Results 231 to 240 of about 246,153 (308)

Epstein–Barr Virus and Hepatitis E Virus in an Immunocompetent Adult: A Rare Case Report

Clinical Case Reports, Volume 14, Issue 2, February 2026.
ABSTRACT Epstein–Barr virus (EBV) and Hepatitis E virus (HEV) are two distinct viral pathogens known to affect the liver. While EBV commonly causes mild, self‐limited hepatitis, and HEV is the leading cause of acute viral hepatitis globally, co‐infection with both viruses is exceedingly rare.
Philippe Attieh, Antonio Al Hazzouri, Karam Karam, Ihab I. El Hajj, Elias Fiani   +4 more
wiley   +1 more source

A polyvalent DNA prime with matched polyvalent protein/GLA-SE boost regimen elicited the most robust and broad IgG and IgG3 V1V2 binding antibody and CD4+ T cell responses among 13 HIV vaccine trials. [PDF]

Emerg Microbes Infect
Moodie Z, Li SS, Giorgi EE, Williams LD, Dintwe O, Carpp LN, Chen S, Seaton KE, Sawant SS, Zhang L, Heptinstall J, Liu S, Grunenberg N, Tomaka F, Rerks-Ngarm S, Pitisuttithum P, Nitayaphan S, Ake JA, Vasan S, Pantaleo G, Frank I, Baden LR, Goepfert PA, Keefer M, Chirenje M, Hosseinipour MC, Mngadi K, Laher F, Garrett N, Bekker LG, De Rosa S, Andersen-Nissen E, Kublin JG, Lu S, Gilbert PB, Gray GE, Corey L, McElrath MJ, Tomaras GD.   +38 more
europepmc   +1 more source

Large Language Models for Clinical Trial Protocol Assessments

Clinical Pharmacology &Therapeutics, Volume 119, Issue 2, Page 393-402, February 2026.
The purpose was to evaluate the utility of large language models (LLMs) for reviewing the statistical analysis plan (SAP) and pharmacokinetics–pharmacodynamics (PK–PD) components of clinical trial protocols. Clinical trial protocols and SAPs were obtained from clinicaltrials.gov for a testbed of 15 small‐molecule drugs, biologics, and global antibiotic
Euibeom Shin, Amruta Gajanan Bhat, Murali Ramanathan   +2 more
wiley   +1 more source

Non-HIV Vaccine-Induced Immune Responses as Potential Baseline Immunogenicity Predictors of ALVAC-HIV and AIDSVAX B/E-Induced Immune Responses. [PDF]

Viruses
Huang Y, Alam S, Andersen-Nissen E, Carpp LN, Dintwe OB, Flach BS, Grunenberg N, Laher F, De Rosa SC, Ferrari G, Innes C, Bekker LG, Kublin JG, McElrath MJ, Tomaras GD, Gray GE, Gilbert PB.   +16 more
europepmc   +1 more source

Metabolic reprogramming of efferocytosis in the tumour microenvironment: From apoptotic‐cell clearance to therapeutic targeting

Clinical and Translational Medicine, Volume 16, Issue 2, February 2026.
This review systematically deconstructs the pathological efferocytic—metabolic axis in tumours, framing it as a three‐stage, self‐reinforcing cycle: from metabolite‐driven macrophage recruitment, through hijacked surface recognition, to post‐phagocytic metabolic reprogramming that locks in immunosuppression.
Qianlu Yang, Jie Yan, Qianxi Yang
wiley   +1 more source

Vaccine Incentives Harm Intrinsic Motivation: Evidence From a Priming Experiment

Health Economics, Volume 35, Issue 2, Page 312-331, February 2026.
ABSTRACT Monetary incentives for vaccination may undermine intrinsic motivation, but evidence on this effect remains scarce. We conducted an experiment among 513 vaccine‐hesitant adults to test whether priming individuals with a monetary incentive reduces their willingness to vaccinate against COVID‐19.
Johnny Huynh, Corey Jacinto, James Huynh
wiley   +1 more source

An Empty Scoping Review on the Financing of Necrotizing Periodontal Disease Prevention and Control in Africa: Implications for Global Oral Health Research, Policy, and Practice

Health Science Reports, Volume 9, Issue 2, February 2026.
ABSTRACT Background and Aims Necrotizing periodontal diseases (NPDs) represent a significant yet neglected burden in sub‐Saharan Africa, often exacerbated by poverty, malnutrition, HIV, and limited access to oral healthcare. Despite their public health relevance, financing mechanisms supporting their prevention and control in African settings are ...
Kafayat Aminu, Yovanthi Anurangi Jayasinghe, Oluwatobi Emmanuel Adegbile, Adetayo Olorunlana, Rita Amarachi Nwebo, Precious Chika Nnannah, Afeez Abolarinwa Salami, Akinyele Olumuyiwa Adisa, Ugochukwu Anthony Eze, Kehinde Kazeem Kanmodi   +9 more
wiley   +1 more source

Eliciting CD4-mimicking broadly neutralizing antibodies: new avenues towards the rational design of an HIV vaccine. [PDF]

Signal Transduct Target Ther
Muecksch F, Fackler OT.
europepmc   +1 more source

Recovery Rate of Under‐Five Children From Severe Acute Malnutrition and Its Predictors in Ethiopia: A Systematic Review and Meta‐Analysis

Health Science Reports, Volume 9, Issue 2, February 2026.
ABSTRACT Background Previous reviews on severe acute malnutrition recovery in Ethiopia were limited by outdated data and narrow scope. This study used recent and regionally diverse data, including from conflict‐affected areas, to inform current nutrition efforts.
Temesgen Gebeyehu Wondmeneh, Oumer Abdulkadir Ebrahim   +1 more
wiley   +1 more source

Mosquito‐Borne Viruses of Clinical Significance

Health Science Reports, Volume 9, Issue 2, February 2026.
ABSTRACT Background Mosquito‐borne viruses represent a significant public health concern globally, with rising incidence rates leading to increased morbidity and mortality. This review aims to synthesize current knowledge regarding mosquito‐borne viruses, focusing on their geographic distribution, clinical impact, diagnostic challenges, treatment ...
Donath Damian
wiley   +1 more source