Results 11 to 20 of about 246,153 (308)

Safety and immunogenicity of H1/IC31®, an adjuvanted TB subunit vaccine, in HIV-infected adults with CD4+ lymphocyte counts greater than 350 cells/mm3: a phase II, multi-centre, double-blind, randomized, placebo-controlled trial. [PDF]

, 2014
BACKGROUND: Novel tuberculosis vaccines should be safe, immunogenic, and effective in various population groups, including HIV-infected individuals. In this phase II multi-centre, double-blind, placebo-controlled trial, the safety and immunogenicity of ...
Andersen, Peter, Bang, Peter, Beattie, Trevor, Churchyard, Gavin J., Daubenberger, Claudia, Fielding, Katherine L., Gardiner, Nicolene, Hanekom, Willem A., Hoff, Søren T., Hughes, Elisabeth J., Jeffery, Hannah, Kagina, Benjamin M., Katsoulis, Lynn, Kromann, Ingrid, Landay, Alan, Lenz, Nicole, Mfinanga, Elirehema, Pohl, Christian, Reither, Klaus, Said, Khadija, Scriba, Thomas J.   +20 more
core   +16 more sources

Novel approaches, including systems biology, to HIV vaccine research and development: Report from a Global HIV Vaccine Enterprise Working Group [PDF]

, 2010
The Global HIV Vaccine Enterprise convened a two-day workshop on August 10-11 2009, at the Fred Hutchison Cancer Research Center offices in Seattle, WA, to discuss the application of novel approaches,including systems biology, to HIV vaccine research and
Alan Aderem, Bali Pulendran, Rino Rappuoli, the Working Group convened by the Global HIV Vaccine Enterprise   +3 more
core   +5 more sources

Neutralization diversity of HIV-1 Indian subtype C envelopes obtained from cross sectional and followed up individuals against broadly neutralizing monoclonal antibodies having distinct gp120 specificities

Retrovirology, 2021
Background The potential use of the broadly neutralizing monoclonal antibodies (bnAbs) towards prophylaxis and treatment to HIV-1 is currently being explored.
Ranajoy Mullick, Jyoti Sutar, Nitin Hingankar, Suprit Deshpande, Madhuri Thakar, Seema Sahay, Rajesh P. Ringe, Sampurna Mukhopadhyay, Ajit Patil, Shubhangi Bichare, Kailapuri G. Murugavel, Aylur K. Srikrishnan, Rajat Goyal, Devin Sok, Jayanta Bhattacharya   +14 more
doaj   +1 more source

Rectal Microbiome Composition Correlates with Humoral Immunity to HIV-1 in Vaccinated Rhesus Macaques. [PDF]

, 2019
The microbiome is an integral and dynamic component of the host and is emerging as a critical determinant of immune responses; however, its influence on vaccine immunogenicity is largely not well understood.
Dinasarapu, Ashok R, Durbin-Johnson, Blythe P, Elizaldi, Sonny R, Iyer, Smita S, Kozlowski, Pamela A, Raeman, Reben, Rolston, Matthew, Settles, Matthew, Verma, Anil, Walter, Korey A   +9 more
core   +1 more source

INTRAPERSONAL FACTORS ASSOCIATED WITH CERVICAL CANCER SCREENING AMONG WOMEN IN FISHING COMMUNITIES OF ENTEBBE MUNICIPALITY, WAKISO DISTRICT. A CROSS-SECTIONAL STUDY.

Student's Journal of Health Research Africa, 2023
Background The chances of developing cervical cancer in Uganda continue to rise especially in the fishing communities due to the relatively higher prevalence of inter-related personal risk factors. This study aimed to examine the Intrapersonal Factors
Emily Keneema , Mathias Lwenge , Zaitune Nanyunja, Barbara Kawoozo, Immaculate Ampeire, Ali Ssetaala, Juliet Mpendo, Brenda Okech, Daniel Okodan   +8 more
doaj   +1 more source

A Trial of a 7-Valent Pneumococcal Conjugate Vaccine in HIV-Infected Adults. [PDF]

, 2010
BACKGROUND: Streptococcus pneumoniae is a leading and serious coinfection in adults with human immunodeficiency virus (HIV) infection, particularly in Africa.
French, N, Gilks, CF, Gordon, SB, Longwe, H, Molyneux, ME, Mwafulirwa, G, Mwaiponya, M, Mwalukomo, T, White, SA, Zijlstra, EE   +9 more
core   +4 more sources

Barriers and Facilitators of Family Planning Use in Fishing Communities of Lake Victoria in Uganda

Journal of Primary Care & Community Health, 2020
Introduction: Family planning (FP) is a key element in the conduct of research and is essential in managing family sizes. Although fishing communities (FCs) are targeted populations for HIV prevention research, their FP practices are poorly understood ...
Annet Nanvubya, Rhoda Kitty Wanyenze, Onesmus Kamacooko, Teddy Nakaweesa, Juliet Mpendo, Barbarah Kawoozo, Francis Matovu, Sarah Nabukalu, Geoffrey Omoding, Jed Kaweesi, John Ndugga, Bernard Bagaya, Kundai Chinyenze, Matt Price, Jean Pierre Van Geertruyden   +14 more
doaj   +1 more source

Cell surface ectodomain integrity of a subset of functional HIV-1 envelopes is dependent on a conserved hydrophilic domain containing region in their C-terminal tail

Retrovirology, 2018
Background HIV-1 Env gp160 is cleaved to form gp120 and gp41 and the functional HIV-1 Env is a trimer of non-covalently associated heterodimeric subunits, gp120 and gp41.
Sweety Samal, Supratik Das, Saikat Boliar, Huma Qureshi, Tripti Shrivastava, Naresh Kumar, Sandeep Goswami, Manish Bansal, Bimal K. Chakrabarti   +8 more
doaj   +1 more source

A randomized trial to assess retention rates using mobile phone reminders versus physical contact tracing in a potential HIV vaccine efficacy population of fishing communities around Lake Victoria, Uganda

BMC Infectious Diseases, 2018
Background High retention (follow-up) rates improve the validity and statistical power of outcomes in longitudinal studies and the effectiveness of programs with prolonged administration of interventions.
Noah Kiwanuka, Juliet Mpendo, Stephen Asiimwe, Julius Ssempiira, Annet Nalutaaya, Betty Nambuusi, Mathias Wambuzi, Brian Kabuubi, Annemarie Namuniina, Frederick Oporia, Annet Nanvubya, Ali Ssetaala   +11 more
doaj   +1 more source

Antenatal Care Practices Among Hard-to-Reach Fishing Communities on Lake Victoria: A Community-Based Cross-Sectional Survey

Journal of Primary Care & Community Health, 2020
Background: Uganda has one of the highest maternal deaths in sub-Saharan Africa, with a mortality ratio of 336 per 100 000 live births. Early regular antenatal care (ANC) helps prevent adverse outcomes, including deaths, through prevention ...
Ali Ssetaala, Joan Nabawanuka, Gideon Matovu, Nusula Nakiragga, Judith Namugga, Phiona Nalubega, Henry Lutalo Kaluuma, Katrina Perehudoff, Kristien Michielsen, Bernard Bagaya, Noah Kiwanuka, Olivier Degomme   +11 more
doaj   +1 more source