Results 61 to 70 of about 108,857 (212)

Identification of antigens in BAL fluid in Sarcoidosis

Revista Portuguesa de Pneumologia, 2007
Activated T lymphocytes of the Th-1 type are typically accumulated in the lungs of patients with sarcoidosis, and there they may recognize specific sarcoidosis antigens, presented by antigen presenting cells such as dendritic cells and/or alveolar ...
Johan Grunewald
doaj   +1 more source

Targeting self- and foreign antigens to dendritic cells via DC-ASGPR generates IL-10-producing suppressive CD4+ T cells [PDF]

, 2012
Dendritic cells (DCs) can initiate and shape host immune responses toward either immunity or tolerance by their effects on antigen-specific CD4(+) T cells.
Akira, Anderson, Anna Karolina Palucka, Anne O’Garra, Anne-Laure Flamar, Awasthi, Bacchetta, Banchereau, Banchereau, Barrat, Baumgart, Bergman, Brown, Caparrós, Caux, Dapeng Li, Delneste, Dillon, Dorothée Duluc, Dudziak, Feng, Figdor, Gabrielle Romain, Gabrysová, Geijtenbeek, Geijtenbeek, Gerard Zurawski, Geurtsen, Gringhuis, Gringhuis, Groux, Häringer, Ito, Jacques Banchereau, Jankovic, Kaiser, Kappos, Klechevsky, LeibundGut-Landmann, Levings, Macián, Maldonado-López, Melissa Dullaers, Moore, Nathalie Bosquet, Ni, O’Garra, Pulendran, Reddy, Rissoan, Roger Le Grand, Rogers, Roncarolo, Sagoo, Saijo, Sandra Zurawski, SangKon Oh, Saraiva, Saraiva, Schreiber, Shortman, Smits, Soares, Steinman, Trinchieri, Valladeau, Xiao-Hua Li   +66 more
core   +2 more sources

Flow Cytometric Analysis of T, B, and NK Cells Antigens in Patients with Mycosis Fungoides

Journal of Immunology Research, 2015
We retrospectively analyzed the clinicopathological correlation and prognostic value of cell surface antigens expressed by peripheral blood mononuclear cells in patients with mycosis fungoides (MF). 121 consecutive MF patients were included in this study.
Serkan Yazıcı, Emel Bülbül Başkan, Ferah Budak, Barbaros Oral, Şaduman Balaban Adim, Zübeyde Ceylan Kalin, Güven Özkaya, Kenan Aydoğan, Hayriye Saricaoğlu, Şükran Tunali   +9 more
doaj   +1 more source

The relationship between human leukocyte antigens (HLA) and renal cell carcinoma

Biomolecules & Biomedicine, 2010
Etiologies of Renal Cell Carcinoma (RCC) are not clear despite of the fact that many risk factors have been suggested. Especially in high stages RCC can affect the immune system in various ways.
Erkan Yılmaz, Arman Çekmen, Emre Akkuş, Bülent Önal, Ali Uğur Özalp, Vural Solok, Ergun Erdoğan, Bülent Eren   +7 more
doaj   +1 more source

Challenges of monocyte HLA-DR targeted immunomodulation in sepsis—a prospective observational cohort study

Frontiers in Immunology
IntroductionReduced monocyte HLA-DR expression, a hallmark of immunosuppression in sepsis, is associated with infectious complications and mortality. Therapeutic strategies, including IFN-γ, have been used to restore monocyte HLA-DR and immune function ...
Timothy Arthur Chandos Snow, Antoine Villa, Antonio Cesar, Francis Ryckaert, Naveed Saleem, Deborah Smyth, Holly Pan, Julia Flint, David Brealey, David Brealey, Mervyn Singer, Derek W. Gilroy, Nishkantha Arulkumaran, the University College London Hospitals Critical Care Research Team   +13 more
doaj   +1 more source

The human leukocyte antigen system … simplified

Global Journal of Transfusion Medicine, 2017
Human leukocyte antigen (HLA) and transfusion medicine go hand in hand. Transfusion medicine experts are involved in transplants, particularly hematopoietic stem cell transplant.
Anand Deshpande
doaj   +1 more source

Preservation of cytotoxic granule production in response to mycobacterial antigens by T-lymphocytes from vertically HIV-infected Brazilian youth on effective combined antiretroviral therapy

Brazilian Journal of Infectious Diseases, 2019
Background: HIV infection harms adaptive cellular immunity mechanisms. Long-term virological control by combined antiretroviral therapy (cART) reduces the risk of mycobacterial infections.
Mauro Pedromonico Arrym, Paulo César Martins Alves, Mariana Virginello Castelhano, Taís Nitsch Mazzola, Renata Muller Banzato Pinto de Lemos, Tânia Regina Zaccariotto, Carlos Emilio Levy, Fernando Guimarães, Marcos Tadeu Nolasco da Silva   +8 more
doaj   +1 more source

Serum Soluble HLA-DR Antigens in Autoimmune Hepatitis

Autoimmunity, 1999
To investigate the significance of HLA-class II, especially DR antigens, in autoimmune hepatitis (AIH), the serum concentrations of soluble HLA-DR antigen (sDR) were measured in 16 patients with AIH. The expression of HLA-DR antigens in the liver tissues of AIH patients was also studied by immunohistochemistry.
M, Hagihara, K, Hosoi, T, Kagawa, B, Gansuvd, B, Munkhbat, T, Shimura, N, Watanabe, S, Matsuzaki, K, Tsuji   +8 more
openaire   +2 more sources

Determination of a predictive cleavage motif for eluted major histocompatibility complex class II ligands [PDF]

, 2018
CD4+ T cells have a major role in regulating immune responses. They are activated by recognition of peptides mostly generated from exogenous antigens through the major histocompatibility complex (MHC) class II pathway.
Dhanda, Sandeep Kumar, Edwards, Lindy, Jurtz, Vanessa, Karosiene, Edita, Nielsen, Morten, Paul, Sinu, Peters, Bjoern, Sette, Alessandro   +7 more
core   +6 more sources

HLA Class II Antigen Expression in Colorectal Carcinoma Tumors as a Favorable Prognostic Marker

Neoplasia: An International Journal for Oncology Research, 2014
The goal of this study was to determine the frequency of HLA class II antigen expression in colorectal carcinoma (CRC) tumors, its association with the clinical course of the disease, and the underlying mechanism(s).
Giuseppe Sconocchia, Serenella Eppenberger-Castori, Inti Zlobec, Eva Karamitopoulou, Roberto Arriga, Andrea Coppola, Sara Caratelli, Giulio Cesare Spagnoli, Davide Lauro, Alessandro Lugli, Junyi Han#, Giandomenica Iezzi, Cristina Ferrone, Amedeo Ferlosio, Luigi Tornillo, Raoul Droeser, Piero Rossi, Antonio Attanasio, Soldano Ferrone, Luigi Terracciano   +19 more
doaj   +1 more source