Results 31 to 40 of about 375,043 (313)

Discovery and Differential Processing of HLA Class II-Restricted Minor Histocompatibility Antigen LB-PIP4K2A-1S and Its Allelic Variant by Asparagine Endopeptidase [PDF]

, 2020
Minor histocompatibility antigens are the main targets of donor-derived T-cells after allogeneic stem cell transplantation. Identification of these antigens and understanding their biology are a key requisite for more insight into how graft vs.
Bausenwein, Judith, Falkenburg, J. H. Frederik, Griffioen, Marieke, Honders, Maria W., Kremer, Andreas E., Kremer, Anita N., Kretschmann, Sascha, Lurvink, Ellie, Mackensen, Andreas, Mazzeo, Daniela, Rutten, Caroline E., van Bergen, Cornelis A. M., van der Meijden, Edith, Watts, Colin   +13 more
core   +2 more sources

Disease recurrence and rejection following liver transplantation for autoimmune chronic active liver disease [PDF]

, 1992
Autoimmune chronic active liver disease (ACALD), a major indication for liver transplantation, is associated strongly with antigenic determinants HLA-B8 and DR3.
Block, GD, Bou-Abboud, CF, Demetris, AJ, Hassanein, T, Starzl, TE, Van Thiel, DH, Wright, HL   +6 more
core   +1 more source

Multiscale genetic architecture of donor-recipient differences reveals intronic LIMS1 mismatches associated with kidney transplant survival

The Journal of Clinical Investigation, 2023
Donor-recipient (D-R) mismatches outside of human leukocyte antigens (HLAs) contribute to kidney allograft loss, but the mechanisms remain unclear, specifically for intronic mismatches. We quantified non-HLA mismatches at variant-, gene-, and genome-wide
Zeguo Sun, Zhongyang Zhang, Khadija Banu, Ian W. Gibson, Robert B. Colvin, Zhengzi Yi, Weijia Zhang, Bony De Kumar, Anand Reghuvaran, John Pell, Thomas D. Manes, Arjang Djamali, Lorenzo Gallon, Philip J. O’Connell, John Cijiang He, Jordan S. Pober, Peter S. Heeger, Madhav C. Menon   +17 more
doaj   +1 more source

HLA-D Region Antigen Expression by Human Epidermal Langerhans Cells

Journal of Investigative Dermatology, 1986
We have systematically examined HLA-D region antigen expression by normal human epidermal Langerhans cells with an improved double label indirect immunofluorescence technique in order to better understand the immunologic potential of this human interstitial dendritic cell type.
Sontheimer, Richard D, Stastny, Peter, Nunez, Gabriel   +2 more
openaire   +2 more sources

Risk of Transfusion Complication: A Systematic Review of Iranian Literature [PDF]

Journal of Shahrekord University of Medical Sciences
Background and aims: Injecting healthy blood on time can save patients’ lives; on the other hand, delaying the start of transfusion or injecting unhealthy and wrong blood can cause fatal risks.
Hamidreza Azizi Farsani, Noormohammad Arefian, Faranak Behnaz, Arash Tafrishinejad, Padideh Ansar, Zahra Azizi Farsani, Abolfazl Azizi Farsani   +6 more
doaj   +1 more source

Allelic variation in HLA-B and HLA-C sequences and the evolution of the HLA-B alleles [PDF]

, 1989
Several new HLA-B (B8, B51, Bw62)- and HLA-C (Cw6, Cw7)-specific genes were isolated either as genomic cosmid or cDNA clones to study the diversity of HLA antigens.
Doerner, C., Kuon, W., Pohla, Heike, Tabaczewski, P., Weiss, Elisabeth H.   +4 more
core   +1 more source

New insights into the genetic diversity, phylogeny, and immunogenic potential of the wsp gene in Wolbachia endosymbionts in Brugia malayi and Brugia pahangi

Current Research in Parasitology and Vector-Borne Diseases
Wolbachia spp. are intracellular, maternally inherited bacteria that infect a wide range of arthropods. These bacteria influence reproductive traits in their hosts and are used in mosquito-borne virus control programmes.
Witchuta Junsiri, Piyanan Taweethavonsawat   +1 more
doaj   +1 more source

Cancer vaccines: uses of HLA transgenic mice compared to genetically modified mice [PDF]

, 2008
Many tumor antigens have been identified that can be targeted by the immune system. Animal models that have been genetically modified to express human HLA molecules instead of their own MHC antigens have shown to be valuable in the discovery of peptides ...
McArdle, SE
core  

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

The Humoral Theory of Transplantation: Epitope Analysis and the Pathogenicity of HLA Antibodies. [PDF]

, 2016
Central to the humoral theory of transplantation is production of antibodies by the recipient against mismatched HLA antigens in the donor organ. Not all mismatches result in antibody production, however, and not all antibodies are pathogenic.
Farber, John, Filippone, Edward J
core   +4 more sources