Results 41 to 50 of about 58,639 (169)

Preservation of cytotoxic granule production in response to mycobacterial antigens by T-lymphocytes from vertically HIV-infected Brazilian youth on effective combined antiretroviral therapy

open access: yesBrazilian Journal of Infectious Diseases, 2019
Background: HIV infection harms adaptive cellular immunity mechanisms. Long-term virological control by combined antiretroviral therapy (cART) reduces the risk of mycobacterial infections.
Mauro Pedromonico Arrym   +8 more
doaj   +1 more source

HLA Class II Antigen Expression in Colorectal Carcinoma Tumors as a Favorable Prognostic Marker

open access: yesNeoplasia: An International Journal for Oncology Research, 2014
The goal of this study was to determine the frequency of HLA class II antigen expression in colorectal carcinoma (CRC) tumors, its association with the clinical course of the disease, and the underlying mechanism(s).
Giuseppe Sconocchia   +19 more
doaj   +1 more source

The human cytomegalovirus-encoded pUS28 antagonizes CD4+ T cell recognition by targeting CIITA

open access: yeseLife
Human cytomegalovirus (HCMV) is a relevant pathogen, especially for individuals with impaired immunity. Harnessing potent immune antagonists, HCMV circumvents sterile immunity. Given that HCMV prevents the upregulation of human leukocyte antigen (HLA)-DP
Fabienne Maassen   +14 more
doaj   +1 more source

HLA DR phenotypic frequencies and genetic risk of Type 1 diabetes in west region of Algeria, Tlemcen

open access: yesBMC Genetics, 2004
Background The main genomic region controlling the predisposition to type 1 diabetes is the Human Leukocyte Antigens (HLA) class II of the major histocompatibility complex. Association with different HLA types depends also on the studied populations.
Aribi Mourad   +3 more
doaj   +1 more source

Aspectos genéticos da esclerose múltipla: II. sistema HLA Genetic aspects in multiple sclerosis: HLA system

open access: yesArquivos de Neuro-Psiquiatria, 1996
Foi feita análise e revisão de estudos populacionais de associação entre antígenos HLA e a esclerose múltipla (EM). Há evidências de que os genes HLA, principalmente os de classe II, das sub-regiões DR e DQ possam estar envolvidos.
Patrícia Almeida de Rezende   +1 more
doaj   +1 more source

HLA-DR Antigen Expression in Primary Melanomas of the Skin

open access: yesJournal of Investigative Dermatology, 1984
Ninety-three primary malignant melanomas of the skin were typed immunohistologically for the expression of HLA-DR on tumor cells. HLA-DR-positive stroma cells were HLA-DR-negative or only locally positive in most cases. In 36 (39%) of the lesions more than 10% of the tumor cells were stained by two monoclonal antibodies against the nonpolymorphic ...
Bröcker, Eva-Bettina   +2 more
openaire   +2 more sources

Herpesviruses Placating the Unwilling Host: Manipulation of the MHC Class II Antigen Presentation Pathway

open access: yesViruses, 2012
Lifelong persistent infection by herpesviruses depends on the balance between host immune responses and viral immune evasion. CD4 T cells responding to antigens presented on major histocompatibility complex class II (MHC-II) molecules are known to play ...
Martin Rowe, Jianmin Zuo
doaj   +1 more source

CHANGES OF HLA-DR ANTIGEN EXPRESSION ON MONOCYTES IN CHILDREN AND THEIR CLINICAL SIGNIFICANCE IN SEPSIS

open access: yesМедицинская иммунология, 2014
. Temporary immunodeficiency is often associated with various pathological conditions, such as myocardial infarction, severe trauma, or major surgery. However, there are no clinical criterions indicative for presence or absence of such immune deficiency.
A. V. Zurochka   +6 more
doaj   +1 more source

Serum Soluble HLA-DR Antigens in Autoimmune Hepatitis

open access: yesAutoimmunity, 1999
To investigate the significance of HLA-class II, especially DR antigens, in autoimmune hepatitis (AIH), the serum concentrations of soluble HLA-DR antigen (sDR) were measured in 16 patients with AIH. The expression of HLA-DR antigens in the liver tissues of AIH patients was also studied by immunohistochemistry.
M, Hagihara   +8 more
openaire   +2 more sources

Association of HLA (Class I & II) and Susceptibility to Hydatid Cyst Disease

open access: yesمجلة كلية الطب, 2007
Background: Hydatid cyst disease is a parasitic zoonotic disease caused by genus Echinococcus. This disease believed to has genetic background in it's aetiopathogenesis course .
Ikbal Kh. Al-Joofy   +4 more
doaj  

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