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HLA-B27 [PDF]

open access: yesAnnual Review of Immunology, 2015
Possession of the human leukocyte antigen (HLA) class I molecule B27 is strongly associated with ankylosing spondylitis (AS), but the pathogenic role of HLA-B27 is unknown.
Paul Bowness
exaly   +2 more sources

HLA-B27 and Antigen Presentation: At the Crossroads Between Immune Defense and Autoimmunity

open access: yesMolecular Immunology, 2014
The HLA-B27 is historically studied as a susceptibility factor in spondyloarthropathies and, primarily, in ankylosing spondylitis (AS). Over the recent years however, it has been rediscovered as protective factor against some severe viral infections ...
Maria Teresa Fiorillo   +2 more
exaly   +2 more sources
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Biochemical analysis of variant HLA-B27 antigens

Human Immunology, 1983
Biochemical analysis of HLA-B27 antigens from individuals that are HLA-ABC identical by serology but distinct in CML typing establishes that two types of HLA-B27 can be defined biochemically. The division of HLA-B27 into a W type and a K type by CML typing correlates perfectly with the biochemical data. HLA-B27 K type possesses a more basic isoelectric
H H, Mölders   +3 more
openaire   +2 more sources

Association of HLA-B27 Antigen with Retroperitoneal Fibrosis

Journal of Urology, 1978
This is the second known case of retroperitoneal fibrosis in a middle-aged black man whose tissue type was HLA-B27 positive. The HLA-B27 antigen is present in only 4 per cent of black American male subjects and may be important in the diagnosis and management of patients with primary retroperitoneal fibrosis.
M K, Willscher   +2 more
openaire   +2 more sources

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