Results 221 to 230 of about 144,091 (315)

AlphaFold and Docking Approaches for Antibody–Antigen and Other Targets: Insights From CAPRI Rounds 47–55

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT Accurate modeling of the structures of protein–protein complexes and other biomolecular interactions represents a longstanding and important challenge for computational biology. The Critical Assessment of PRedicted Interactions (CAPRI) experiment has served for over two decades as a key means to assess and compare current approaches and ...
Ragul Gowthaman, Minjae Park, Rui Yin, Johnathan D. Guest, Brian G. Pierce   +4 more
wiley   +1 more source

Cellular Immune Response and T Cell Epitope Mapping of <i>Plasmodium falciparum</i> Chimeric Vaccine Candidate GMZ2.6c and Its Components (MSP-3, GLURP and Pfs48/45) in Individuals Naturally Exposed to Malaria in Brazilian Amazon. [PDF]

Vaccines (Basel)
Baptista BO, Soares IF, de Souza HADS, Barros JP, Riccio EKP, Martorano RM, Rodrigues-da-Silva RN, Amoah LE, Singh SK, Theisen M, Lima-Junior JDC, Totino PRR, Daniel-Ribeiro CT, Pratt-Riccio LR.   +13 more
europepmc   +1 more source

Biomolecular Interaction Prediction in the Pre‐ and Post‐AlphaFold Era: The 8th CAPRI Evaluation

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT We report on the 8th CAPRI Evaluation period, capturing the assessment of CAPRI Rounds 47 to 55 (excluding the CASP and COVID‐related Rounds), which have witnessed the transition to AI‐driven prediction tools such as AlphaFold and related alternatives. The prediction Rounds in this evaluation are characterized by a high level of difficulty due
Marc F. Lensink, Nessim Raouraoua, Guillaume Brysbaert, Sameer Velankar, Shoshana J. Wodak, Alexandre M. J. J. Bonvin   +5 more
wiley   +1 more source

Why Is MS a More Frequent Complication of EBV Infection in Females? [PDF]

Immunol Rev
Dunn SE, Alvarez-Sanchez N, Steinman L.
europepmc   +1 more source

Harnessing Natural Compounds in Psoriasis: Targeting Cellular Pathways for Effective Therapy

Phytotherapy Research, EarlyView.
Natural compounds act on key cellular pathways in psoriasis by suppressing keratinocyte hyperproliferation, modulating Th17/IL‐17‐mediated immune responses, and reducing oxidative stress. These multi‐target effects highlight their potential as safer adjunctive therapies alongside conventional treatments.
Hye Jin Lee, Yu Jin So, Il‐Joo Jo, Ji Yong Jang, Tae Han Yook, Jun Ho Lee, Sung Wook Kim, Kangwook Lee, Soo Jung Park, Gabsik Yang   +9 more
wiley   +1 more source

Mechanisms of paraneoplastic neurological syndromes. [PDF]

Curr Opin Neurol
Kunchok A, Vogrig A, Graus F.
europepmc   +1 more source

Mesenchymal stromal cell therapy for rheumatoid arthritis: Long‐term efficacy, safety, and mechanistic insights

Rheumatology &Autoimmunity, EarlyView.
Graphical abstract summarizing the multifactorial pathogenesis of rheumatoid arthritis (RA) and the therapeutic potential of mesenchymal stromal cell (MSC) therapy. MSCs provide promising benefits through their immunomodulatory properties, low immunogenicity, ability to promote tissue repair, and multi‐lineage differentiation, presenting a potential ...
Yingjia Chen, Ruiyu Gao, Xing Guo, Genhong Yao, Xiaojun Tang, Yile E. Liu, Lingyun Sun   +6 more
wiley   +1 more source

Nomenclature for Factors of the HLA System, 2026. [PDF]

HLA
Marsh SGE, Osoegawa K, Bodmer WF, Bontrop RE, Carrington MN, Erlich HA, Heidt S, Holdsworth R, Mayr WR, Maiers M, Parham P, Petersdorf EW, Robinson J, Trowsdale J, Fernández-Viña M.   +14 more
europepmc   +1 more source

TEpiNom: A computational framework integrating population data to prioritize Plasmodium falciparum T cell epitopes. [PDF]

Vaccine
Laurenson AJ, Pierce BG, Takala-Harrison S, Laurens MB.   +3 more
europepmc   +1 more source

Responsive nitric oxide‐releasing antibacterial materials for biofilm‐associated infections: Mechanisms, design strategies, and applications

Responsive Materials, EarlyView.
This review summarizes the recent progress in responsive NO‐releasing materials and their applications in biofilm‐associated infectious diseases. The design principles and response mechanisms are given to provide inspiration toward the future development of multi‐responsive NO‐releasing materials.
Wenyue Sun, Meiqi Li, Di Nan, Jiaqi Zhao, Yu Chen, Yao Gao, Shichen Zhang, Kirsten L. Van Landuyt, Manlin Qi   +8 more
wiley   +1 more source