, transgender, queer or intersex and is sometimes abbreviated as LGBTQI+.
John P. Gilmore   +7 more
wiley   +1 more source

Home - About - Disclaimer - Privacy