Background The human leukocyte antigen (HLA)-B27 gene is highly associated with ankylosing spondylitis (AS). However, not everyone who carries the HLA-B27 antigen develops AS, indicating that factors beyond the HLA-B27 gene contribute to the disease’s ...
Kuang-Hui Yu +5 more
doaj +1 more source
The rapid detection of human HLA-B*27 gene based on BASIC isothermal detection
Ankylosing spondylitis (AS) is a chronic, inflammatory arthritis of the spine and peripheral joints which is known to have a strong association with the human leukocyte antigen B27 (HLA-B27).
Ying Chen +9 more
doaj +1 more source
聚合酶链反应-直接测序法在强直性脊柱炎患者HLA-B27检测中的应用
目的探讨聚合酶链反应-直接测序法(polymerase chain reaction sequence-based typing,PCR-SBT)检测人类白细胞抗原B27(human leukocyte antigen B27,HLA-B27)在强直性脊柱炎(ankylosing spondylitis,AS)临床诊断中的价值。方法应用PCR-SBT法和临床常用的IMS-ELISA法对120例疑似AS患者外周血进行HLA-B27检测。以SPSS17 ...
王平均 +4 more
doaj
HLA class-I-transgenic mice as model system to study MHC-restricted antigen recognition in man [PDF]
McMichael, A. +15 more
core +1 more source
Impact of sex and HLA-B27 positivity on clinical characteristics and patient-reported outcomes in a cohort of Egyptian axial spondyloarthritis patients. [PDF]
Soliman E +3 more
europepmc +1 more source
HLA-J, A SECOND INACTIVATED CLASS I HLA GENE RELATED TO HLA-G AND HLA-A [PDF]
Zemmour, Jaqueline +5 more
core +1 more source
Editor’s Pick: Why Do Diseases Start One Sided? Clues from Hla-b27 Acute Anterior Uveitis
Uveitis is an inflammatory disease with significant disease burden, as it causes ≤10% of legal blindness in the USA. Patients are usually affected in their prime working years.
Margo S. Clarke
core
Computational identification and experimental validation of shared diagnostic biomarkers and gene signatures across HLA-B27-associated immune-mediated diseases. [PDF]
Zhu X +12 more
europepmc +1 more source
Anterior endogenous uveitis and HLA-B27 antigen
G. Zhaboedov, N. Ivanova, A. Kopaenko
openaire +1 more source
Recent updates in human leukocyte antigen B27-associated uveitis. [PDF]
Narain S +4 more
europepmc +1 more source

