Results 261 to 270 of about 223,968 (292)
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Genetical Factors—other than HLA-B27—in “HLA-B27-associated diseases”
Scandinavian Journal of Rheumatology, 1990All studies among acute anterior uveitis (AAU) and ankylosing spondylitis (AS) agree on the importance of and high association with HLA-B27. However, the majority (greater than 95%) of the HLA-B27+ population will never develop such disease. There are two--generally accepted--important factors increasing the relative risk for developing AAU or AS ...
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HLA-B27-Associated Cardiac Disease
Annals of Internal Medicine, 1997To review the available information about cardiac disease in relation to the immunogenetic marker HLA-B27 and the inflammatory disorders associated with it (seronegative spondyloarthropathies).English-language clinical studies, case reports, and reviews published in 1995 or earlier were identified from a search of the MEDLINE database.
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Acute Anterior Uveitis and HLA-B27
Survey of Ophthalmology, 1991Acute anterior uveitis is a common ocular disease characterized by inflammation of the iris and ciliary body. In the majority of patients presenting with an acute attack of anterior uveitis, the only clues to the pathogenesis of this disease are its close association with the genetic marker HLA-B27 and the likely triggering role of a variety of gram ...
John H, Chang +2 more
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HLA-B27-assoziierte Arthritiden – Spondylarthropathien
2004Wie beim Erwachsenen gibt es auch bei Kindern Arthritiden, die zum einen mit HLA B27-assoziiert sind und zum anderen ein hohes Risiko fur einen Achsenskelettbefall, an Iliosakralgelenken und Wirbelsaule aufweisen. Zu dieser Erkrankungsgruppe zahlen die reaktive Arthritis und das Reiter-Syndrom, die juvenile Spondylitis ankylosans, Psoriasisarthritis ...
G. Horneff, V. Wahn
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The Pathogenesis of HLA-B27 Arthritis: Role of HLA-B27 in Bacterial Defense
The American Journal of the Medical Sciences, 1998The way in which a host accommodates invasive facultative intracellular bacteria must be the key to the development of reactive arthritis. Investigators have analyzed the bacterial events at several levels: invasion into host cells, intracellular survival, translocation from the sites of infection to the joints, residence in the joints, and evasion of ...
M, Ikeda, D T, Yu
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Monoclonal Antibodies to HLA-B27
Rheumatology, 1983Because HLA-B27 is such an important genetic marker for susceptibility to spondyloarthropathies and other related diseases, study of this alloantigen was undertaken using murine monoclonal antibodies. The first monoclonal anti-B27 antibody, B27M1, is an IgG2a lymphocytotoxic antibody that reacts with all B27 antigens and cross-reacts to a lesser degree
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Revue du Rhumatisme, 2001
Resume HLA-B27 est un marqueur serologique correspondant a 25 alleles qui codent pour 23 proteines differentes : HLA-B*2701 a B*2723. Ces alleles sont aussi nommes sous-types d’HLA-B27 et seraient issus du sous-type le plus repandu B*2705. Les differences entre ces sous-types resident principalement dans les exons 2 et 3 codant respectivement pour ...
Edward J Ball, Muhammad Asim Khan
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Resume HLA-B27 est un marqueur serologique correspondant a 25 alleles qui codent pour 23 proteines differentes : HLA-B*2701 a B*2723. Ces alleles sont aussi nommes sous-types d’HLA-B27 et seraient issus du sous-type le plus repandu B*2705. Les differences entre ces sous-types resident principalement dans les exons 2 et 3 codant respectivement pour ...
Edward J Ball, Muhammad Asim Khan
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1984
As in the previous Workshops, HLA-B27 appears to be one of the best defined antigens. Four sera are very good or excellent (Table 1) as, indicated by their quality scores based on the formula of Mickey and Terasaki. The few extra reactions of the above-mentioned sera are cross-reactions, mostly with B7.
B. S. Breur, P. Ivanyi
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As in the previous Workshops, HLA-B27 appears to be one of the best defined antigens. Four sera are very good or excellent (Table 1) as, indicated by their quality scores based on the formula of Mickey and Terasaki. The few extra reactions of the above-mentioned sera are cross-reactions, mostly with B7.
B. S. Breur, P. Ivanyi
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1990
In 1973 two studies reported almost simultaneously the highly significant association between HLA-B27 (B27) and ankylosing spondylitis (AS) (Schlosstein 1973; Brewerton 1973a). In the former study 88% of the patients (all Caucasion) were B27 positive compared to only 8% of the controls. Across the Atlantic the results were similar.
H. S. Luthra +3 more
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In 1973 two studies reported almost simultaneously the highly significant association between HLA-B27 (B27) and ankylosing spondylitis (AS) (Schlosstein 1973; Brewerton 1973a). In the former study 88% of the patients (all Caucasion) were B27 positive compared to only 8% of the controls. Across the Atlantic the results were similar.
H. S. Luthra +3 more
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2013
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