Co-delivery of human cancer-testis antigens with adjuvant in protein nanoparticles induces higher cell-mediated immune responses. [PDF]
, 2018 Nanoparticles have attracted considerable interest as cancer vaccine delivery vehicles for inducing sufficient CD8+ T cell-mediated immune responses to overcome the low immunogenicity of the tumor microenvironment.
Kim, Tae Il +5 more
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Association of Alport's syndrome with HLA-DR2 antigen in a group of unrelated patients
Brazilian Journal of Medical and Biological Research, 1998 A few family studies have evaluated HLA antigens in Alport's syndrome; however, there are no large population studies. In the present report, we studied 40 unrelated white patients with Alport's syndrome seen at the Unit of Renal Transplantation, Faculty
E.A. Donadi +4 more
doaj +1 more source
Distinct Intracellular Compartments Involved in Invariant Chain Degradation and Antigenic Peptide Loading of Major Histocompatibility Complex (MHC) Class II Molecules [PDF]
, 1997 Major histocompatibility complex (MHC) class II molecules are transported to intracellular MHC class II compartments via a transient association with the invariant chain (Ii).
Ferrari, G. +3 more
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HLA-DR antigen-positive acute promyelocytic leukemia
Experimental and Molecular Pathology, 2016 Acute promyelocytic leukemia (APL) with t(15;17)(q22;q21)/PML-RARα is a subtype of acute myeloid leukemia (AML) with distinct morphologic and immunophenotypic characteristics. It is a highly aggressive disease that requires rapid diagnosis and early intervention.
Alejandro S. Mendoza +5 more
openaire +2 more sources
Immunological Compatibility Status of Placenta-Derived Stem Cells is Mediated by Scaffold 3D Structure [PDF]
, 2018 Placenta-derived amniotic epithelial cells (AECs), a great cell source for tissue engineering and stem cell therapy, are immunologically inert in their native state; however, immunological changes in these cells after culture and differentiation have ...
Azizian, Sara +8 more
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Memorias do Instituto Oswaldo Cruz, 1990 Epidermal changes from 32 cutaneous and 3 mucosal American leishmaniasis (ACL) active lesions were studied for HLA-DR, -DP expression, Lanerhans cells and lymphocyte infiltration.
Claude Pirmez +3 more
doaj +1 more source
HLA-DR phenotypes and lymphocyte response to M. tuberculosis antigens and in cured spinal tuberculosis patients and their contacts [PDF]
, 2004 Background: Our earlier studies on Human Leucocyte Antigens (HLA) in pulmonary tuberculosis patients revealed the association of HLA-DR2 antigen with susceptibility to pulmonary TB and DR2 antigen has been shown to influence the immunity to ...
Charles, N +4 more
core
DY determinants, possibly associated with novel class II molecules, stimulate autoreactive CD4+ T cells with suppressive activity [PDF]
, 1988 A set of T cell clones (TCC) isolated from HLA-DR-, Dw-, DQ-matched allogeneic MLCs was found to proliferate autonomously when stimulated with cells carrying a wide range of class I or II specificities.
Brocker, Thomas +5 more
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HLA DR antigens and gold toxicity. [PDF]
Annals of the Rheumatic Diseases, 1983 One hundred and thirty-two patients with rheumatoid arthritis treated with gold have been studied for possible associations between HLA DR antigens and different adverse reactions occurring during such therapy. Patients possessing HLA DR3 had a significantly greater frequency of side effects than patients lacking this antigen.
J T, Gran, G, Husby, E, Thorsby
openaire +2 more sources
Human leukocyte antigens and genetic susceptibility to lymphoma [PDF]
, 2015 Familial aggregation, coupled with ethnic variation in incidence, suggests that inherited susceptibility plays a role in the development of lymphoma, and the search for genetic risk factors has highlighted the contribution of the human leukocyte antigen (
Jarrett, R.F., McAulay, K.A.
core +1 more source