Origin of lymph node-derived lymphocytes in human hepatic allografts [PDF]
Hepatic allograft-derived lymph nodes were examined in the post-transplant period on order to determine the origin of lymphocytes and structural elements of the lymph node.
Chen, K +7 more
core +1 more source
Unraveling the Role of Allo-Antibodies and Transplant Injury. [PDF]
Alloimmunity driving rejection in the context of solid organ transplantation can be grossly divided into mechanisms predominantly driven by either T cell-mediated rejection (TCMR) and antibody-mediated rejection (ABMR), though the co-existence of both ...
Matsuda, Yoshiko, Sarwal, Minnie M
core +5 more sources
Cancer vaccines: uses of HLA transgenic mice compared to genetically modified mice [PDF]
Many tumor antigens have been identified that can be targeted by the immune system. Animal models that have been genetically modified to express human HLA molecules instead of their own MHC antigens have shown to be valuable in the discovery of peptides ...
McArdle, SE
core
Polymorphism of the tumor necrosis factor beta gene in systemic lupus erythematosus [PDF]
We investigated the Nco I restriction fragment length polymorphism (RFLP) of the tumor necrosis factor beta (TNFB) gene in 173 patients with systemic lupus erythematosus (SLE), 192 unrelated healthy controls, and eleven panel families, all of German ...
Albert, E. D. +6 more
core +1 more source
Introduction: Genes encoding for human leukocyte antigens (HLA) are highly polymorphic and of great importance in organ transplantation procedures, as determining allelic frequencies in defined populations is taken into account among the scientific ...
Yazmin Rocío Arias +4 more
doaj +1 more source
Association of HLA-Class I antigens and haplotypes with relapse of pulmonary tuberculosis in patients treated with short course chemotherapy [PDF]
Whether or not there is an association between HLA antigen(s) and/or haplotypes aud relapse in patients successfully treated for pulmonary tuberculosis was examined.
Narayanan, P R +6 more
core
Screening of a HUVEC cDNA library with transplant-associated coronary artery disease sera identifies RPL7 as a candidate autoantigen associated with this disease. [PDF]
A HUVEC cDNA library was screened with sera from two patients who had developed transplant-associated coronary artery disease (TxCAD) following cardiac transplantation.
Linke, A.T. +5 more
core +4 more sources
Quantitative predictions of peptide binding to any HLA-DR molecule of known sequence: NetMHCIIpan.
CD4 positive T helper cells control many aspects of specific immunity. These cells are specific for peptides derived from protein antigens and presented by molecules of the extremely polymorphic major histocompatibility complex (MHC) class II system. The
Morten Nielsen +7 more
doaj +1 more source
Human germinal center B cells differ from naive and memory B cells by their aggregated MHC class II‐rich compartments lacking HLA‐DO [PDF]
To generate memory B cells bearing high‐affinity antibodies, naive B cells first encounter antigen in the T cell‐rich areas of secondary lymphoid organs.
Banchereau, Jacques +4 more
core
Behaviour of non-donor specific antibodies during rapid re-synthesis of donor specific HLA antibodies after antibody incompatible renal transplantation [PDF]
Background: HLA directed antibodies play an important role in acute and chronic allograft rejection. During viral infection of a patient with HLA antibodies, the HLA antibody levels may rise even though there is no new immunization with antigen ...
Briggs, David, Dr. +11 more
core +6 more sources

