Results 1 to 10 of about 108,857 (212)

Prediction of immunogenicity of Rh antigens using in silico analysis of binding to human leukocyte antigen peptide, Basic/Translational Research. [PDF]

open access: yesPLoS ONE
The association between human leukocyte antigen (HLA) types and blood group alloimmunization remains unclear. Previous studies have predominantly focused on predicting immunization events in cancer immunotherapy, but not blood group antigens.
Hee-Jeong Youk   +4 more
doaj   +2 more sources

Human leukocyte antigen variation among Iranian renal transplant recipients [PDF]

open access: yesJournal of Nephropathology, 2012
Background: HLA typing analysis is important in renal transplant patients. Objectives: We made a plan to determine the most frequent HLA antigens in Iranian kidney transplant patients.
Behzad Einollahi   +2 more
doaj   +1 more source

Modular adjuvant-free pan-HLA-DR-immunotargeting subunit vaccine against SARS-CoV-2 elicits broad sarbecovirus-neutralizing antibody responses

open access: yesCell Reports, 2023
Summary: Subunit vaccines typically require co-administration with an adjuvant to elicit protective immunity, adding development hurdles that can impede rapid pandemic responses.
Audrey Kassardjian   +11 more
doaj   +1 more source

Comprehensive Analysis of CD4+ T Cell Response Cross-Reactive to SARS-CoV-2 Antigens at the Single Allele Level of HLA Class II

open access: yesFrontiers in Immunology, 2022
Common human coronaviruses have been circulating undiagnosed worldwide. These common human coronaviruses share partial sequence homology with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); therefore, T cells specific to human coronaviruses
You-Seok Hyun   +11 more
doaj   +1 more source

Current research status of HLA in immune‐related diseases

open access: yesImmunity, Inflammation and Disease, 2021
Human leukocyte antigen (HLA), also known as human major histocompatibility complex (MHC), is encoded by the HLA gene complex, and is currently known to have the highest gene density and the most polymorphisms among human chromosomal areas.
Bingnan Liu, Yuanyuan Shao, Rong Fu
doaj   +1 more source

Comprehensive analysis of mycobacterium tuberculosis antigen-specific CD4+ T cell responses restricted by single HLA class II allotype in an individual

open access: yesFrontiers in Immunology, 2022
Mycobacterium tuberculosis infection is generally asymptomatic as latent tuberculosis, but it is still known as the world’s leading bacterial cause of death.
Yong-Hun Lee   +11 more
doaj   +1 more source

PECULIARITIES OF HLA-PHENOTYPES IN PATIENTS WITH PYELONEPHRITIS [PDF]

open access: yesAnnals of Mechnikov's Institute, 2016
Introduction. Of great interest are the studies on the role of human leucocyte antigens (HLA) in pathogenesis of a disease. The kidneys is vulnerable to injury in the context of inflammatory responses, with the potential involvement of a number of ...
Haiseniuk F, Driyanska V, Kruglikov V
doaj   +1 more source

Not All Antibodies Are Created Equal: Factors That Influence Antibody Mediated Rejection. [PDF]

open access: yes, 2017
Consistent with Dr. Paul Terasaki's "humoral theory of rejection" numerous studies have shown that HLA antibodies can cause acute and chronic antibody mediated rejection (AMR) and decreased graft survival. New evidence also supports a role for antibodies
Butler, Carrie L   +3 more
core   +7 more sources

Study of HLA-A and HLA-DR Polymorphism in Local Population, Pakistan

open access: yesTSF Journal of Biology, 2023
The compatibility of human leukocyte antigen (HLA) between donor and recipient is a major threat during kidney transplantation. HLA alleles are highly diverse among different individuals of the same population.
Khizra Aslam   +2 more
doaj   +1 more source

Characteristics of graft-infiltrating lymphocytes after human heart transplantation: HLA mismatches and the cellular immune response within the transplanted heart [PDF]

open access: yes, 1994
The influence of HLA mismatches between donor and recipient on the phenotypes, function, and specificity of T-lymphocyte cultures derived from endomyocardial biopsies was studied in 118 heart transplant recipients.
Baan, C.C. (Carla)   +7 more
core   +1 more source

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