Results 31 to 40 of about 246,153 (308)

A combined adjuvant approach primes robust germinal center responses and humoral immunity in non-human primates

Nature Communications, 2023
Adjuvants and antigen delivery kinetics can profoundly influence B cell responses and should be critically considered in rational vaccine design, particularly for difficult neutralizing antibody targets such as human immunodeficiency virus (HIV). Antigen
Ivy Phung, Kristen A. Rodrigues, Ester Marina-Zárate, Laura Maiorino, Bapi Pahar, Wen-Hsin Lee, Mariane Melo, Amitinder Kaur, Carolina Allers, Marissa Fahlberg, Brooke F. Grasperge, Jason P. Dufour, Faith Schiro, Pyone P. Aye, Paul G. Lopez, Jonathan L. Torres, Gabriel Ozorowski, Saman Eskandarzadeh, Michael Kubitz, Erik Georgeson, Bettina Groschel, Rebecca Nedellec, Michael Bick, Katarzyna Kaczmarek Michaels, Hongmei Gao, Xiaoying Shen, Diane G. Carnathan, Guido Silvestri, David C. Montefiori, Andrew B. Ward, Lars Hangartner, Ronald S. Veazey, Dennis R. Burton, William R. Schief, Darrell J. Irvine, Shane Crotty   +35 more
doaj   +1 more source

Schistosoma mansoni infection and socio-behavioural predictors of HIV risk: a cross-sectional study in women from Uganda

BMC Infectious Diseases, 2018
Background Schistosoma mansoni infection has been associated with increased risk of HIV transmission in African women. This association might be causal or mediated through shared socio-behavioural factors and associated co-infections.
Sergey Yegorov, Ronald M. Galiwango, Sara V. Good, Juliet Mpendo, Egbert Tannich, Andrea K. Boggild, Noah Kiwanuka, Bernard S. Bagaya, Rupert Kaul   +8 more
doaj   +1 more source

Community stakeholder engagement during a vaccine demonstration project in Nigeria: lessons on implementation of the good participatory practice guidelines

The Pan African Medical Journal, 2019
INTRODUCTION: to report on the successes and challenges with implementing the good participatory practice guidelines for the Nigerian Canadian Collaboration on AIDS Vaccine (NICCAV) project.Methods: an open and close ended questionnaire was administered ...
Morenike Oluwatoyin Folayan, Florita Durueke, Wika Gofwen, Godwin Godo-Odemijie, Chuks Okonkwo, Bali Nanmak, Sophia Osawe, Evaezi Okporoko, Alash’le Abimiku   +8 more
doaj   +1 more source

Phage display selection of HIV specific conserved mimotopes with IgG from long-term non-progressors [PDF]

, 2005
Poster presentation Background The aim of this study is to identify conserved epitopes of HIV-1 neutralizing antibodies in polyclonal plasma from LTNP to finally derive vaccine candidates.
Antoni, Sascha, Dietrich, Ursula, Dittmar, Matthias, Humber, Michael, Rodes, Berta, Schreiber, Andreas, Soriano, Vicente   +6 more
core   +1 more source

A global approach to HIV-1 vaccine development [PDF]

, 2014
Summary A global human immunodeficiency virus-1 (HIV-1) vaccine will have to elicit immune responses capable of providing protection against a tremendous diversity of HIV-1 variants.
Barouch, Dan H, Stephenson, Kathryn E
core   +1 more source

Vaginal practices among women at risk for HIV acquisition in Soweto, South Africa

Southern African Journal of HIV Medicine, 2019
Background: Vaginal practices (VP) may adversely affect normal vaginal flora and mucosal integrity, and increase acquisition risk of HIV and other genital tract infections.
Erica Lazarus, Kennedy Otwombe, Janan Dietrich, Michele P. Andrasik, Cecilia A. Morgan, James G. Kublin, Glenda E. Gray, Abby J. Isaacs, Fatima Laher   +8 more
doaj   +1 more source

HIV Immunotherapeutic Vaccines

Antiviral Chemistry and Chemotherapy, 2000
New combinations of antiretrovirals have improved the quality of life and length of survival of patients with HIV infection and AIDS, but they have significant disadvantages. These include considerable toxicity, the development of drug resistance and expense. Successful immunotherapeutic vaccination against HIV would overcome these problems.
openaire   +2 more sources

A Compensatory Liability Regime to Promote the Exchange of Microbial Genetic Resources for Research and Benefit Sharing [PDF]

, 2011
Female rhesus macaques were immunized with HIV virus-like particles (HIV-VLPs) or HIV DNA administered as sequential combinations of mucosal (intranasal) and systemic (intramuscular) routes, according to homologous or heterologous prime-boost schedules ...
Andersen, Hanne, Buonaguro, Franco M., Buonaguro, Luigi, Hinkula, Jorma, Lewis, Mark, Pal, Ranajit, Schroeder, Ulf, Tagliamonte, Maria, Torneselloa, Maria Lina, Visciano, Maria Luisa, Wahren, Britta   +10 more
core   +2 more sources

Monoclonal Antibodies against Plasmodium falciparum Circumsporozoite Protein

Antibodies, 2017
Malaria is a mosquito-borne infectious disease caused by the parasite Plasmodium spp. Malaria continues to have a devastating impact on human health. Sporozoites are the infective forms of the parasite inside mosquito salivary glands.
Min Zhang, Rajakumar Mandraju, Urvashi Rai, Takayuki Shiratsuchi, Moriya Tsuji   +4 more
doaj   +1 more source

Prevalence and correlates of HIV infection among adolescents and young people living in fishing populations along Lake Victoria Fishing Communities in Uganda

The Pan African Medical Journal, 2020
INTRODUCTION: Fishing communities in Uganda are key populations for HIV, with persistently higher prevalence and incidence than the general population.
Gertrude Nanyonjo, Gershim Asiki, Ali Ssetaala, Teddy Nakaweesa, Mathias Wambuzi, Annet Nanvubya, Juliet Mpendo, Brenda Okech, Paul Kato Kitandwe, Leslie Nielsen, Annet Nalutaaya, Sabrina Welsh, Bernard Ssentalo Bagaya, Kundai Chinyenze, Pat Fast, Matt Price, Noah Kiwanuka   +16 more
doaj   +1 more source