Macrophage Phenotype Alterations in Treated Periodontitis Patients Suggest a Pro‐Inflammatory Bias
Monocyte‐derived macrophages from successfully treated stage III periodontitis patients show a persistent skewing toward an M1‐like pro‐inflammatory phenotype across polarization conditions, suggesting that immune dysregulation may persist despite clinical periodontal stability.
Mariane Cristina Sloniak +5 more
wiley +1 more source
HLA-DR genotypes in patients with primary Sjögren's syndrome in Taiwan. [PDF]
Yen CY +6 more
europepmc +1 more source
Extracorporeal photopheresis (ECP) induces apoptosis in circulating immune cells, but its kinetics vary slightly depending on the cell type. We compared the progression of apoptosis in PBMCs versus highly purified T cells exposed to 8‐methoxypsoralen and ultraviolet A.
Carlos Agustin Villegas‐Valverde +6 more
wiley +1 more source
HLA-DR⁺ Tumor Cells Show an Association with a Distinct Immune Microenvironment and CD8⁺ T-Cell Exhaustion in HBV-Associated Hepatocellular Carcinoma. [PDF]
Chang JQ +17 more
europepmc +1 more source
Abstract Orthodontic therapy applies forces to teeth, causing an inflammatory reaction in the periodontal ligament. This is repaired by remodeling of the periodontium, allowing tooth displacement. Although orthodontic therapy is mostly initiated during childhood and adolescence, the number of adults seeking this treatment is increasing as our society's
Ludovica Parisi +4 more
wiley +1 more source
The CD38+HLA-DR+ T cells with activation and exhaustion characteristics as predictors of severity and mortality in COVID-19 patients. [PDF]
Long Q +15 more
europepmc +1 more source
Antibiotic‐mediated immune modulation in periodontitis
Abstract Periodontitis is a chronic inflammatory disease affecting the supporting structures of the teeth. Although initiated by dysbiotic microbial communities, its progression is largely driven by the host's uncontrolled inflammatory response. While antibiotics have conventionally been employed in periodontitis therapy for their antimicrobial ...
Lina J. Suárez +6 more
wiley +1 more source
CD8<sup>+</sup>HLA-DR<sup>+</sup>CD27<sup>+</sup> T cells define a population of naturally occurring regulatory precursors in humans. [PDF]
Guo H +12 more
europepmc +1 more source
ABSTRACT Microbial mats and microbialites are common in modern and ancient saline lacustrine environments and are highly responsive to biological and environmental factors. As such, they represent important sources of high‐resolution environmental data across a wide range of geological time. Nonetheless, interpretation of fossil mats is non‐trivial due
Connor Doyle +6 more
wiley +1 more source
Proinflammatory and cytotoxic CD38<sup>+</sup>HLA-DR<sup>+</sup> effector memory CD8<sup>+</sup> T cells are peripherally expanded in human cardiac allograft vasculopathy. [PDF]
Tada Y +13 more
europepmc +1 more source

