Results 21 to 30 of about 246,153 (308)

Protocol for a randomized clinical trial exploring the effect of antimicrobial agents on the penile microbiota, immunology and HIV susceptibility of Ugandan men

Trials, 2019
Background The foreskin is the main site of HIV acquisition in a heterosexual uncircumcised man, but many men in endemic countries are reluctant to undergo penile circumcision (PC).
Ronald M. Galiwango, Bernard Bagaya, Juliet Mpendo, Vineet Joag, Brenda Okech, Annet Nanvubya, Ali Ssetaala, Moses Muwanga, Rupert Kaul   +8 more
doaj   +1 more source

Declining HIV-1 Prevalence and Incidence among Police Officers - A potential Cohort for HIV Vaccine Trials, in Dar es Salaam, Tanzania. [PDF]

, 2013
A safe effective and affordable HIV vaccine is the most cost effective way to prevent HIV infection worldwide. Current studies of HIV prevalence and incidence are needed to determine potentially suitable cohorts for vaccine studies.
Bo Hejdeman, EF Lyamuya, Eric Aris, Eric Sandstrom, J Esparza, J Esparza, M Bakari, M Bakari, Mohamed Janabi, Muhammad Bakari, Patricia J Munseri, PJ Munseri, S Aboud, S Rerks-Ngarm, Said Aboud, Tanzania Commission for AIDS (TACAIDS) ZACZ, National Bureau of Statistics (NBS), Office of Chief Government Statistician (OCGS), and Macro International Inc, UNAIDS, UNAIDS   +17 more
core   +1 more source

Immunogens and Antigen Processing: Report from a Global HIV Vaccine Enterprise Working Group [PDF]

, 2010
The Global HIV Vaccine Enterprise convened a meeting of a Working Group in July 2009 to discuss recent progress in rational design of the components of an HIV vaccine, such as inserts, vectors and adjuvants,and in understanding antigen processing and ...
John Mascola, Ralph Steinman, Richter C. King, the Working Group convened by the Global HIV Vaccine Enterprise   +3 more
core   +3 more sources

Mobility for maternal health among women in hard-to-reach fishing communities on Lake Victoria, Uganda; a community-based cross-sectional survey

BMC Health Services Research, 2021
Background Maternal mortality is still a challenge in Uganda, at 336 deaths per 100,000 live births, especially in rural hard to reach communities. Distance to a health facility influences maternal deaths. We explored women’s mobility for maternal health,
Ali Ssetaala, Julius Ssempiira, Gertrude Nanyonjo, Brenda Okech, Kundai Chinyenze, Bernard Bagaya, Matt A Price, Noah Kiwanuka, Olivier Degomme   +8 more
doaj   +1 more source

Deconvolving mutational patterns of poliovirus outbreaks reveals its intrinsic fitness landscape. [PDF]

, 2020
Vaccination has essentially eradicated poliovirus. Yet, its mutation rate is higher than that of viruses like HIV, for which no effective vaccine exists.
Barton, John P, Chakraborty, Arup K, McKay, Matthew R, Quadeer, Ahmed A   +3 more
core   +3 more sources

Health disparities in chronic liver disease

Hepatology, EarlyView., 2022
Abstract The syndemic of hazardous alcohol consumption, opioid use, and obesity has led to important changes in liver disease epidemiology that have exacerbated health disparities. Health disparities occur when plausibly avoidable health differences are experienced by socially disadvantaged populations.
Ani Kardashian, Marina Serper, Norah Terrault, Lauren D. Nephew   +3 more
wiley   +1 more source

Host Genetics and Viral Diversity: Report from a Global HIV Vaccine Enterprise Working Group [PDF]

, 2010
The Global HIV Vaccine Enterprise convened a workshop in September 2009 to discuss human and viral genetic variation and its impact on future directions for HIV vaccine research and development.
Andrew McMichael, Francine McCutchan, the Working Group convened by the Global HIV Vaccine Enterprise   +2 more
core   +3 more sources

Identification of novel neutralizing determinants for protection against HCV

Hepatology, EarlyView., 2022
Identification of novel neutralizing determinants for protection against hepatitis C virus. Abstract Background and Aims HCV evasion of neutralizing antibodies (nAb) results in viral persistence and poses challenges to the development of an urgently needed vaccine.
Garazi P. Alzua, Anne F. Pihl, Anna Offersgaard, Rodrigo Velázquez‐Moctezuma, Carlos R. Duarte Hernandez, Elias H. Augestad, Ulrik Fahnøe, Christian K. Mathiesen, Henrik Krarup, Mansun Law, Jannick Prentoe, Jens Bukh, Judith M. Gottwein   +12 more
wiley   +1 more source

Vaccination against HIV

Immunobiology, 1992
The spread of AIDS progresses unrelentingly despite all efforts of public education and the only real hope of epidemiological control lies in the development of an effective vaccine. The very nature of the AIDS virus (HIV) and the manner with which it interacts with the host makes development of a practical vaccine very difficult.
S, Norley, R, Kurth
openaire   +2 more sources

Attracting, equipping and retaining young medical doctors in HIV vaccine science in South Africa

Southern African Journal of HIV Medicine, 2015
Background: HIV remains a significant health problem in South Africa (SA). The development of a preventive vaccine offers promise as a means of addressing the epidemic, yet development of the human resource capacity to facilitate such research in SA is ...
Danna Flood, Melissa Wallace, Kimberly Bloch, James Kublin, Linda-Gail Bekker   +4 more
doaj   +1 more source