Results 1 to 10 of about 64,657 (130)

Response of HL-A Identical Unrelated Individuals in the Mixed Lymphocyte Culture Test [PDF]

open access: yesBMJ, 1971
The immunological responsiveness as measured in the mixed lymphocyte culture test has been studied in 13 pairs of HL-A identical unrelated individuals. In all combinations stimulation occurred and it was frequently of a similar magnitude to that observed against non-HL-A identical subjects.It is postulated that another locus, adjacent to the HL-A locus,
J M, Johnston, H V, Bashir
openaire   +2 more sources

The predictive value of stimulation index calculated by modified mixed lymphocyte culture in the detection of GVHD following hematopoietic stem cell transplantation

open access: yesTurkish Journal of Hematology, 2010
OBJECTIVE: Mixed lymphocyte culture (MLC) is one of the routine tests performed prior to hematopoietic stem cell transplantation (HSCT) as a predictive assay for assessing the quality of donor matching and graft-versus-host disease (GVHD).
Hülya Sayılan Şen   +9 more
doaj   +3 more sources

Preparation of trivalent vaccine against lumpy skin disease using different capripox viral strain [PDF]

open access: yesVeterinary Medical Journal - Giza, 2018
Vaccination is considered the most effective measure to control lumpy skin disease, Various types of Capripoxvirus vaccine strains are used in vaccination programs. In Egypt, since the appearance of LSD in 1988, various live attenuated sheep pox vaccines
S El Soally   +4 more
doaj   +1 more source

In vitro testing of immunosupressive effects of mesenchymal stromal cells on lymphocytes stimulated with alloantigens

open access: yesBiomedical Papers, 2015
Aims: Mesenchymal stromal cells (MSC) derived from adult bone marrow or adipose tissue offer the potential to open a new frontier in medicine. MSC are involved in modulating immune response and tissue repair in vitro and in vivo.
Daniel Lysak   +4 more
doaj   +1 more source

The Therapeutic Effect of ICAM-1-Overexpressing Mesenchymal Stem Cells on Acute Graft-Versus-Host Disease

open access: yesCellular Physiology and Biochemistry, 2018
Background/Aims: Mesenchymal stem cells (MSCs) do not readily migrate to appropriate sites, and this creates a major obstacle for their use in the treatment of graft-versus-host disease (GVHD).
Bo Tang   +10 more
doaj   +1 more source

Microbial antigens-loaded myeloma cells enhance Th2 cell proliferation and myeloma clonogenicity via Th2–myeloma cell interaction

open access: yesBMC Cancer, 2019
Background Myeloma cells retain B cell functions, considered to be potential antigen presenting cells, yet there is little information regarding promoting Th2 cell proliferation or the direct effects to myeloma on the Th2 cells stimulated by microbial ...
Faqing Tian   +8 more
doaj   +1 more source

Comparative Phenotype and Immunogenicity of Freshly Isolated and Immortalized Rat Hepatocytes

open access: yesCell Transplantation, 2001
Immortalized hepatocytes are an attractive cell source for hepatocyte transplantation and gene transfer. We compared the phenotype and immunogenicity of freshly isolated (FIH) and immortalized (IMH) rat hepatocytes.
Vincent Kaulek   +8 more
doaj   +1 more source

Positive Mixed Lymphocyte Culture Test Result Due To Hla –dp Mismatch

open access: yesMedical Journal of Trakya University, 2009
Graft Versus Host Disease (GVHD) remains a major cause of morbidity and mortality in allogeneic stem cell transplantation (SCT). The MLC assay has been generally accepted as a standard test for determining HLA-D region compatibility. In this study, the MLC test has been carried out on the related recipient-donor couple who were prepared for allogeneic ...
AYNA, Tülay Kılıçaslan   +7 more
openaire   +4 more sources

Inhibitory serum factor of lymphoproliferative response to allogeneic cells in pregnancy

open access: yesSão Paulo Medical Journal
INTRODUCTION: An inhibitory serum factor of mixed lymphocyte culture (MLC) has been associated with successful pregnancy after lymphocyte transfusion in women with unexplained recurrent spontaneous abortions (RSA).
Silvia Daher   +4 more
doaj   +1 more source

Rapid mixed lymphocyte culture testing by analysis of the insulin receptor on alloactivated T lymphocytes: implications for human tissue typing. [PDF]

open access: yesJournal of Clinical Investigation, 1981
Responses in the mixed lymphocyte culture (MLC) are traditionally evaluated by measurement of DNA synthesis or blast transformation. However, these events occur too late in the MLC to permit prospective matching for cadaveric renal transplantation.
J H, Helderman, T B, Strom, M R, Garovoy
openaire   +2 more sources

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