Results 21 to 30 of about 71,364 (318)

HLA‐DR antigens in gold‐induced neutropenia [PDF]

Arthritis & Rheumatism, 1986
We studied the clinical courses of 9 patients who developed acute gold-induced neutropenia with marrow aplasia. Eight of these carried HLA-DR4, compared with only 2 of 9 who had mild, chronic, isolated neutropenia (P less than 0.05). Only 1 of 9 patients with myelotoxicity carried HLA-DR3.
S, Aaron, P, Davis, J, Bertouch
openaire   +2 more sources

Impaired Intracellular Transport and Cell Surface Expression of Nonpolymorphic HLA-E [PDF]

, 1992
The assembly of the classical, polymorphic major histocompatibility complex class I molecules in the endoplasmic reticulum requires the presence of peptide ligands and ~2-microglobulin (~2m). Formation of this trimolecular complex is a prerequisite for e~
Kellermann, Josef, Johnson, Judith P., Matthias Ulbrecht, Ulbrecht, Matthias, Josef Kellermann, Judith P. Johnson, Weiss, Elisabeth H., Elisabeth H. Weiss   +7 more
core   +1 more source

Emergence of highly profibrotic and proinflammatory Lrat+Fbln2+ HSC subpopulation in alcoholic hepatitis

Hepatology, EarlyView., 2022
Lrat+ quiescent hepatic stellate cells (qHSC) give rise to Lrat+Fbln2+ activated HSC (aHSC) in alcohol‐associated hepatitis and this subpopulation is highly profibrotic, inflammatory, and immunoregulatory based on their single cell transcriptomic profile. Abstract Background and Aims Relative roles of HSCs and portal fibroblasts in alcoholic hepatitis (
Steven Balog, Reika Fujiwara, Stephanie Q. Pan, Khairat B. El‐Baradie, Hye Yeon Choi, Sonal Sinha, Qihong Yang, Kinji Asahina, Yibu Chen, Meng Li, Matthew Salomon, Stanley W.‐K. Ng, Hidekazu Tsukamoto   +12 more
wiley   +1 more source

Human Leukocyte Antigen (HLA) Frequencies and 4-loci HLA Haplotype Frequencies in Southern Thailand

Journal of Health Science and Medical Research (JHSMR)
Objective: To determine the antigen and haplotype frequencies of human leukocyte antigen-A (HLA-A), -B, -DRB1, and -DQB1 in southern Thailand. Material and Methods: We retrospectively analyzed HLA typing data from patients treated at Songklanagarind ...
Kantarat Kusolthammarat, Wanwimon Yindee, Jarin Buakaew, Rassamee Chotipanvithayakul, Kanoot Jaruthamsophon   +4 more
doaj   +1 more source

Evaluation of 28 Human Embryonic Stem Cell Lines for Use as Unrelated Donors in Stem Cell Therapy: Implications of HLA and ABO Genotypes

Cell Transplantation, 2010
For human embryonic stem cells (hESCs) to be used clinically, it is imperative that immune responses evoked by hESCs and their derivates after transplantation should be prevented.
Jeoung Eun Lee, Myung Seo Kang, Myoung Hee Park, Sung Han Shim, Tae Ki Yoon, Hyung Min Chung, Dong Ryul Lee Ph.D.   +6 more
doaj   +1 more source

EVALUATION OF HUMAN LEUKOCYTE ANTIGEN CLASS I AND II ANTIGENS IN HELICOBACTER PYLORI-POSITIVE PEDIATRIC PATIENTS WITH ACTIVE GASTRITIS AND DUODENAL ULCER

Arquivos de Gastroenterologia, 2017
BACKGROUND: As being the first bacteria determined to be carcinogenic, Helicobacter pylori (H. pylori) is a pathogen localized in the stomach in more than half of the world population.
Sevim GÖNEN, Sinan SARI, Yaşar KANDUR, Buket DALGIÇ, Oğuz SÖYLEMEZOĞLU   +4 more
doaj   +1 more source

Autoimmune and non-autoimmune thyroid diseases have different patterns of cellular HLA class II expression

São Paulo Medical Journal
CONTEXT: Surface HLA-DR antigen is usually only expressed by antigen-presenting cells (APC). In autoimmune thyroid disease, follicle cells function as APC, thus expressing HLA-DR. However, non-autoimmune thyroid diseases may also express surface class II
Denise Engelbrecht Zantut-Wittmann, Luís Henrique Barbosa Boechat, Glauce Aparecida Pinto, Miriam Aparecida da Silva Trevisan, José Vassallo   +4 more
doaj   +1 more source

A distinct subset of human NK cells expressing HLA-DR expand in response to IL-2 and can aid immune responses to BCG. [PDF]

, 2011
Subsets of NK cells can have distinct functions. Here, we report that >25% of human peripheral blood NK cells express HLA-DR after culture with IL-2.
Emma L. Wise, Riley, Eleanor M, Pease, James E, Horowitz, Amir, Evans, J Henry, Eleanor M. Riley, Riley, Eleanor M., James E. Pease, Wise, Emma L., Pease, James E., Davis, Daniel M., Wise, Emma L, Davis, Daniel M, J. Henry Evans, Mehrabi, Maryam, Maryam Mehrabi, Daniel M. Davis, Amir Horowitz, Evans, J. Henry   +18 more
core   +1 more source

Idiopathic focal segmental glomerulosclerosis and HLA antigens

Brazilian Journal of Medical and Biological Research, 1998
The objective of the present study was to investigate a possible association between HLA class II antigens and idiopathic focal segmental glomerulosclerosis (FSGS).
M. Gerbase-DeLima, A. Pereira-Santos, R. Sesso, J. Temin, E.S. Aragão, H. Ajzen   +5 more
doaj   +1 more source

Association of Alport's syndrome with HLA-DR2 antigen in a group of unrelated patients

Brazilian Journal of Medical and Biological Research, 1998
A few family studies have evaluated HLA antigens in Alport's syndrome; however, there are no large population studies. In the present report, we studied 40 unrelated white patients with Alport's syndrome seen at the Unit of Renal Transplantation, Faculty
E.A. Donadi, J.C. Voltarelli, C.M. Paula-Santos, T. Kimachi, A.S. Ferraz   +4 more
doaj   +1 more source