Results 1 to 10 of about 375,043 (313)

Three HLA-D region antigens defined by primed LD typing. [PDF]

open access: yesThe Journal of experimental medicine, 1976
We have recently described a new method, primed LD typing or PLT, for specific identification of HLA-D antigens. Highly discriminatory PLT cells have been developed which clearly differentiate between cells of individuals that restimulate strongly and those that restimulate weakly.
F H, Bach   +5 more
openaire   +3 more sources

HLA-D and IA antigens in rheumatoid arthritis and systemic lupus erythematosus [PDF]

open access: yesArthritis & Rheumatism, 1978
The HLA-D region in the HLA chromosomal complex is concerned with cellular interactions and regulation of the immune response. Rheumatoid arthritis (RA) has been found to be associated with one of the HLA-D antigens. In two separate studies from this laboratory it was found that HLA-Dw4 was more frequent in RA patients than in normal controls.
P. Stastny
openaire   +3 more sources

HLA–D region antigens in patients with rheumatoid arthritis [PDF]

open access: yesArthritis & Rheumatism, 1991
AbstractWe studied the distribution of HLA–D region antigens in 2 groups of rheumatoid arthritis (RA) patients: those with mild, nonprogressive disease, and those with severe disease. The results demonstrate that DR4 was significantly increased in both RA patient populations.
C T, McCusker   +5 more
openaire   +3 more sources

HLA-D and -DR antigens in genetic analysis of insulin dependent diabetes mellitus [PDF]

open access: yesDiabetologia, 1981
Three groups of patients with insulin-dependent diabetes mellitus, ascertained by different procedures, were investigated for HLA-A, B, C and D antigens (n = 164), and a subset (n = 93) for HLA-DR. Both HLA-D/DR3 and D/DR4 were strongly positively associated and D/DR2 was negatively associated with insulin-dependent diabetes.
P, Platz   +11 more
openaire   +3 more sources

HLA-D associated alloantisera react with molecules similar to Ia antigens. [PDF]

open access: yesProceedings of the National Academy of Sciences, 1977
Two human alloantisera specific to bone marrow-derived lymphocytes (B cells) were shown to precipitate polypeptide chains of 29,000 and 34,000 daltons from human lymphoblastoid B cell lines. These molecules are similar to murine Ia antigens and are also precipitated by a rabbit B-cell specific heteroantiserum.
M J, Giphart   +6 more
openaire   +3 more sources

A novel HLA-D/DR-like antigen specific for human B lymphoid cells. Biochemical evidence for similarity to but nonidentity with known HLA-D/DR antigens. [PDF]

open access: yesThe Journal of experimental medicine, 1983
The polymorphic human B cell-specific antigen, 33.1, detected by a murine monoclonal antibody, was compared by genetics and structural analysis with known human Ia antigens from a panel of DR homozygous Epstein-Barr virus-transformed B lymphoblastoid cell lines. Cells homozygous for DR 1, 2, 4, 5, and w6 were positive, while cells that are DR3,3 or DR7,
G E, Marti   +7 more
openaire   +3 more sources

Matching strategy for patients with platelet transfusion refractoriness caused by compound antibodies against HLA and CD36

open access: yesZhongguo shuxue zazhi, 2023
Objective To search compatible and suitable platelets for platelet transfusion refractoriness (PTR) patient caused by compound antibodies against HLA and CD36.
Jing DENG   +10 more
doaj   +1 more source

HLA as risk and protection antigens against urinary tract diseases

open access: yesУкраїнський Журнал Нефрології та Діалізу, 2022
. Currently, there is no doubt about the feasibility of determining the frequency of HLA and analysis of genetic associations, including those that determine the state of immunity, in patients with the genitourinary disease.
M. Kolesnyk   +11 more
doaj   +1 more source

Chimerism Revisited: Perspective of an Immunopathologist [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2023
Introduction: Chimerism analysis is an important diagnostic tool not only for assessing the risk of relapse after allo-Haematopoietic Stem Cell Transplant (HSCT) in patients with malignant diseases, it is also the predominant method for monitoring post ...
Devika Gupta   +3 more
doaj   +1 more source

Allo-Specific Humoral Responses: New Methods for Screening Donor-Specific Antibody and Characterization of HLA-Specific Memory B Cells

open access: yesFrontiers in Immunology, 2021
Antibody-mediated allograft rejection (AMR) causes more kidney transplant failure than any other single cause. AMR is mediated by antibodies recognizing antigens expressed by the graft, and antibodies generated against major histocompatibility complex ...
Shengli Song   +7 more
doaj   +1 more source

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