Three HLA-D region antigens defined by primed LD typing. [PDF]
We have recently described a new method, primed LD typing or PLT, for specific identification of HLA-D antigens. Highly discriminatory PLT cells have been developed which clearly differentiate between cells of individuals that restimulate strongly and those that restimulate weakly.
Paul M Sondel, Marilyn L Bach, Bach F H
exaly +3 more sources
HLA–D region antigens in patients with rheumatoid arthritis [PDF]
AbstractWe studied the distribution of HLA–D region antigens in 2 groups of rheumatoid arthritis (RA) patients: those with mild, nonprogressive disease, and those with severe disease. The results demonstrate that DR4 was significantly increased in both RA patient populations.
C T, McCusker +5 more
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A novel HLA-D/DR-like antigen specific for human B lymphoid cells. Biochemical evidence for similarity to but nonidentity with known HLA-D/DR antigens. [PDF]
The polymorphic human B cell-specific antigen, 33.1, detected by a murine monoclonal antibody, was compared by genetics and structural analysis with known human Ia antigens from a panel of DR homozygous Epstein-Barr virus-transformed B lymphoblastoid cell lines. Cells homozygous for DR 1, 2, 4, 5, and w6 were positive, while cells that are DR3,3 or DR7,
G E, Marti +7 more
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HLA-D Region Antigen Expression by Human Epidermal Langerhans Cells
We have systematically examined HLA-D region antigen expression by normal human epidermal Langerhans cells with an improved double label indirect immunofluorescence technique in order to better understand the immunologic potential of this human interstitial dendritic cell type.
Sontheimer, Richard D +2 more
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HLA-D and -DR antigens in genetic analysis of insulin dependent diabetes mellitus [PDF]
Three groups of patients with insulin-dependent diabetes mellitus, ascertained by different procedures, were investigated for HLA-A, B, C and D antigens (n = 164), and a subset (n = 93) for HLA-DR. Both HLA-D/DR3 and D/DR4 were strongly positively associated and D/DR2 was negatively associated with insulin-dependent diabetes.
P, Platz +11 more
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HLA-D and IA antigens in rheumatoid arthritis and systemic lupus erythematosus [PDF]
The HLA-D region in the HLA chromosomal complex is concerned with cellular interactions and regulation of the immune response. Rheumatoid arthritis (RA) has been found to be associated with one of the HLA-D antigens. In two separate studies from this laboratory it was found that HLA-Dw4 was more frequent in RA patients than in normal controls.
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HLA-D associated alloantisera react with molecules similar to Ia antigens. [PDF]
Two human alloantisera specific to bone marrow-derived lymphocytes (B cells) were shown to precipitate polypeptide chains of 29,000 and 34,000 daltons from human lymphoblastoid B cell lines. These molecules are similar to murine Ia antigens and are also precipitated by a rabbit B-cell specific heteroantiserum.
M J, Giphart +6 more
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HLA-D antigens in a Czech population and their association with HLA-DR antigens.
HLA-D specificities Dwl through 11 and HLA-DR antigens DRwl through WIA8 were studied on a panel of 101 unrelated individuals of the Prague HLA panel. THe HLA-D specificities were defined by means of the HLA-D homozygous typing cells in MLC test, the HLA-DR specificities were tested on B cells using VIIth Histocompatibility Workshop antisera.
E, Hinzová +3 more
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HLA‐D Antigens in the Japanese Population
Tissue Antigens, 1977A Japanese population was typed for HLA‐D antigens for the first time using HLA‐D homozygous typing cells Dw1 through Dw4 and the homozygous cells LD HO and LD AH, newly found in the Japanese population. Dw3 was absent from the Japanese population which also lacks B8.
T, Sasazuki +3 more
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HLA-D Antigens and Paget's Disease of Bone
Clinical Orthopaedics and Related Research, 1991HLA-A, -B, -C, -DR, and -DQ antigens were determined in 25 Ashkenazi Jews with Paget's disease of bone. HLA-DR2 was more frequent in the Pagetic patients compared with 57 healthy controls of the same ethnic origin. This finding concurs with a previous report and raises the possibility that HLA-DR2 may be associated with Paget's disease of bone ...
J, Foldes +4 more
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