Results 261 to 270 of about 246,153 (308)
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Evaluation Review, 1993
The development of an effective preventive vaccine against the human immunodeficiency virus (HIV) is an urgent national and international priority. However, a number of formidable obstacles, encompassing biomedical, logistic, economic, social, and psychosocial concerns, must be overcome to ensure the proper distribution and use of an HIV vaccine once ...
Steven D. Pinkerton, Paul R. Abramson
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The development of an effective preventive vaccine against the human immunodeficiency virus (HIV) is an urgent national and international priority. However, a number of formidable obstacles, encompassing biomedical, logistic, economic, social, and psychosocial concerns, must be overcome to ensure the proper distribution and use of an HIV vaccine once ...
Steven D. Pinkerton, Paul R. Abramson
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Vaccine, 2002
Traditional methods of vaccine development have not produced effective vaccines for several prevalent infectious diseases, including AIDS, malaria and tuberculosis. These difficult diseases call attention to the importance of new approaches that profit from modern technologies.
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Traditional methods of vaccine development have not produced effective vaccines for several prevalent infectious diseases, including AIDS, malaria and tuberculosis. These difficult diseases call attention to the importance of new approaches that profit from modern technologies.
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Vaccines under study: non-HIV vaccines
Dermatologic Therapy, 2009The development of effective vaccines has been an amazing public health achievement and has resulted in countless lives being saved. Dermatologic therapy has recently been greatly advanced by the licensure of an effective human papillomavirus vaccine and herpes zoster vaccine.
Kelly, Conner +4 more
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Vaccines and Vaccine Strategies Against HIV
Current Drug Targets, 2004The HIV/AIDS pandemic is a global emergency and a preventive HIV vaccine is urgently needed. HIV has, however, proved a difficult pathogen to vaccinate against. This is largely because HIV has a very high mutation rate and can escape immune responses, it has a latent stage where it can rest silently integrated into host DNA, and neutralising antibodies
Ivan, Stratov +3 more
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Current Opinion in HIV and AIDS, 2016
Advances in the understanding of the structural biology of HIV-1 proteins, and in the vulnerabilities of HIV-1 at various points in the infectious process have led to innovative approaches for vaccine constructs for clinical trials. Lessons from the successful Retrovirology study 144 (RV144) phase III Thai trial have revealed the need for novel and ...
Mangala, Rao, Carl R, Alving
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Advances in the understanding of the structural biology of HIV-1 proteins, and in the vulnerabilities of HIV-1 at various points in the infectious process have led to innovative approaches for vaccine constructs for clinical trials. Lessons from the successful Retrovirology study 144 (RV144) phase III Thai trial have revealed the need for novel and ...
Mangala, Rao, Carl R, Alving
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American Journal of Epidemiology, 1995
It is unlikely that human immunodeficiency virus (HIV) vaccines will create impenetrable barriers to infection. When the barriers to infection are broken, however, vaccine effects on the progression of infection to disease and on the contagiousness of infection could be considerable. The usual outcomes of vaccine trials are either infection or disease.
J S, Koopman, R J, Little
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It is unlikely that human immunodeficiency virus (HIV) vaccines will create impenetrable barriers to infection. When the barriers to infection are broken, however, vaccine effects on the progression of infection to disease and on the contagiousness of infection could be considerable. The usual outcomes of vaccine trials are either infection or disease.
J S, Koopman, R J, Little
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Dermatologic Therapy, 2009
Human immunodeficiency virus (HIV) infection is a worldwide epidemic, with over 42 million people currently infected. Since the discovery of HIV as the causative agent of the acquired immune deficiency syndrome (AIDS), many potential vaccines have been created.
Parisa, Ravanfar +3 more
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Human immunodeficiency virus (HIV) infection is a worldwide epidemic, with over 42 million people currently infected. Since the discovery of HIV as the causative agent of the acquired immune deficiency syndrome (AIDS), many potential vaccines have been created.
Parisa, Ravanfar +3 more
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Topics in HIV medicine : a publication of the International AIDS Society, USA, 2009
Updates on the Thai clinical vaccine trial, the discovery of additional neutralizing antibodies, and several new, nonhuman primate vaccine studies were presented at the 17th Conference on Retroviruses and Opportunistic Infections this year. Interestingly, the vaccine effect observed in the Thai trial diminished with time and was most effective in ...
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Updates on the Thai clinical vaccine trial, the discovery of additional neutralizing antibodies, and several new, nonhuman primate vaccine studies were presented at the 17th Conference on Retroviruses and Opportunistic Infections this year. Interestingly, the vaccine effect observed in the Thai trial diminished with time and was most effective in ...
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Journal of Infection, 2002
In this review, we address recent advances in the understanding of the pathogenesis of human immunodeficiency type 1 virus infection, which have provided the rationale for present trials of therapeutic vaccines. We shall relate this work to lessons of the past few years both in the use of highly active antiretroviral therapy to attempt eradication of ...
S, Kinloch-de Loes, B, Autran
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In this review, we address recent advances in the understanding of the pathogenesis of human immunodeficiency type 1 virus infection, which have provided the rationale for present trials of therapeutic vaccines. We shall relate this work to lessons of the past few years both in the use of highly active antiretroviral therapy to attempt eradication of ...
S, Kinloch-de Loes, B, Autran
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Clinical Pharmacology & Therapeutics, 2007
Development of an HIV/AIDS vaccine has been slow because classical approaches to vaccine development have not yielded a vaccine. Encouragingly, new approaches using recombinant viral vectors, DNA vaccines, and combinations of different vectors in heterologous prime/boost regimens are yielding vaccines capable of controlling virulent immunodeficiency ...
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Development of an HIV/AIDS vaccine has been slow because classical approaches to vaccine development have not yielded a vaccine. Encouragingly, new approaches using recombinant viral vectors, DNA vaccines, and combinations of different vectors in heterologous prime/boost regimens are yielding vaccines capable of controlling virulent immunodeficiency ...
openaire +2 more sources